Ivana Kholová
University of Eastern Finland
RadiologyPathologyCytologyImmunohistochemistryBiopsyColposcopyFine-needle aspirationBethesda systemCervical cancerCytopathologySalivary glandBethesda system for reporting thyroid cytopathologyMalignancyThyroid cancerParotid glandAtypiaSuspicious for MalignancySalivary gland neoplasmThyroidMedicine
Publications 45
#1Ivana KholováH-Index: 17
#2David Kalfert (First Faculty of Medicine, Charles University in Prague)H-Index: 7
Last. Marie Ludvíková (Charles University in Prague)H-Index: 14
view all 5 authors...
Follicular epithelial dysplasia (FED) is described as Hashimoto thyroiditis-related atypia and is thought to be a possible precancerous lesion. Dysplasia as an interface between normal state and carcinoma is described in a wide range of diseases and carcinogenesis chains. On the other hand, inflammation-related atypia and cancerogenesis is also widely studied. In this study, we retrospectively analyzed 91 specimens of thyroid gland surgical resections with FED during a 10-year-period at the univ...
#1Mikk Abram (UTA: University of Tampere)H-Index: 1
#2Roope Huhtamella (UTA: University of Tampere)H-Index: 1
Last. Ivana Kholová (UTA: University of Tampere)H-Index: 17
view all 6 authors...
INTRODUCTION Thyroid cytology is a widely accepted tool in the clinical triaging of nodular lesions. Cell blocks (CBs) can help in the diagnosis of atypical lesions, namely, thyroid Bethesda category of Atypia of undetermined significance/follicular lesion of undetermined significance (AUS/FLUS). METHODS In a series of 224 AUS/FLUS thyroid samples with CB, we studied CB cellularity and feasibility of 3 immunohistochemical markers (cytokeratin 19 [CK19], HBME-1, and galectin-3) apart and in combi...
1 CitationsSource
#1Markéta Horáková (Charles University in Prague)H-Index: 1
#2Sinikka PorreH-Index: 1
Last. Ivana KholováH-Index: 17
view all 6 authors...
OBJECTIVE Fine-needle aspiration (FNA) is a key diagnostic method in the evaluation of salivary gland lesions. Secondary tumors of salivary glands represent only 5% of all malignancies of major salivary glands. The goal of our study was to examine the cytological and clinical features of secondary tumors sampled by FNA. MATERIALS AND METHODS A series of 36 secondary tumors from the pathology departments of two university hospitals are presented. Clinical referrals to FNA, cytological features, i...
#2Heini HuhtalaH-Index: 58
Last. Ivana KholováH-Index: 17
view all 3 authors...
In the high-income countries the amount of cervical adenocarcinomas is on the rise. The pap smear sampling has a low sensitivity and a low specificity for endocervical malignancies and there are only a few cytomorphological features, that are specifically associated with glandular atypia. In this study, 298 pap smears of 60 patients with endocervical adenocarcinoma or adenocarcinoma in situ (AIS) and 30 patients with high grade intraepithelial lesion (HSIL) in histology were reviewed. The pap sm...
#1Derek B. Allison (UK: University of Kentucky)H-Index: 10
#2Alexander P. Smith (UK: University of Kentucky)
Last. Zahra Maleki (Johns Hopkins University)H-Index: 16
view all 22 authors...
BACKGROUND The Milan System for Reporting Salivary Gland Cytopathology (MSRSGC) has established distinct diagnostic categories for reporting cytopathological findings, and each is associated with a defined risk of malignancy (ROM). However, the ROM is applied at the overall category level and is not specific for particular morphological entities within a category. Here, the diagnostic performance of the MSRSGC for pleomorphic adenoma (PA) and Warthin tumor (WT) is reported. METHODS The pathology...
#1Elena Vigliar (University of Naples Federico II)H-Index: 18
#2Rima Cepurnaite (University of Naples Federico II)H-Index: 1
Last. Giancarlo Troncone (University of Naples Federico II)H-Index: 44
view all 63 authors...
BACKGROUND: To the authors' knowledge, the impact of the coronavirus disease 2019 (COVID-19) pandemic on cytopathology practices worldwide has not been investigated formally. In the current study, data from 41 respondents from 23 countries were reported. METHODS: Data regarding the activity of each cytopathology laboratory during 4 weeks of COVID-19 lockdown were collected and compared with those obtained during the corresponding period in 2019. The overall number and percentage of exfoliative a...
10 CitationsSource
IgG4-positive plasma cells in Hashimoto thyroiditis: IgG4-related disease or inflammation-related IgG4-positivity? Despite the interest of researchers in IgG4-related disease (IgG4-RD), many questions still remain unanswered regarding the thyroid gland. We aimed to clarify the relationship between IgG4-positive plasma cells and the histopathological pattern in the Hashimoto thyroiditis (HT) in a Finnish series. HT specimens (n=280) were retrieved from the Department of Pathology, Fimlab Laborato...
#1Lucie Dostalova (First Faculty of Medicine, Charles University in Prague)H-Index: 2
#2David Kalfert (First Faculty of Medicine, Charles University in Prague)H-Index: 7
Last. Jan Plzak (First Faculty of Medicine, Charles University in Prague)H-Index: 18
view all 11 authors...