James B. Seward
Mayo Clinic
Internal medicineRadiologySurgeryDoppler effectCardiologyHemodynamicsCardiac catheterizationMitral valveHeart failureVentricleAtrial fibrillationHeart diseaseRegurgitation (circulation)Doppler echocardiographyMitral regurgitationIn patientMyocardial infarctionDiastoleMedicineEjection fraction
Publications 580
#1Saeed A.L. Ahmari (Mayo Clinic)H-Index: 3
#2T. Jared Bunch (Mayo Clinic)H-Index: 58
Last. Krishnaswamy Chandrasekaran (Mayo Clinic)H-Index: 35
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Background Atrial rhythm disturbances, in particular atrial fibrillation (AF) and flutter (AFL), are common in the denervated transplanted heart. However, there is a relative paucity of data in the prevalence, mechanism of arrhythmia, and long-term significance. Objectives (1) Determine the prevalence of AF and AFL in heart transplant patients, (2) define the echo/Doppler features associated with arrhythmia, and (3) evaluate the impact of arrhythmia on long-term survival. Methods All patients wh...
91 CitationsSource
#1Roberto M. Lang (U of C: University of Chicago)H-Index: 110
#2Michelle Bierig (SLU: Saint Louis University)H-Index: 8
Last. William J. Stewart (Cleveland Clinic)H-Index: 74
view all 14 authors...
16.4k CitationsSource
#1Yoko Miyasaka (Mayo Clinic)H-Index: 12
#2Marion E. Barnes (Mayo Clinic)H-Index: 35
Last. Teresa S.M. Tsang (Mayo Clinic)H-Index: 56
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Background and Purpose— With the changes in management of atrial fibrillation (AF) over time, it is possible that the time trends of post-AF stroke incidence and mortality have changed. We sought to determine whether the incidence and survival of ischemic stroke after AF diagnosis have improved. Methods— We identified the Olmsted County, Minn, residents who developed first AF from 1980 to 2000 and followed them in medical records to 2004. The outcomes were first ischemic stroke and death. Result...
126 CitationsSource
#1Guilherme H. Oliveira (Mayo Clinic)H-Index: 21
#2James B. Seward (Mayo Clinic)H-Index: 137
Last. Ulrich Specks (Mayo Clinic)H-Index: 80
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OBJECTIVE To describe the spectrum and clinical implications of echocardiographic findings associated with Wegener granulomatosis. PATIENTS AND METHODS We retrospectively reviewed the clinical records and echocardiographic data of consecutive patients with confirmed Wegener granulomatosis referred to the echocardiography laboratory during the 21-year period from 1976 through 1997. RESULTS Of the 85 patients identified as having confirmed Wegener granulomatosis, 73 (86%) were found to have echoca...
89 CitationsSource
#1Christine H. Attenhofer Jost (Mayo Clinic)H-Index: 11
#2Heidi M. Connolly (Mayo Clinic)H-Index: 75
Last. A. Jamil Tajik (Mayo Clinic)H-Index: 141
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Background— Sinus venosus atrial septal defect (SVASD) differs from secundum atrial septal defect by its atrial septal location and its association with anomalous pulmonary venous connection (APVC). Data on long-term outcome after surgical repair are limited. Methods and Results— We reviewed outcomes of 115 patients (mean age±SD 34±23 years) with SVASD who had repair from 1972 through 1996. APVC was present in 112 patients (97%). Early mortality was 0.9%. Complete follow-up was obtained for 108 ...
134 CitationsSource
#1Yasuhiko Takemoto (OCU: Osaka City University)H-Index: 20
#2Marion E. BarnesH-Index: 35
Last. Teresa S.M. TsangH-Index: 56
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Left atrial (LA) volume is a barometer of diastolic dysfunction. Whether it predicts congestive heart failure (CHF) in patients with preserved left ventricular (LV) systolic function is not known. Olmsted County, Minnesota, residents aged ≥65 years referred for transthoracic echocardiography from 1990 to 1998, who were in sinus rhythm without a history of CHF were followed in the medical records to 2003 (mean follow-up duration 4.3 ± 2.7 years). Of the 1,495 patients identified, 1,375 (92%) with...
371 CitationsSource
#1Yasuhiko Takemoto (Mayo Clinic)H-Index: 20
#2Patricia A. Pellikka (Mayo Clinic)H-Index: 101
Last. Theodore P. Abraham (Mayo Clinic)H-Index: 66
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Background Strain echocardiography can depict segmental mechanical activity with high temporal and spatial accuracy, and may allow assessment of segmental relaxation not possible with conventional echocardiography. Methods Conventional and strain echocardiography were performed in healthy volunteers (young [group 1] and old [group 2]) and patients with normal 2-dimensional and stress echocardiography, with either normal global diastolic function (group 3a) or grade I or II global diastolic dysfu...
32 CitationsSource
#1Iftikhar J. Kullo (Mayo Clinic)H-Index: 58
#2James B. Seward (Mayo Clinic)H-Index: 137
Last. Stephen T. Turner (Mayo Clinic)H-Index: 72
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Background Emerging data suggest that C-reactive protein (CRP), a marker of inflammation, is associated with functional properties of arteries. We investigated the relationship of CRP to measures of arterial wave reflection and stiffness (aortic augmentation index [AIX], carotid-femoral pulse wave velocity [PWV], and pulse pressure) in asymptomatic individuals from the community. Methods Subjects ( n = 214) had a mean age of 59 years and 53% were men. CRP was measured by a high-sensitivity assay...
151 CitationsSource
#1William H. Hansen (Mayo Clinic)H-Index: 6
#2Thomas Behrenbeck (Mayo Clinic)H-Index: 26
Last. James B. Seward (Mayo Clinic)H-Index: 137
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A total of 59 patients (≥ 65 years of age) with normal left ventricular function (ejection fraction > 50%) and varying degrees of aortic valve structure and hemodynamics (normal to severely stenotic) were screened; 50 were subsequently enrolled. Continuous wave Doppler echocardiography in the descending thoracic aorta showed two general patterns: (1) in aortic stenosis, the pattern consisted of two peak systolic velocity components (S 1 and S 2 ); and (2) in normal aortic valve function, the pat...
7 CitationsSource
#1Bernard J. Gersh (Mayo Clinic)H-Index: 163
#2Teresa S.M. Tsang (Mayo Clinic)H-Index: 56
Last. James B. Seward (Mayo Clinic)H-Index: 137
view all 4 authors...
The growing ‘epidemic’ of atrial fibrillation (AF), with its associated morbidity and mortality, intersects with a number of risk factors including ageing and other conditions including thromboembolism, stroke, congestive heart failure, hypertension, and also perhaps metabolic syndrome and systemic inflammation. Currently in the USA, ∼2.3 million people are diagnosed with AF and, on the basis of the US census, this number is expected to rise to 3.3 million by 2020 and to 5.6 million by 2050. Thi...
23 CitationsSource