Alan Gevins
Elementary cognitive taskTemporal resolutionBrain activity and meditationDevelopmental psychologyStimulus (physiology)NeurophysiologyPattern recognition (psychology)Artificial intelligencePsychologyNeuroscienceCognitionNeurocognitivePattern recognitionCognitive psychologyWorking memoryEvoked potentialTask (project management)Computer scienceSpatial memoryElectroencephalographyAudiologyEvent-related potential
Publications 64
#1Alan GevinsH-Index: 39
#2Cynthia S. ChanH-Index: 6
Last. Lita Sam-VargasH-Index: 4
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Objective Extend a method to track neurophysiological pharmacodynamics during repetitive cognitive testing to a more complex “lifelike” task.
#1Stuart F. Quan (Harvard University)H-Index: 82
#2Kristen Hedger Archbold (UA: University of Arizona)H-Index: 16
Last. James L. Goodwin (UA: University of Arizona)H-Index: 33
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Study Objective. To determine the impact of sleep disordered breathing (SDB) in children on neurocognitive function 5 years later. Design, Setting, and Participants. A subgroup of 43 children from the Tucson Children’s Assessment of Sleep Apnea Study (TuCASA) who had SDB (RDI > 6 events/hour) at their initial exam (ages 6-11 years) were matched on the basis of age (within 1 year), gender and ethnicity (Anglo/Hispanic) to 43 children without SDB (Control, RDI < 4 events/hour). The Sustained Worki...
8 CitationsSource
#1Clete A. Kushida (Stanford University)H-Index: 72
#2Deborah A. Nichols (Stanford University)H-Index: 10
Last. William C. Dement (Stanford University)H-Index: 113
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STUDY OBJECTIVE: To determine the neurocognitive effects of continuous positive airway pressure (CPAP) therapy on patients with obstructive sleep apnea (OSA). DESIGN, SETTING, AND PARTICIPANTS: The Apnea Positive Pressure Long-term Efficacy Study (APPLES) was a 6-month, randomized, double-blind, 2-arm, sham-controlled, multicenter trial conducted at 5 U.S. university, hospital, or private practices. Of 1,516 participants enrolled, 1,105 were randomized, and 1,098 participants diagnosed with OSA ...
221 CitationsSource
#1Alan GevinsH-Index: 39
#2Cynthia S. ChanH-Index: 6
Last. Lita Sam-VargasH-Index: 4
view all 3 authors...
In three studies, EEGs from three groups of participants were recorded during progressively more real world situations after drinking alcoholic beverages that brought breath alcohol contents near the limit for driving in California 30 minutes after drinking. A simple equation that measured neurophysiological effects of alcohol in the first group of 15 participants performing repetitive cognitive tasks was applied to a second group of 15 operating an automobile driving simulator, and to a third g...
15 CitationsSource
#1Alan GevinsH-Index: 39
#2Linda K. McEvoyH-Index: 66
Last. Aaron B. IlanH-Index: 7
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Objective Assess individual-subject long-term and within-day variability of a combined behavioral and EEG test of working memory.
19 CitationsSource
#1Alan GevinsH-Index: 39
#2Aaron B. IlanH-Index: 7
Last. Cynthia S. ChanH-Index: 6
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An initial standardized approach for combining neuropsychological and neurophysiological measures in order to assess the neurocognitive effects of drugs in groups and individuals is introduced. Its application is illustrated with sedatives, antiepileptic drugs, psychostimulants, antihistamines, and intoxicants. Task performance, electroencephalography, and evoked potential measures during computerized attention and memory testing that are most sensitive to drug effects are identified in a sample...
13 CitationsSource
#1Stuart F. Quan (UA: University of Arizona)H-Index: 82
#2Cynthia S. ChanH-Index: 6
Last. Clete A. Kushida (Stanford University)H-Index: 72
view all 17 authors...
303 Obstructive Sleep Apnea and Neurocognitive Performance—Quan et al INTRODUCTION The obstructive sleep apnea syndrome (OSA) is a potentially life-threatening sleep related breathing disorder estimated in 1993 to affect 4% of men and 2% of women in the United States between the ages of 30 and 60 years.1 The prevalence appears to be increasing with trends towards higher rates of obesity.2 Recent data from several large observational cohort studies provide strong evidence that untreated OSA is an...
136 CitationsSource
#1Alan GevinsH-Index: 39
#2Michael E. SmithH-Index: 39
Last. Gordon AbrahamH-Index: 1
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Objective An automated cognitive neurophysiological test is presented that characterizes how an individual was affected by a drug or treatment. The test calculates sub-scores for working memory task performance, cortical activation, and alertness, and combines the sub-scores into an overall score.
14 CitationsSource
#1Alan Gevins (MSU: Michigan State University)H-Index: 39
#2Aaron B. IlanH-Index: 7
Last. Ruth O'Hara (Stanford University)H-Index: 50
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Background: The development of better treatments for brain diseases of the elderly will necessitate more sensitive and efficient means of repeatedly assessing an individual’s neuroc
5 CitationsSource
#1Kimford J. Meador (Emory University)H-Index: 93
#2Alan GevinsH-Index: 39
Last. David W. Loring (Emory University)H-Index: 77
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SUMMARY Purpose: Brivaracetam (BRV) is a new anticonvulsant under development. Although BRV is an analog of levetiracetam (LEV), in addition to being an SV2A ligand, it also inhibits sodium channels in a voltage-dependent manner. The cognitive effects of BRV are uncertain. Methods: A randomized, double-blind, placebo-controlled, four-way cross-over design was employed in 16 healthy volunteers comparing acute dosing (i.e., two doses) of BRV 10 mg, LEV 500 mg, lorazepam (LZP) 2 mg, and placebo. Th...
63 CitationsSource