John Sousa
University of Florida
EpidemiologyPsychiatryOligonucleotideObstetricsCross-sectional studyGene expressionMolecular biologyHealth carePediatricsEmergency medicineCohort studySystemic administrationSerotoninAbdominal wall defectHypothermiaGastroschisisWaiverRaphe nucleiGirlGestational ageRiboprobeDiseaseQuality of life (healthcare)OmphaloceleSerotonin syndromeHypertrophic cardiomyopathyStimulantMDMAPPIBNeonatal ICUsPeptidylprolyl isomeraseIntensive careCardiovascular healthHospital outcomesHospital treatmentPatient dataLevel iiPoor qualityRetrospective reviewNeonatal abstinenceHousekeeping geneSerotonergicIncidence (epidemiology)MicrodialysisNeonatology5-HT receptorMedical emergencyMedicineCohortIn situ hybridizationBiologyPharmacology
8Publications
3H-index
325Citations
Publications 8
Newest
#1John Sousa (UF: University of Florida)H-Index: 3
#2Russell B. Hawkins (UF: University of Florida)H-Index: 11
Last. Saleem Islam (UF: University of Florida)H-Index: 32
view all 8 authors...
Abstract null null Introduction null Enterobius vermicularis is known to be associated with appendicitis, however a causal relationship between Enterobius and appendicitis has not been established. The aim of this study was to explore the relationship between appendiceal Enterobius and histologic appendicitis. null null null Methods null A retrospective review was performed of all pediatric appendectomies between 1997 and 2019. Patients with diagnosed with Enterobius were included for analysis. ...
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#1Reese H. ClarkH-Index: 75
#2John Sousa (UF: University of Florida)H-Index: 3
Last. Veeral N. Tolia (Baylor University Medical Center)H-Index: 10
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Abstract Background/Purpose Gastroschisis incidence increased 300% in the United States from 1998 to 2013. We sought to assess trends in gastroschisis prevalence in the United States from 1997 to 2018 from a large NICU dataset. Methods We performed a retrospective review of all infants in the Pediatrix Clinical Data Warehouse from 1997 to 2018. Prevalence was calculated as number of infants with gastroschisis (among all NICU admissions) divided by the total number of NICU infants. Trends were an...
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#1Emily Senderey (FAU: Florida Atlantic University)H-Index: 1
#2John Sousa (UF: University of Florida)H-Index: 3
Last. Mark Stavitsky (UF: University of Florida)H-Index: 1
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A 10-year-old girl with attention-deficit hyperactivity disorder (ADHD) is diagnosed with hypertrophic cardiomyopathy. The stimulant medications used to control her ADHD pose possibly fatal risks to her cardiovascular health, so stimulant medication is stopped. Due to very poor quality of life off of medication, alternative therapies are used without improvement. The patient’s caretakers decide that the benefits of stimulant medication outweigh the risks to the patient. The healthcare team clear...
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#1Richard M. Allman (FIU: Florida International University)H-Index: 66
#2John Sousa (FAU: Florida Atlantic University)H-Index: 3
Last. Reese H. ClarkH-Index: 75
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The purpose of this study is to evaluate recent trends in prevalence of gastroschisis among infants admitted for neonatal intensive care in the United States. Retrospective review of a de-identified patient data. The current study extends our observations through the end of 2007 to 2015. During the study period (1 January 1997 to 12 December 2015), there were 1 158 755 total discharges; 6023 (5.2/1000) had gastroschisis and 1885 (1.6/1000) had an omphalocele. Between 1997 and 2008, the reported ...
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#1Ibrahim M. Shokry (Ross University School of Veterinary Medicine)H-Index: 3
#2John J. Callanan (Ross University School of Veterinary Medicine)H-Index: 6
Last. Rui Tao (FAU: Florida Atlantic University)H-Index: 3
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In spite of the fact that systemic administration of MDMA elicits serotonin syndrome, direct intracranial administration fails to reproduce the effect. To reconcile these findings, it has been suggested that the cause of serotonin syndrome is attributed mainly to MDMA hepatic metabolites, and less likely to MDMA itself. Recently, however, this explanation has been challenged, and alternative hypotheses need to be explored. Here, we tested the hypothesis that serotonin syndrome is the result of e...
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#1Veeral N. ToliaH-Index: 10
#2Stephen W. PatrickH-Index: 31
Last. Alan R. SpitzerH-Index: 44
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Source
#1Ibrahim M. Shokry (Ross University School of Veterinary Medicine)H-Index: 3
#2John J. Callanan (Ross University School of Veterinary Medicine)H-Index: 6
Last. Rui Tao (FAU: Florida Atlantic University)H-Index: 3
view all 4 authors...
3,4-Methylenedioxymethamphetamine (MDMA; ecstasy) toxicity may cause region-specific changes in serotonergic mRNA expression due to acute serotonin (5-hydroxytryptamine; 5-HT) syndrome. This hypothesis can be tested using in situ hybridization to detect the serotonin 5-HT2A receptor gene htr2a. In the past, such procedures, utilizing radioactive riboprobe, were difficult because of the complicated workflow that needs several days to perform and the added difficulty that the technique required th...
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#1Veeral N. Tolia (Baylor University Medical Center)H-Index: 10
#2Stephen W. Patrick (Vandy: Vanderbilt University)H-Index: 31
Last. Alan R. SpitzerH-Index: 44
view all 8 authors...
BackgroundThe incidence of the neonatal abstinence syndrome, a drug-withdrawal syndrome that most commonly occurs after in utero exposure to opioids, is known to have increased during the past decade. However, recent trends in the incidence of the syndrome and changes in demographic characteristics and hospital treatment of these infants have not been well characterized. MethodsUsing multiple cross-sectional analyses and a deidentified data set, we analyzed data from infants with the neonatal ab...
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