Rogelio Rodríguez-Talavera
National Autonomous University of Mexico
ProdrugSelf-healing hydrogelsSurface modificationPlasma polymerizationSubstrate (chemistry)BiophysicsElectrospinningDegradation (geology)CopolymerFourier transform infrared spectroscopyMonomerChemistryPolymer chemistryMaterials scienceIn vitroGraftingIsoniazidBiocompatibilityEthylene glycolMycobacterium tuberculosisBiomaterialBiopolymerAcrylamidePolyurethaneDrugFibroblastPolyhydroxybutyrateDifferential scanning calorimetryMembraneChemical engineeringPolymerizationCrystallinityTissue engineeringConnective tissuePolymerViability assayPEG ratioPotencySurface finishPharmacology
5Publications
2H-index
17Citations
Publications 5
Newest
Polyhydroxybutyrate (PHB) scaffolds, produced by electrospinning and coated by plasma polymerization of pyrrole, were used as cell culture substrate for beta cells. PHB is a natural polymer that is biocompatible and bioresorbable. The electrospinning conditions used, produced scaffolds with large surface area and high porosity. The scaffold surface was modified by plasma polymerization of pyrrole doped with iodine (PPyI). The morphology of the scaffolds was characterized by scanning electron mic...
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#1Eric Ivan Ochoa-Segundo (UNAM: National Autonomous University of Mexico)H-Index: 1
Last. Rogelio Rodríguez-Talavera (UNAM: National Autonomous University of Mexico)H-Index: 2
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Abstract This study aimed at investigating the synthesis, characterization, and search for a biotechnological application proposal for poly [(R)-3-hydroxybutyric acid] (PHB) grafted with the n-hydroxyethyl acrylamide (HEAA) monomer. The novel copolymer was prepared by 60Co gamma radiation-induced-graft polymerization. The effect of different solvents in the graft polymerization; the degree of grafting, crystallinity, and hydrophilicity; the morphology and the thermal properties were evaluated. T...
2 CitationsSource
#1Maykel González Torres (Tec: Monterrey Institute of Technology and Higher Education)H-Index: 2
#1Maykel González-Torres (Tec: Monterrey Institute of Technology and Higher Education)H-Index: 6
Last. Rogelio Rodríguez-Talavera (UNAM: National Autonomous University of Mexico)H-Index: 2
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Background: The search for innovative anti-tubercular agents has received increasing attention in tuberculosis chemotherapy because Mycobacterium tuberculosis infection has steadily increased over the years. This underlines the necessity for new methods of preparation for polymer-drug adducts to treat this important infectious disease. The use of poly(ethylene glycol)(PEG) is an alternative producing anti-tubercular derivatives. However, it is not yet known whether PEGylated isonicotinylhydrazid...
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#1Maykel González-Torres (UNAM: National Autonomous University of Mexico)H-Index: 6
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Abstract The synthesis of novel degradable hydrogels, with designable structures and good biocompatibility, produces attractive materials for use in connective tissue regeneration applications. However, the way in which human fibroblast cells respond to terpolymer hydrogels such as collagen–polyvinylpyrrolidone–polyethylene glycol (C–PVP–PEG) remains largely unknown. The aim of this study was to synthesize a gamma-radiation-induced C–PVP–PEG hydrogel and to evaluate its structure, morphology and...
11 CitationsSource
#1Maykel González-Torres (UNAM: National Autonomous University of Mexico)H-Index: 6
#2Susana Vargas-Muñoz (UNAM: National Autonomous University of Mexico)H-Index: 1
Last. Rogelio Rodríguez-Talavera (UNAM: National Autonomous University of Mexico)H-Index: 2
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Abstract A new type of cell-carrier-scaffold based on the surface modification of poly(3-hydroxybutyrate- co -3-hydroxyvalerate) by direct plasma-radiation-induced graft polymerization of N-hydroxyethyl-acrylamide was prepared. Parameters such as the membrane position for plasma treatment, delivering power and exposure time were varied. The yields over the film surfaces, chemical changes, morphology and roughness were surveyed. The results indicate that the tailoring is more favorable at 10 W fo...
6 CitationsSource