James B. Seward
Mayo Clinic
Internal medicineRadiologySurgeryDoppler effectCardiologyHemodynamicsCardiac catheterizationMitral valveHeart failureVentricleAtrial fibrillationHeart diseaseRegurgitation (circulation)Doppler echocardiographyMitral regurgitationIn patientMyocardial infarctionDiastoleMedicineEjection fraction
569Publications
137H-index
52.9kCitations
Publications 580
Newest
#1Nathaniel W. Taggart (Mayo Clinic)H-Index: 14
#2Frank Cetta (Mayo Clinic)H-Index: 46
Last. Benjamin W. Eidem (Mayo Clinic)H-Index: 28
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In adults, the left atrial (LA) volume has been shown to reflect diastolic function and is a powerful predictor of cardiac morbidity and mortality. Normative LA volume values in children and the effect of loading conditions on the LA volume in those with congenital heart disease are lacking. The purposes of the present study were to (1) establish normal LA volume values for children, (2) assess the effect of left ventricular volume loading conditions on LA volume, and (3) describe the effect of ...
26 CitationsSource
Infiltrative cardiomyopathies are characterized by the deposition of abnormal substances that cause the ventricular walls to become progressively rigid, thereby impeding ventricular filling. Some infiltrative cardiac diseases increase ventricular wall thickness, while others cause chamber enlargement with secondary wall thinning. Increased wall thickness, small ventricular volume, and occasional dynamic left ventricular outflow obstruction (e.g., amyloidosis) can outwardly appear similar to cond...
158 CitationsSource
#1Grace Casaclang-Verzosa (Mayo Clinic)H-Index: 17
#2Marion E. Barnes (Mayo Clinic)H-Index: 35
Last. Teresa S.M. Tsang (Mayo Clinic)H-Index: 56
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Background: The data regarding the interrelationships of high-sensitive C-reactive protein (CRP), left atrial (LA) volume, and atrial fibrillation (AF) are sparse. Additionally, while LA volume has been shown to be useful for prediction of AF in low-to-moderate risk populations, its predictive value in clinically high-risk populations is unknown. Methods: SAFHIRE (Study of Atrial Fibrillation in High Risk Elderly) is an ongoing prospective study of the pathophysiology of first AF in persons aged...
20 CitationsSource
#1Gustavo G BlumeH-Index: 3
#2Marion E. BarnesH-Index: 35
Last. Teresa S.M. TsangH-Index: 56
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#1Rowlens M. MelduniH-Index: 11
#2Rakesh M. SuriH-Index: 63
Last. Bernard J. GershH-Index: 163
view all 7 authors...
Introduction Atrial fibrillation (AF) is a common complication after cardiac surgery. It is known that abnormal ventriculovascular coupling is a mechanism underlying heart failure. Therefore, we hy...
#1Rowlens M. MelduniH-Index: 11
#2Bernard J. GershH-Index: 163
Last. James B. SewardH-Index: 137
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#1Rowlens M. MelduniH-Index: 11
#2Rakesh M. SuriH-Index: 63
Last. Bernard J. GershH-Index: 163
view all 7 authors...
1 Citations
#1Gustavo G BlumeH-Index: 3
#2Marion E. BarnesH-Index: 35
Last. Teresa S.M. TsangH-Index: 56
view all 9 authors...
#1Gustavo G Blume (Mayo Clinic)H-Index: 3
#2Marion E. Barnes (Mayo Clinic)H-Index: 35
Last. Teresa S.M. Tsang (Mayo Clinic)H-Index: 56
view all 9 authors...
Introduction: Atrial fibrillation (AF) is associated with a significant increase in stroke risk. Left atrial (LAV) is a powerful predictor of AF, and of stroke even in the absence of AF. Yet, the mechanism underlying the relationship of atrial volume and stroke remains poorly understood. Methods: Prospectively, outpatients visiting the medical clinics at the Mayo were invited to participate in this study of subclinical risk factors for AF, if they were of age ≥65 years, and had no history or evi...
#1Kaniz Fatema (Mayo Clinic)H-Index: 11
#2James B. Seward (Mayo Clinic)H-Index: 137
Last. Samuel J. Asirvatham (Mayo Clinic)H-Index: 57
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Atrial fibrillation (AF) is a multivariable disease. Young patients with paroxysmal AF without structural cardiac abnormality (“lone AF”) likely have a primary electropathy with excellent results from radiofrequency ablation. However, with persistent AF with cardiac abnormalities, including left atrial enlargement and systolic ventricular dysfunction (ejection fraction percent), the electropathy is considered secondary and ablation results poor. We describe a case with persistent AF, depressed s...
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