Zenya Saito
Jikei University School of Medicine
AirwayInternal medicineRadiologySurgeryPathologyOncologyUnivariate analysisRenal functionDoseIntensive care medicineProspective cohort studyMedical recordAdverse effectObservational studyHepatitisBudesonideLung cancerGlycyrrhizinChemotherapyCOPDCorticosteroidRespiratory failurePerformance statusSynovial sarcomaExacerbationMechanical ventilationPemetrexedRenal cell carcinomaHigh-resolution computed tomographyCarcinomaInfiltration (medical)Standard treatmentPneumoniaErlotinibAlanine transaminaseKidney diseaseSystemic diseaseDiscontinuationIntubationPrednisoneMetastasisThoracoscopyMEDLINEPleural effusionLymphSputum cultureMetastatic carcinomaSingle CenterIgG4-related diseaseNephrectomyFibrosisOxygen therapyTuberculosis diagnosisUrsodeoxycholic acidTuberculosisAtelectasisDocetaxelRegimenIdiopathic bronchiectasisExudative pleural effusionDrug induced hepatotoxicityParietal PleuraTraction bronchiectasisInterferon-gamma Release TestsCryptogenic Organizing PneumoniaHepatoprotective DrugsAnti tuberculosisCoronavirus disease 2019 (COVID-19)Follow up studiesIn patientLate phaseTreatment outcomePleural metastasisLow doseRetrospective analysisChest ctAnesthesiaIncidence (epidemiology)Proportional hazards modelRespiratory systemClinical trialComputed tomographyTerm (time)MedicineGastroenterologyPharmacology
12Publications
5H-index
20Citations
Publications 12
Newest
Abstract We present a case of a 69-year-old man who had localized pleural metastasis without other organ metastases after nephrectomy for right renal cell carcinoma (RCC). He complained of respiratory symptoms for more than two years after the operation and was confirmed to have right pleural effusion and multiple pleural masses on computed tomography (CT). There were no abnormal findings in the other organs, but the pleural mass gradually increased in size on CT. We suspected malignant tumors s...
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#1Zenya SaitoH-Index: 5
#2Masahiro YoshidaH-Index: 42
Last. Kazuyoshi KuwanoH-Index: 58
view all 6 authors...
Source
#1Zenya SaitoH-Index: 5
#2Masahiro YoshidaH-Index: 42
Last. Kazuyoshi Kuwano (Jikei University School of Medicine)H-Index: 58
view all 6 authors...
BACKGROUND Chronic obstructive pulmonary disease (COPD) typically includes neutrophilic airway inflammation and eosinophilic inflammation in some cases. Inhaled corticosteroid (ICS) suppresses eosinophilic inflammation of the airway and reduces acute exacerbation (AE). The present study investigated the relationship between ICS and AE in patients with COPD classified by blood eosinophil counts. METHODS Overall, 244 patients with COPD were retrospectively evaluated between 2014 and 2017 and class...
1 CitationsSource
#1Kentaro TamuraH-Index: 1
#2Saiko NishiokaH-Index: 2
Last. Kazuyoshi KuwanoH-Index: 58
view all 5 authors...
This is a first observational study of four patients on steroid pulse therapy for secondary organizing pneumonia with respiratory failure due to the Coronavirus Disease 2019 (COVID-19) in our hospital. All patients needed invasive mechanical ventilation and had bimodal worseness of their respiratory status with organizing pneumonia after intubation. All cases could successfully discontinue oxygen therapy without any severe adverse events after this pulse therapy. Although few previous reports sh...
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#1Zenya SaitoH-Index: 5
#2Masahiro YoshidaH-Index: 42
Last. Kazuyoshi Kuwano (Jikei University School of Medicine)H-Index: 58
view all 5 authors...
Abstract Here we describe the case of a 78-year-old man with respiratory failure and right pleural effusion. Computed tomography showed right pleural effusion with pleural calcification, tumor-like shadows induced by passive atelectasis, and enlarged mediastinal lymph nodes. Positron emission tomography showed right pleural thickening, rounded atelectasis, and enlarged mediastinal lymph nodes, without fluid accumulation in other organs. The pleural effusion showed lymphocyte-dominated exudates w...
1 CitationsSource
#1Kentaro Tamura (Jikei University School of Medicine)H-Index: 1
#2Saiko Nishioka (Jikei University School of Medicine)H-Index: 2
Last. Kazuyoshi Kuwano (Jikei University School of Medicine)H-Index: 58
view all 5 authors...
Although some prospective studies provided the evidence of corticosteroids for critically ill patients with COVID-19, the optimal dosage or timing of corticosteroids is still unknown. This is a case series of four patients on methyl-prednisolone pulses for the late phase of Coronavirus disease 2019 (COVID-19) with respiratory failure in our hospital. All patients needed invasive mechanical ventilation and had bimodal worseness of their respiratory status with consolidation and volume loss after ...
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#1Nayuta Saito (Jikei University School of Medicine)H-Index: 10
#2Yutaka Yoshii (Jikei University School of Medicine)H-Index: 10
Last. Kazuyoshi Kuwano (Jikei University School of Medicine)H-Index: 58
view all 10 authors...
Dosages of anti-tuberculosis (TB) drugs are recommended to be adjusted according to renal function for patients complicated with chronic kidney disease (CKD). However, the efficacy and safety outcomes of such renal function-based dosage adjustments are not fully elucidated. We retrospectively reviewed cases of pulmonary TB susceptible to first-line drugs that were treated at Jikei University Daisan Hospital between 2005 and 2014 with standard regimens based on dosage adjustments according to ren...
3 CitationsSource
#1Zenya Saito (Jikei University School of Medicine)H-Index: 5
#2Yugo Kaneko (Jikei University School of Medicine)H-Index: 3
Last. Kazuyoshi Kuwano (Jikei University School of Medicine)H-Index: 58
view all 9 authors...
Relapse of cryptogenic organizing pneumonia (COP) may lead to poor long-term prognosis and necessitates multiple rounds of steroid treatment with potential adverse effects. The objective of this study is to identify predictive factors of COP relapse by comparing demographic and clinical variables between relapse and non-relapse groups. During 2008–2013, 33 COP patients were treated, of which 23 (69.7%) and 10 patients (30.3%) were assigned to the non-relapse and relapse group, respectively. From...
4 CitationsSource
#1Zenya Saito (Jikei University School of Medicine)H-Index: 5
#2Yugo Kaneko (Jikei University School of Medicine)H-Index: 3
Last. Kazuyoshi Kuwano (Jikei University School of Medicine)H-Index: 58
view all 11 authors...
Background The effectiveness of hepatoprotective drugs for DIH (drug induced hepatotoxicity) during tuberculosis treatment is not clear. We evaluated the effectiveness of hepatoprotective drugs by comparing the period until the normalization of hepatic enzymes between patients who were prescribed with the hepatoprotective drugs after DIH was occurred and patients who were not prescribed with the hepatoprotective drugs.
4 CitationsSource
3 CitationsSource