S.C. Pant
Defence Research and Development Establishment
Internal medicineEndocrinologyPathologyHorticultureAlkaline phosphataseChemistryOxidative stressInhalationLungMalondialdehydeAntidoteInhalation exposureKidneySarinSulfur mustardSpleenToxicityToxicologyGlutathioneBiochemistryMedicineBiologyPharmacology
Publications 68
#2S.C. PantH-Index: 22
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In India agricultural marketing is governed by a set of public owned wholesale markets which were established during the colonial period under the APMC Act. The regulatory mechanism, which is more than 100 years old, no doubt, has put in place some good marketing practices.
#1Kalyani Chaubey (DRDE: Defence Research and Development Establishment)H-Index: 3
#2Syed Imteyaz Alam (DRDE: Defence Research and Development Establishment)H-Index: 18
Last. B.K. Bhattacharya (DRDE: Defence Research and Development Establishment)H-Index: 10
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Sarin is an organophosphorus (OP) chemical warfare agent which irreversibly inhibits acetylcholinesterase. Acute toxicity after sarin exposure is because of hyper activation of the nicotinic and muscarinic receptor. Survivors of sarin exposure often develop long-term neuropathology referred as OP ester-induced chronic neurotoxicity. However, the exact mechanism of chronic neurotoxicity is yet unknown. We studied proteomic changes in rat brain regions after 0.5 LD50 dose of sarin and investigated...
#1Bhavana Sant (DRDE: Defence Research and Development Establishment)H-Index: 2
#2P.V. Lakshmana Rao (DRDE: Defence Research and Development Establishment)H-Index: 1
Last. A.S.B. Bhasker (DRDE: Defence Research and Development Establishment)H-Index: 2
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Abstract Abrin is a potent plant toxin analogous to ricin that is derived from the seeds of Abrus precatorius plant. It belongs to the family of type II ribosome-inactivating proteins and causes cell death by irreversibly inactivating ribosomes through site-specific depurination. In this study we examined the in vivo nephrotoxicity potential of abrin toxin in terms of oxidative stress, inflammation, histopathological changes and biomarkers of kidney injury. Animals were exposed to 0.5 and 1.0 LD...
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