Kazuichi Okazaki
Kansai Medical University
Internal medicineRadiologyBalloonSurgeryPathologyImmunologyColitisPancreatitisAutoimmune pancreatitisPancreasDiseasePancreatic cancerIgG4-related diseaseFibrosisIn patientHepatologyGeneral surgeryMedicineBiologyGastroenterology
700Publications
85H-index
20.4kCitations
Publications 699
Newest
#1Annarosa Floreani (UNIPD: University of Padua)H-Index: 59
#2Sara De Martin (UNIPD: University of Padua)H-Index: 16
Last. M. E. Gershwin (UC Davis: University of California, Davis)H-Index: 53
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Introduction: Microbial antigens present in the intestine has been suggested as possible triggers of primary biliary cholangitis (PBC) and it has been demonstrated that the gut microbiome is modifi...
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#1Yuji Tanimura (Kansai Medical University)H-Index: 1
#2Toshiro Fukui (Kansai Medical University)H-Index: 22
Last. Kazuichi Okazaki (Kansai Medical University)H-Index: 85
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Although chemical-induced animal models of colorectal cancer (CRC) suggest a lot about the disease, more efforts are required to establish metastasis models. Azoxymethane (AOM) and dextran sodium sulfate (DSS)-treated (AOM/DSS) Crl:CD-1 mice were sacrificed after 10 or 20 weeks in our previous study, and most colon tumors exhibited intramucosal adenocarcinomas. Our observations were extended until 30 weeks to study a colitis-associated advanced CRC mouse model, and explore whether linker threoni...
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#1Natsuko Saito (Kansai Medical University)
#2Noriyo Yamashiki (Kansai Medical University)H-Index: 22
Last. Toshihito Seki (Kansai Medical University)H-Index: 32
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#1Kenji NotoharaH-Index: 41
#2Terumi KamisawaH-Index: 77
Last. Kazuichi Okazaki (Kansai Medical University)H-Index: 85
view all 29 authors...
The biopsy-based diagnosis of autoimmune pancreatitis (AIP) is difficult but is becoming imperative for pathologists due to the increased amount of endoscopic ultrasound-guided biopsy tissue. To cope with this challenge, we propose guidance for the biopsy diagnosis of type 1 AIP. This guidance is for pathologists and comprises three main parts. The first part includes basic issues on tissue acquisition, staining, and final diagnosis, and is intended for gastroenterologists as well. The second pa...
5 CitationsSource
#1Masaaki ShimataniH-Index: 17
Last. Kazuichi OkazakiH-Index: 85
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Endoscopic retrograde cholangiopancreatography (ERCP) is an endoscopic modality established for diagnosis and treatment of pancreaticobiliary diseases. However ERCP in patients with surgically altered anatomy (SAA) has been difficult, and more invasive therapies have been primarily selected. The development of balloon assisted endoscopes (BAEs) innovatively facilitated ERCP in such patients. Recent advances of BAEs and other devices greatly contributed to increasing success of ERCP using BAEs (B...
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#1Makoto Takaoka (Kansai Medical University)H-Index: 24
#2Masaaki Shimatani (Kansai Medical University)H-Index: 17
Last. Makoto Naganuma (Kansai Medical University)H-Index: 3
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Background and Aim A self-expandable metallic stent (SEMS) is commonly used for biliary stricture caused by pancreatic cancer. Covered SEMS may obstruct the cystic duct, causing acute cholecystitis. This study aimed to determine the outcomes of using a half-covered SEMS with an offset covered portion for preventing cystic duct obstruction. Methods Among 80 patients with half-covered SEMS placement for the treatment of pancreatic cancer-induced distal biliary stricture, 74 were followed up. The h...
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#1Atsushi Tanaka (Teikyo University)H-Index: 33
#2Mitsuru MoriH-Index: 36
Last. Kazuichi Okazaki (Kansai Medical University)H-Index: 85
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BACKGROUND/PURPOSE Epidemiological data on immunoglobulin G4-related sclerosing cholangitis (IgG4-SC) are scarce. METHOD We randomly selected healthcare facilities from a list of all facilities in Japan. The selection rate was determined according to a stratification based on the facility characteristics and scale. We sent questionnaires to the selected facilities enquiring about the number and sex of patients with IgG4-SC in 2018. Among responding facilities, we further inquired about the clini...
4 CitationsSource
#1Shunsuke Horitani (Kansai Medical University)H-Index: 1
#2Toshiro Fukui (Kansai Medical University)H-Index: 22
Last. Kazuichi Okazaki (Kansai Medical University)H-Index: 85
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BACKGROUND There is little known about stem cells in human non-neoplastic and neoplastic esophageal epithelia. We have demonstrated expression of linker threonine-phosphorylated Smad2/3 (pSmad2/3L-Thr), suggesting presence of stem-like cells in mouse esophageal epithelium, and identified presence of pSmad2/3L-Thr-positive cells that might function as cancer stem cells in mouse model of colorectal carcinoma. AIMS We explore whether pSmad2/3L-Thr can be used as a biomarker for stem cells of human ...
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#1Atsushi Masamune (Tohoku University)H-Index: 67
#2Kazuhiro Kikuta (Tohoku University)H-Index: 32
Last. Kazuichi Okazaki (Kansai Medical University)H-Index: 85
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OBJECTIVES To provide updated clinico-epidemiological information on chronic pancreatitis (CP) in Japan. METHODS We conducted a two-stage nationwide epidemiological survey; the number of CP patients was estimated in the first-stage survey, and their clinical features were examined in the second-stage survey. We surveyed patients with CP who had visited hospitals in 2016 and were diagnosed according to the Japanese diagnostic criteria 2009 (DC2009). Furthermore, we validated the new Japanese diag...
2 CitationsSource
#1Sohei Satoi (Kansai Medical University)H-Index: 31
#2Tomohisa Yamamoto (Kansai Medical University)H-Index: 20
Last. Kazuichi Okazaki (Kansai Medical University)H-Index: 85
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Objectives The objective of this study was to clarify the role of pancreatectomy for patients with resectable and borderline resectable pancreatic ductal adenocarcinoma aged 80 years or older using a nationwide audit by the Japan Pancreas Society. Methods Data were collected from 39 institutions from 2007 to 2014. The primary endpoint was overall survival, and secondary endpoints were surgical outcomes and predictive factors for prognosis. Results Data were obtained from 556 octogenarians who un...
2 CitationsSource