Patrick Y. Wuethrich
University of Bern
UrologySurgeryRandomized controlled trialCystectomyUrinary diversionMEDLINEUrinary bladderNorepinephrine (medication)Blood transfusionBladder cancerFentanylBupivacaineRegimenBladder substitutionIn patientPerioperativeAnesthesiaMedicineComplication
76Publications
13H-index
545Citations
Publications 78
Newest
#1Marc A. Furrer (University of Melbourne)H-Index: 9
#2Janine Abgottspon (University of Bern)
Last. Patrick Y. Wuethrich (University of Bern)H-Index: 13
view all 8 authors...
OBJECTIVE To assess if uninterrupted anticoagulant agents' administration affects blood loss and blood transfusion during open radical cystectomy (RC) and urinary diversion. PATIENTS AND METHODS We conducted an observational single-centre cohort study of a consecutive series of 1430 RC patients, between 2000 and 2020. Blood loss was depicted according to body weight and duration of surgery (mL/kg/h), and blood transfusion. The group 'with anticoagulant agents' was considered if surgery was perfo...
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#1Lukas M. Löffel (University of Bern)H-Index: 5
#2Robert G. Hahn (KI: Karolinska Institutet)H-Index: 54
Last. Patrick Y. Wuethrich (University of Bern)H-Index: 13
view all 4 authors...
Background The intraoperative effect of 20% albumin on plasma volume during surgery involving major blood loss has not been explored extensively due to methodological difficulties. Crystalloids poorly expand the plasma volume, and using a colloid might then be a way to avoid fluid overload. As doubts have been raised about synthetic colloids, albumin solutions are currently used more extensively. This study presents a methodological development showing how plasma volume expansion can be studied ...
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#1Christian M. Beilstein (University of Bern)H-Index: 4
Last. Patrick Y. WuethrichH-Index: 13
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#1Dominique Engel (University of Bern)H-Index: 2
#2Lukas M. Löffel (University of Bern)H-Index: 5
Last. Robert G. Hahn (KI: Karolinska Institutet)H-Index: 54
view all 4 authors...
Background. Postoperative elevation of plasma creatinine is a frequent complication to major surgery. A rise by 50% fulfils the criterion for Acute Kidney Injury. We studied the relationship between concentrated urine before surgery, which is a sign of dehydration or chronically low intake of water, and the perioperative change in plasma creatinine. Methods. The creatinine concentration was measured in plasma and urine just before and at 6 h, 1 day, and 2 days after major abdominal surgery in a ...
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#1Dominique Engel (University of Bern)H-Index: 2
#2Christian M. Beilstein (University of Bern)H-Index: 4
Last. Patrick Y. Wuethrich (University of Bern)H-Index: 13
view all 7 authors...
Open radical cystectomy is associated with a substantial rate of perioperative blood transfusion. Early detection of potentially modifiable perioperative factors could reduce the need for perioperative blood transfusion and thus positively impact the outcome. We conducted an observational, single-center cohort study of 1168 patients undergoing cystectomy. Perioperative blood transfusion was defined as the need for packed red blood cells and/or fresh frozen plasma units within the first 24 h afte...
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#1Marc A. Furrer (University of Bern)H-Index: 9
#2Fiona C. Burkhard (University of Bern)H-Index: 51
Last. Benjamin Thomas (University of Melbourne)H-Index: 6
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#1Robert G. Hahn (KI: Karolinska Institutet)H-Index: 54
#2Patrick Y. Wuethrich (University of Bern)H-Index: 13
Last. Joachim Zdolsek (Linköping University)H-Index: 12
view all 3 authors...
BACKGROUND Trends in non-invasive measurements of blood hemoglobin (Hb) may be useful for identifying the need for transfusion in the perioperative period. METHODS Crystalloid fluid (5-20 mL/kg) was administered intravenously or by mouth to 30 volunteers and 33 surgical patients in five non-randomized clinical studies where Hb was measured on 915 occasions by non-invasive (Radical-7™) and invasive methodology. The hemodilution curves were compared by volume kinetic analysis and linear regression...
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#2Urs E. StuderH-Index: 85
Last. Fiona C. BurkhardH-Index: 51
view all 3 authors...
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#1Lukas M. Löffel (University of Bern)H-Index: 5
#2Dominique Engel (University of Bern)H-Index: 2
Last. Patrick Y. Wuethrich (University of Bern)H-Index: 13
view all 3 authors...
Source
#1John-Patrik Burkhard (University of Bern)H-Index: 1
#2Jelena Pfister (University of Bern)
Last. Patrick Y. Wuethrich (University of Bern)H-Index: 13
view all 11 authors...
Objectives The aim of this study was to determine the influence of perioperative fluid management and administration of vasopressors on early surgical revision and flap-related complications in free tissue transfer. Materials and methods Intraoperative amount of fluid and of vasopressors, relevant perioperative parameters, and comorbidities were recorded in 131 patients undergoing head and neck microvascular reconstruction and compared with early surgical complications, defined as interventions ...
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