James B. Seward
Mayo Clinic
Internal medicineRadiologySurgeryDoppler effectCardiologyHemodynamicsCardiac catheterizationMitral valveHeart failureVentricleAtrial fibrillationHeart diseaseRegurgitation (circulation)Doppler echocardiographyMitral regurgitationIn patientMyocardial infarctionDiastoleMedicineEjection fraction
Publications 580
#1Hong MengH-Index: 2
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#1Rowlens M. Melduni (Mayo Clinic)H-Index: 11
#2Krishnaswamy Chandrasekaran (Mayo Clinic)H-Index: 35
Last. Naser M. Ammash (Mayo Clinic)H-Index: 35
view all 9 authors...
Background The relation of left atrial (LA) appendage peak emptying flow velocity (LAAEV) with energy requirement for successful direct-current cardioversion (DCCV) in persistent atrial fibrillation (AF) is unknown. LAAEV correlates with success of cardioversion of AF to sinus rhythm, both of which are related to the LA size and the chronicity of AF. We tested the hypothesis that LAAEV can predict optimal energy required for DCCV in persistent AF (>48 hours). Methods We studied 1050 consecutive ...
6 CitationsSource
#1Martin Osranek (Medical University of Vienna)H-Index: 8
#2James B. Seward (Mayo Clinic)H-Index: 137
Last. Manfred Zehetgruber (Medical University of Vienna)H-Index: 7
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Background The aim of this study was to test the hypothesis that diastolic dysfunction associated with increased filling pressures is unlikely in a structurally normal heart and to assess whether 2-dimensional echocardiography can facilitate diastolic function grading in a clinical setting. Methods Consecutive patients referred for transthoracic echocardiography received a comprehensive Doppler echocardiographic evaluation of diastolic function and measurements of left ventricular ejection fract...
21 CitationsSource
#1Partho P. Sengupta (Mayo Clinic)H-Index: 58
#2Vijay K. Krishnamoorthy (Mayo Clinic)H-Index: 6
Last. Marek Belohlavek (Mayo Clinic)H-Index: 42
view all 10 authors...
Doppler tissue imaging (DTI) and DTI-derived strain imaging are robust physiologic tools used for the noninvasive assessment of regional myocardial function. As a result of high temporal and spatial resolution, regional function can be assessed for each phase of the cardiac cycle and within the transmural layers of the myocardial wall. Newer techniques that measure myocardial motion by speckle tracking in gray-scale images have overcome the angle dependence of DTI strain, allowing for measuremen...
365 CitationsSource
#1Yoko Miyasaka (Kansai Medical University)H-Index: 12
#2Marion E. Barnes (Mayo Clinic)H-Index: 35
Last. Teresa S.M. Tsang (Mayo Clinic)H-Index: 56
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Aims To estimate the incidence of dementia after the first atrial fibrillation (AF), and its impact on survival in a community-based cohort. Methods and results Olmsted County, Minnesota adult residents diagnosed with first AF during 1986–2000 were identified, and followed until 2004. The primary outcome was new detection of dementia. Interim stroke was censored in the analyses. Of 2837 subjects (71 ± 15 years old) diagnosed with first AF and without any evidence of cognitive dysfunction or stro...
183 CitationsSource
#1Karen M. Modesto (Mayo Clinic)H-Index: 10
#2Angela Dispenzieri (Mayo Clinic)H-Index: 138
Last. Theodore P. Abraham (Mayo Clinic)H-Index: 66
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Aims Primary amyloidosis (AL) is a systemic disease; however, there is limited information regarding the presence and character of vascular abnormalities. Methods and results Validated ultrasound techniques were used to prospectively determine carotid artery intimal–medial thickness (IMT) and brachial artery flow-mediated dilatation (FMD) in 59 consecutive AL patients and 17 age-similar, healthy, asymptomatic volunteers (CON). Carotid IMT was increased in AL when compared with CON (0.07 ± 0.02 v...
27 CitationsSource
#1Yoko Miyasaka (Mayo Clinic)H-Index: 12
#2Marion E. Barnes (Mayo Clinic)H-Index: 35
Last. Teresa S.M. Tsang (Mayo Clinic)H-Index: 56
view all 8 authors...
Abstract Purpose We aimed to determine the long-term, gender-specific incidence and mortality risk of coronary ischemic events after first atrial fibrillation (AF). Methods In this longitudinal cohort study, adult residents of Olmsted County, Minnesota, with an electrocardiogram-confirmed AF first documented in 1980 to 2000 and without prior coronary heart disease, were followed to 2004. The primary outcome was first coronary events (angina with angiographic confirmation, unstable angina, nonfat...
83 CitationsSource
#1Yoko Miyasaka (Mayo Clinic)H-Index: 12
#2Marion E. Barnes (Mayo Clinic)H-Index: 35
Last. Teresa S.M. Tsang (Mayo Clinic)H-Index: 56
view all 7 authors...
Objectives The purpose of this study was to assess the mortality trends of atrial fibrillation (AF) in a community. Background Limited data exist regarding the mortality trends of patients diagnosed with first AF. Methods A community-based cohort of adult residents of Olmsted County, Minnesota, who had electrocardiogram-confirmed first-documented AF in the years 1980 to 2000 were identified and followed to 2004 or death. The primary outcome was all-cause mortality. Results Of a total of 4,618 re...
472 CitationsSource
#1Walter P. Abhayaratna (Mayo Clinic)H-Index: 15
#2Kaniz Fatema (Mayo Clinic)H-Index: 11
Last. Teresa S Tsang (Mayo Clinic)H-Index: 4
view all 6 authors...
#1Martin Osranek (Mayo Clinic)H-Index: 8
#2Francesca Bursi (Mayo Clinic)H-Index: 24
Last. James B. Seward (Mayo Clinic)H-Index: 137
view all 3 authors...
A 25-year-old physical fitness trainee was referred to receive an echocardiogram after being told that her ECG was mildly abnormal. She had experienced no symptoms apart from occasional deep, sighing breathing and rare vasovagal spells during adolescence. On physical examination, her second heart sound was somewhat more widely split with inspiration, and a grade 1/6 systolic ejection murmur was heard at the pulmonic region. The echocardiogram showed a huge fenestrated atrial septal aneurysm with...
2 CitationsSource