Paola Cassoni
University of Turin
CancerInternal medicineRadiologyEndocrinologySurgeryPathologyOncologyReceptorOxytocin receptorImmunohistochemistryBiopsyCarcinomaAnal cancerCancer researchRadiation therapyColorectal cancerBreast cancerCell growthMedicineBiology
Publications 359
#1Daniele PerloH-Index: 2
#2Enzo TartaglioneH-Index: 5
Last. Marco GrangettoH-Index: 23
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#1Antonella BarrecaH-Index: 13
#2Emanuel Bottasso (UNITO: University of Turin)
Last. Dario Roccatello (UNITO: University of Turin)H-Index: 54
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Amyloidosis comprises a spectrum of disorders characterized by the extracellular deposition of amorphous material, originating from an abnormal serum protein. The typing of amyloid into its many variants represents a pivotal step for a correct patient management. Several methods are currently used, including mass spectrometry, immunofluorescence, immunohistochemistry, and immunogold labeling. The aim of the present study was to investigate the accuracy and reliability of immunohistochemistry by ...
#1Alberto Ragni (UNITO: University of Turin)H-Index: 2
#2Alice Nervo (UNITO: University of Turin)H-Index: 8
Last. Silvia Uccella (University of Insubria)H-Index: 25
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Pituitary metastases (PM) are uncommon findings and are mainly derived from breast and lung cancers. No extensive review of PM from neuroendocrine neoplasms (NENs) is on record. Here we describe a clinical case of PM from pancreatic NEN and review the clinical features of PM from NENs reported in the literature. A case of PM from a pancreatic NEN followed at our institution is described. We also reviewed the 43 cases of PM from NENs reported in the literature. A 59-year old female patient, previ...
#1Luca Bertero (UNITO: University of Turin)H-Index: 14
#2Luisella Righi (UNITO: University of Turin)H-Index: 33
Last. Andreas von Deimling (DKFZ: German Cancer Research Center)H-Index: 130
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Abstract Diagnosis of malignant pleural mesothelioma (MPM) is a challenging task because of its potential overlap with other neoplasms or even with reactive conditions. Recently, DNA methylation analysis proved to be an effective tool for tumor diagnosis. In the present study, this approach was tested for MPM diagnosis. A discovery (n=33) and an independent validation cohort (n=46) of MPM samples were subjected to array-based DNA methylation analyses and their DNA methylation patterns were compa...
#1Luca Bertero (UNITO: University of Turin)H-Index: 14
#2Alessandro Gambella (UNITO: University of Turin)H-Index: 4
Last. Paola Cassoni (UNITO: University of Turin)H-Index: 56
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Aims null Novel prognostic markers are warranted for gastrointestinal stromal tumours. Caveolin-1 is a multifunctional protein that proved to be associated with outcome in multiple tumour types. Aim of this study was to investigate Caveolin-1 expression and prognostic efficacy in a series of gastrointestinal stromal tumours. null Methods null Caveolin-1 expression was assessed by immunohistochemistry in a retrospective series of 66 gastrointestinal stromal tumours representative of the different...
#4Andrea Bianconi (UNITO: University of Turin)H-Index: 1
This observational study evaluated SARS-CoV-2 IgG seroprevalence and related clinical, demographic, and occupational factors among workers at the largest tertiary care University-Hospital of Northwestern Italy and the University of Turin after the first pandemic wave of March–April 2020. Overall, about 10,000 individuals were tested; seropositive subjects were retested after 5 months to evaluate antibodies waning. Among 8769 hospital workers, seroprevalence was 7.6%, without significant differen...
#1Jasna Metovic (UNITO: University of Turin)H-Index: 7
#2Isabella Castellano (UNITO: University of Turin)H-Index: 27
Last. Mauro Papotti (UNITO: University of Turin)H-Index: 98
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According to the 2019 WHO classification of breast tumors, neuroendocrine neoplasms (NENs) are classified into well-differentiated NE tumors (NET) and poorly differentiated NE carcinomas (NEC), while other breast cancers (BCs) of special and no special type with neuroendocrine (NE) features are not incorporated in this scheme anymore. We aimed to assess whether INSM1, a novel NE marker, could have a role in breast NEN subtyping. We selected 63 BCs operated from 2003 to 2018, classified as BCs wi...
We investigated the role of the selective avoidance of haematopoietically active pelvic bone marrow (BM), with a targeted intensity-modulated radiotherapy (IMRT) approach, to reduce acute hematologic toxicity (HT) in anal cancer patients undergoing concurrent chemo-radiation. We designed a one-armed two-stage Simon’s design study to test the hypothesis that BM-sparing IMRT would improve by 20% the rate of G0–G2 (vs. G3–G4) HT, from 42% of RTOG 0529 historical data to 62% (α = 0.05; β = 0.20). A ...
#1Luca Bertero (UNITO: University of Turin)H-Index: 14
#2Fulvio Borella (UNITO: University of Turin)H-Index: 7
Last. Chiara Benedetto (UNITO: University of Turin)H-Index: 57
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Infection by SARS-CoV-2 has been shown to involve a wide range of organs and tissues, leading to a kaleidoscope of clinical conditions. Within this spectrum, an involvement of the fetal-maternal unit could be expected, but, so far, the histopathological evaluation of placentas delivered by women with SARS-CoV-2 infection did not show distinct hallmarks. A consecutive series of 11 placentas, delivered by 10 women with COVID-19 admitted to our Obstetrics and Gynecology clinic have been investigate...
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