Caroline Lafond
University of Rennes
Quality assuranceRadiologyArtificial intelligenceImage registrationPattern recognitionMedical physicsRadiation treatment planningProstateProstate cancerRectumPlanned DosePopulationNuclear medicinePlanning target volumeVolumetric modulated arc therapyAdaptive radiotherapyHead and neckMathematicsComputer scienceRadiation therapyMedicineImage-guided radiation therapy
113Publications
15H-index
613Citations
Publications 107
Newest
#2A. BarateauH-Index: 5
Last. Oscar AcostaH-Index: 21
view all 10 authors...
Several approaches have been proposed to generate pseudo computed tomography (pCT) from MR images for radiotherapy dose calculation. Quantification of errors in pCT has been reported using global scores disregarding spatial heterogeneity. The aim of this work was to propose a population voxel-based workflow allowing the local assessment of errors in the generation of pCTs from MRI. For the voxel-wise analysis to be anatomically meaningful, a robust customized inter-patient non-rigid registration...
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#1J. BellecH-Index: 4
#2Antoine Simon (French Institute of Health and Medical Research)H-Index: 17
Last. R. de Crevoisier (French Institute of Health and Medical Research)H-Index: 20
view all 8 authors...
Introduction et but de l’etude La radiotherapie ablative pour la tachycardie ventriculaire refractaire est une application emergente de radiotherapie stereotaxique qui consiste a delivrer une dose ablative de 25 Gy en une seance unique au niveau d’une region cardiaque arythmogene. Elle implique la definition d’un volume cible previsionnel complexe integrant la combinaison des battements cardiaques et des mouvements respiratoires. L’objectif de cette etude etait d’evaluer l’impact geometrique des...
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#1A. Barateau (French Institute of Health and Medical Research)H-Index: 5
#2Renaud de Crevoisier (French Institute of Health and Medical Research)H-Index: 28
Last. Caroline LafondH-Index: 15
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PURPOSE Anatomical variations occur during head and neck (H&N) radiotherapy treatment. kV cone-beam computed tomography (CBCT) images can be used for daily dose monitoring to assess dose variations owing to anatomic changes. Deep learning methods (DLMs) have recently been proposed to generate pseudo-CT (pCT) from CBCT to perform dose calculation. This study aims to evaluate the accuracy of a DLM and to compare this method with three existing methods of dose calculation from CBCT in H&N cancer ra...
2 CitationsSource
#1Caroline Lafond (French Institute of Health and Medical Research)H-Index: 15
#2A. Barateau (French Institute of Health and Medical Research)H-Index: 5
Last. Renaud de Crevoisier (French Institute of Health and Medical Research)H-Index: 28
view all 10 authors...
Background: A rectal sub-region (SRR) has been previously identified by voxel-wise analysis in the inferior-anterior part of the rectum as highly predictive of rectal bleeding (RB) in prostate cancer radiotherapy. Translating the SRR to patient-specific radiotherapy planning is challenging as new constraints have to be defined. A recent geometry-based model proposed to optimize the planning by determining the achievable mean doses (AMDs) to the organs at risk (OARs), taking into account the over...
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#1J. BellecH-Index: 4
#2F. Arab-CeschiaH-Index: 1
Last. Enrique ChajonH-Index: 13
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BACKGROUND: The internal target volume (ITV) approach and the mid-ventilation (MidV) concept are the two main respiratory motion-management strategies under free breathing. The purpose of this work was to compare the actual in-treatment target coverage during volumetric modulated arctherapy (VMAT) delivered through both ITV-based and MidV-based planning target volume (PTV) and to provide knowledge in choosing the optimal PTV for stereotactic body radiotherapy (SBRT) for lung lesions. METHODS AND...
4 CitationsSource
#1A. Largent (French Institute of Health and Medical Research)H-Index: 5
#2A. Barateau (French Institute of Health and Medical Research)H-Index: 5
Last. Renaud de Crevoisier (French Institute of Health and Medical Research)H-Index: 28
view all 12 authors...
Purpose Deep learning methods (DLMs) have recently been proposed to generate pseudo-CT (pCT) for magnetic resonance imaging (MRI) based dose planning. This study aims to evaluate and compare DLMs (U-Net and generative adversarial network [GAN]) using various loss functions (L2, single-scale perceptual loss [PL], multiscale PL, weighted multiscale PL) and a patch-based method (PBM). Methods and Materials Thirty-nine patients received a volumetric modulated arc therapy for prostate cancer (78 Gy)....
12 CitationsSource
#1A. LargentH-Index: 5
#2A. BarateauH-Index: 5
Last. R. de CrevoisierH-Index: 20
view all 10 authors...
1 CitationsSource
#1Jean-Claude Nunes (French Institute of Health and Medical Research)H-Index: 14
#2A. Largent (University of Rennes)H-Index: 5
Last. Oscar Acosta (French Institute of Health and Medical Research)H-Index: 21
view all 13 authors...
Introduction et but de l’etude Differentes methodes d’apprentissage peuvent etre utilisees pour generer des pseudo-scanographies a partir d’IRM ou de tomographies coniques (cone beam computed tomography, CBCT), permettant un calcul de distribution de dose. L’objectif est d’evaluer des methodes d’apprentissage pour generer des pseudo-scanographies a partir d’IRM et de tomographies coniques. Materiel et methodes Trente-neuf patients ayant une radiotherapie conformationnelle avec modulation d’inten...
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#1C. Le DeroffH-Index: 1
#2J. BellecH-Index: 4
Last. Caroline Lafond (French Institute of Health and Medical Research)H-Index: 15
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Introduction et but de l’etude L’objectif de cette etude etait d’obtenir des cartographies tridimensionnelles personnalisees des doses delivrees par l’imagerie en radiotherapie guidee par l’image. Materiel et methodes Ce travail est issu du projet AID-IGRT (ANR-15-CE19-0009) visant a developper un outil de calcul tridimensionnele des doses dues a l’image par simulation Monte Carlo. Toutes les modalites de radiotherapie guidee par l’image courantes ont ete etudiees : imageries tridimensionnelles,...
1 CitationsSource
#1Joël Castelli (French Institute of Health and Medical Research)H-Index: 17
#2Antoine Simon (French Institute of Health and Medical Research)H-Index: 17
Last. R. de Crevoisier (French Institute of Health and Medical Research)H-Index: 20
view all 8 authors...
Introduction et but de l’etude Une seule planification en cas de radiotherapie conformationnelle avec modulation d’intensite (RCMI) pour une tumeur de la sphere ORL localement evoluee peut conduire a un « sous-dosage » tumoral du fait des variations anatomiques en cours d’irradiation. L’objectif de l’etude etait d’identifier tres precocement les patients ayant ce risque, pour leur proposer une strategie de radiotherapie adaptative. Materiel et methodes Trente-quatre patients ont ete pris en char...
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