Naohiro Oda
Okayama University
CancerInternal medicineRadiologyPathologyOncologyInterleukin 23Retrospective cohort studyAdverse effectImmunologyClinical endpointFEV1/FVC ratioLung cancerExacerbationLungT790MErlotinibEpidermal growth factor receptorPembrolizumabGefitinibAfatinibLymph nodeElastasePD-L1AdenocarcinomaNon small cellImmune checkpoint inhibitorsVital capacityMedicineImmune systemGastroenterology
45Publications
8H-index
152Citations
Publications 46
Newest
#1Naohiro OdaH-Index: 8
Last. Ichiro TakataH-Index: 15
view all 4 authors...
A 43-year-old Chinese woman was referred to our hospital because of an abnormal shadow on a chest radiograph. The patient had come to Japan from China 4 weeks previously for technical intern training. She had never smoked and had no medical history of note. She had a mild cough but no fever, fatigue
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#1Naohiro OdaH-Index: 8
Last. Ichiro TakataH-Index: 15
view all 8 authors...
COVID-19 in cancer patients on immunosuppressive agents for the treatment of immune-related adverse events of immune checkpoint inhibitors can rapidly deteriorate. The combination therapy with methylprednisolone, baricitinib, and remdesivir may be effective for critical COVID-19, and further clinical trials are warranted.
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#1Daisuke Morichika (Okayama University)H-Index: 8
#2Akihiko Taniguchi (Okayama University)H-Index: 10
Last. Masayuki Hanaoka (Shinshu University)H-Index: 28
view all 15 authors...
Background IL-33, which is known to induce type 2 immune responses via group 2 innate lymphoid cells, has been reported to contribute to neutrophilic airway inflammation in chronic obstructive pulmonary disease. However, its role in the pathogenesis of emphysema remains unclear. Methods We determined the role of interleukin (IL)-33 in the development of emphysema using porcine pancreas elastase (PPE) and cigarette smoke extract (CSE) in mice. First, IL-33-/- mice and wild-type (WT) mice were giv...
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#1Naohiro OdaH-Index: 8
#2Takahiro TakiH-Index: 1
Last. Ichiro TakataH-Index: 15
view all 4 authors...
Abstract Herein, we report the case of a 74-year-old man diagnosed with Legionella pneumonia detected by Loop-Mediated Isothermal Amplification (LAMP) method, which was suspected to have been transmitted from the potting soil. Legionella longbeachae was identified in the sputum culture. The patient was intubated and maintained on mechanical ventilation. Antimicrobial therapy with azithromycin was also administered. His symptoms were resolved and he was discharged after 26 days of hospitalization...
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#2Naohiro OdaH-Index: 8
Last. Nobuaki Miyahara (RMIT: RMIT University)H-Index: 33
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Abstract Cryptococcosis is an invasive mycosis that has become increasingly prevalent in immunocompromised patients. Pregnant women are also one of the risk populations for cryptococcosis. Reversal of Th2 to Th1 response following resolution of immunosuppression during the postpartum period can lead to overt clinical manifestations of a previously silent infection, resembling an immune reconstitution inflammatory syndrome. Here, we report a case of a 30-year-old woman who had an exacerbation of ...
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#1Nobuaki Ochi (Kawasaki Medical School)H-Index: 16
#2Eiki Ichihara (Okayama University)H-Index: 21
Last. Katsuyuki Kiura (Okayama University)H-Index: 68
view all 14 authors...
BACKGROUND Immune checkpoint inhibitors (ICIs) are essential for treatment of various malignancies, including non-small-cell lung cancer (NSCLC). Recently, several studies have shown that the gut microbiome plays an important role in ICI treatment of solid cancers, and antibiotic (ATB) use had a negative impact on the outcomes of ICI treatment via dysbiosis in the gut. However, whether this is applicable to NSCLC remains unclear. The impact of ATBs based on PD-L1 expression also remains unclear....
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#1Naohiro Oda (Okayama University)H-Index: 8
#2Masahiro Tabata (Okayama University)H-Index: 34
Last. Katsuyuki Kiura (Okayama University)H-Index: 68
view all 11 authors...
Mucinous cystic neoplasm (MCN) of the pancreas is a rare cystic tumor occurring in the pancreatic body and tail in young to middle-aged women that is pathologically characterized by an ovarian-like stroma. Chemotherapy for recurrent/advanced pancreatic MCN has been based on chemotherapy regimens for pancreatic ductal adenocarcinoma, but the prognosis is poor. We herein report a 37-year-old woman with pancreatic mucinous cystadenocarcinoma with liver metastasis that responded dramatically to carb...
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#1Naofumi Hara (Okayama University)H-Index: 5
#2Eiki Ichihara (Okayama University)H-Index: 21
Last. Katsuyuki Kiura (Okayama University)H-Index: 68
view all 13 authors...
OBJECTIVES The programmed death-ligand 1 (PD-L1) tumor proportion score (TPS) in tumor tissue samples is an established clinical biomarker for non-small cell lung cancer (NSCLC). However, the significance of PD-L1 expression in other types of samples has not been fully investigated. PATIENTS AND METHODS We conducted a multicenter retrospective cohort study of advanced NSCLC patients who received ICI treatment during the clinical course and investigated the effects of ICIs according to PD-L1 expr...
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#1Shigeru Tanzawa (Teikyo University)H-Index: 3
#2Sunao UshijimaH-Index: 5
Last. Nobuhiko Seki (Teikyo University)H-Index: 17
view all 44 authors...
Background:Based on the results of the PACIFIC study, chemoradiotherapy followed by 1-year consolidation therapy with durvalumab was established as the standard of care for unresectable, locally ad...
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