Pravin Shende
Narsee Monjee Institute of Management Studies
Nuclear chemistryNanoparticleBiosensorControlled releaseNanotechnologyBioavailabilityNanocarriersLiposomeChemistryMaterials scienceCyclodextrinDrug deliveryDrugStem cellChemical engineeringCancer researchPolymerMedicineZeta potentialPharmacology
112Publications
15H-index
751Citations
Publications 110
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#1Pravin Shende (Narsee Monjee Institute of Management Studies)H-Index: 15
#2Sahil Gandhi (Narsee Monjee Institute of Management Studies)
Abstract Conventional chemotherapy treatment for cancer tends to show severe systemic toxicities like hair loss (alopecia), anemia, diarrhea, edema and loss of appetite. Radiopharmaceuticals emerge in the management and treatment of cancer since last two decades due to their ability of emitting radiations which aids in visualizing tissues or infected cells accurately in human body with minimal toxicity. Currently, many radionuclides are identified or developed with specific biological activity t...
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#1Drashti Desai (Narsee Monjee Institute of Management Studies)H-Index: 3
#2Pravin Shende (Narsee Monjee Institute of Management Studies)H-Index: 15
Abstract null null The present study aimed to complex neuropeptide Y with hydroxypropyl β-cyclodextrin (HPβ-CD) and optimize using central composite design with different levels of neuropeptide Y and HPβ-CD. The validated inclusion nanocomplex (formulation CN) showed monodispersed particle size of 330.019 ± 4.08 nm, % entrapment efficiency of 84.68 ± 5.47 and in-vitro neuropeptide Y release from the complex of 85.16 ± 6.13% for 24 h. Formulation CN was found to be stable for 3 months under two c...
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#1Mansi Waghchaure (Narsee Monjee Institute of Management Studies)H-Index: 1
#2Sharayu Govardhane (Narsee Monjee Institute of Management Studies)
Last. Pravin Shende (Narsee Monjee Institute of Management Studies)H-Index: 15
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The main objective of the present study was to prepare and evaluate dissolvable microneedle patch containing nanoparticles of tetanus toxoid without the use of any adjuvant and its immunopotentiation activity. Immunization with microneedles is a novel approach in vaccines delivery with advantages such as convenience, simple, and non-invasive therapy. The gelatin nanoparticles were prepared by a layer-by-layer coating method using polystyrene sulfonate (PSS), polyallylamine hydrochloride (PLA), a...
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#1Nazneen Pathan (Narsee Monjee Institute of Management Studies)H-Index: 1
#2Pravin Shende (Narsee Monjee Institute of Management Studies)H-Index: 15
P-Glycoprotein serves as a gatekeeper in the blood-brain-barrier wherein, it shows a vital part in the elimination of xenobiotics, drugs, foreign molecules etc. and guards the central nervous system from infections and external toxic molecules by functioning as an efflux transporter. It plays an essential role in various brain-related conditions like Parkinsonism, Alzheimer's disease, depression, cancer, etc. and terminates the entry of therapeutic agents across blood-brain-barrier which remains...
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AbstractThis research work intended to prepare and characterize novel dendrimer-based biosensors with an improved response for the detection of glucose in saliva. The nanoparticles of Fe3O4, a core...
2 CitationsSource
#1Nazneen Pathan (Narsee Monjee Institute of Management Studies)H-Index: 1
#2Pravin Shende (Narsee Monjee Institute of Management Studies)H-Index: 15
Abstract Smart polymeric materials and hydrogels derived from acrylate, epoxy resins, etc. mimic the healing ability of natural organisms and biological cells by showing shape memory and tissue regenerative properties wherein, the healing ability in some of the materials is triggered by external stimuli like temperature, pH and light. This article provides an overview of various conceptual strategies and chemical and mechanical interactions involved in the different types of biomimetic self-heal...
1 CitationsSource
The aim of the present study was to explore the synergistic effect of nitric oxide, chitosan and gelatin-grafted cotton for wound healing. Grafted cottons were prepared by etherification process where hydroxyl group of chitosan and hydroxyl group of cotton formed ether bond with dimethylol dihydroxy ethylene urea. Photomicrography and SEM studies showed the changes in cotton fibres before and after grafting process. Chitosan-grafted cotton (formulation F1) and chitosan-gelatin-grafted cotton (fo...
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#1Sharayu Govardhane (Narsee Monjee Institute of Management Studies)
#2Pravin Shende (Narsee Monjee Institute of Management Studies)H-Index: 15
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#1Anjali Takke (Narsee Monjee Institute of Management Studies)H-Index: 2
#2Pravin Shende (Narsee Monjee Institute of Management Studies)H-Index: 15
Abstract Aims Silibinin offers potential anticancer effect with less aqueous solubility and high permeability. The present study aimed to develop biocompatible magnetic-core-based nanopolymeric carriers of poly (D, l -lactide-co-glycolic) acid (PLGA) encapsulated silibinin for the sustained release action on renal cancerous cell. Main methods The synthesized iron oxide nanoparticles were prepared by precipitation method via encapsulation of silibinin in PLGA network using double emulsion method....
1 CitationsSource