Elisabeth Bendstrup
Aarhus University Hospital
Internal medicineRadiologySurgeryPathologyIntensive care medicinePhysical therapyAdverse effectFEV1/FVC ratioCOPDInterstitial lung diseaseLungIdiopathic pulmonary fibrosisDiseaseComorbidityPirfenidoneIn patientVital capacityMedicineCohortPulmonary function testingGastroenterology
Publications 221
#1Meena Kalluri (U of A: University of Alberta)H-Index: 10
#2Fabrizio Luppi (University of Milano-Bicocca)H-Index: 25
Last. Elisabeth Bendstrup (Aarhus University Hospital)H-Index: 26
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Patient-reported outcome measures (PROMs), tools to assess patient self-report of health status, are now increasingly used in research, care and policymaking. While there are two well-developed disease-specific PROMs for interstitial lung diseases (ILD) and idiopathic pulmonary fibrosis (IPF), many unmet and urgent needs remain. In December 2019, 64 international ILD experts convened in Erice, Italy to deliberate on many topics, including PROMs in ILD. This review summarises the history of PROMs...
#1S Tomassetti (UniFI: University of Florence)H-Index: 10
Last. Sissel Kronborg-White (AU: Aarhus University)H-Index: 5
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#1Ian Glaspole (Monash University)H-Index: 26
#2Francesco Bonella (University of Duisburg-Essen)H-Index: 32
Last. Elisabeth Bendstrup (Aarhus University Hospital)H-Index: 26
view all 9 authors...
BACKGROUND Idiopathic pulmonary fibrosis (IPF) predominantly affects individuals aged > 60 years who have several comorbidities. Nintedanib is an approved treatment for IPF, which reduces the rate of decline in forced vital capacity (FVC). We assessed the efficacy and safety of nintedanib in patients with IPF who were elderly and who had multiple comorbidities. METHODS Data were pooled from five clinical trials in which patients were randomised to receive nintedanib 150 mg twice daily or placebo...
#1Nils HoyerH-Index: 4
#2Henrik JessenH-Index: 1
Last. Saher B. ShakerH-Index: 22
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BACKGROUND AND OBJECTIVE Prediction of idiopathic pulmonary fibrosis (IPF) progression is vital for the choice and timing of treatment and patient follow-up. This could potentially be achieved by prognostic blood biomarkers of extracellular matrix (ECM) remodelling. METHODS Neoepitope biomarkers of types III and VI collagen turnover (C3M, C6M, PRO-C3 and PRO-C6) were measured in 185 patients with newly diagnosed IPF. Disease severity at baseline and progression over 6 months was assessed by lung...
#1Jesper Rømhild Davidsen (OUH: Odense University Hospital)H-Index: 11
#2Christian B. Laursen (University of Southern Denmark)H-Index: 12
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Background: Bronchiolitis obliterans syndrome (BOS) and restrictive allograft syndrome (RAS) are two distinct phenotypes of chronic lung allograft dysfunction (CLAD) in lung transplant (LTx) recipients. Contrary to BOS, RAS can radiologically present with a pleuroparenchymal fibroelastosis (PPFE) pattern. This study investigates lung ultrasound (LUS) to identify potential surrogate markers of PPFE in order to distinguish CLAD phenotype RAS from BOS. Methods: A prospective cohort study performed ...
Background Transbronchial cryobiopsies has become increasingly used in the diagnostic workup in patients suspected of having interstitial lung disease. The procedure is associated with less complications, morbidity and mortality compared to surgical lung biopsies although with a diagnostic yield that is not as high, but close to that of surgical lung biopsies. The aim of the present study was to describe the complications and diagnostic yield and their prognostic factors. Methods All patients un...
#1Anna-Maria Hoffmann-Vold (Oslo University Hospital)H-Index: 18
#2Elisabeth Bendstrup (Aarhus University Hospital)H-Index: 26
Last. Wim Wuyts (Katholieke Universiteit Leuven)H-Index: 35
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Objectives Interstitial lung disease is frequent in systemic sclerosis (SSc-ILD) and associates with significantly reduced quality of life. Here we aimed to analyse patient pathways, and experiences of patients and healthcare providers (HCPs) in order to identify unmet needs in the management of SSc-ILD patients. Methods Semi-structured qualitative interviews conducted in eight European countries looked at HCP (n=95) and patient perspective (n=47), using two sets of 70 research questions. Pre-di...
#1Vincent Cottin (University of Lyon)H-Index: 76
#2Elisabeth Bendstrup (Aarhus University Hospital)H-Index: 26
Last. Martin Kolb (McMaster University)H-Index: 63
view all 7 authors...
Methotrexate can induce subacute hypersensitivity pneumonitis, a potentially lethal condition that should lead to drug discontinuation; however, its use does not seem to be associated with increased risk of chronic fibrosing ILD in rheumatoid arthritishttps://bit.ly/3sCyjji
#1Argyris Tzouvelekis (University of Patras)H-Index: 28
#1Argyris Tzouvelekis (University of Patras)
Last. Demosthenes BourosH-Index: 73
view all 20 authors...
Background Currently there is major lack of agreement on the diagnostic and therapeutic management of patients with idiopathic pulmonary fibrosis (IPF) and lung cancer. Our aim was to identify variations in diagnostic and management strategies across different institutions and provide rationale for a consensus statement on this issue. Methods This was a joint-survey by European Respiratory Society (ERS) Assemblies 8, 11 and 12. The survey consisted of 25 questions. Results Four hundred and ninet...
2 CitationsSource
#1Manuela Funke-Chambour (University of Bern)H-Index: 6
#2Carlo Albera (UNITO: University of Turin)H-Index: 29
Last. Ganesh Raghu (UW: University of Washington)H-Index: 91
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Medical guidelines on diagnosis and management of relevant diseases aim to recommend clinical practice while standardising patient care. However, evidence-based guideline development is laborious and challenging, the recommendations require nuanced wording, and the optimal approach remains controversial. Footnotes This manuscript has recently been accepted for publication in the European Respiratory Journal . It is published here in its accepted form prior to copyediting and typesetting by our p...