James B. Seward
Mayo Clinic
Internal medicineRadiologySurgeryDoppler effectCardiologyHemodynamicsCardiac catheterizationMitral valveHeart failureVentricleAtrial fibrillationHeart diseaseRegurgitation (circulation)Doppler echocardiographyMitral regurgitationIn patientMyocardial infarctionDiastoleMedicineEjection fraction
569Publications
137H-index
52.9kCitations
Publications 577
Newest
#1Christine H. Attenhofer Jost (Mayo Clinic)H-Index: 11
#2Heidi M. Connolly (Mayo Clinic)H-Index: 75
Last. James B. Seward (Mayo Clinic)H-Index: 137
view all 6 authors...
OBJECTIVE To identify the incidence of left heart abnormalities in patients with Ebstein anomaly, recognizing that left-sided lesions in this patient group have been overlooked. PATIENTS AND METHODS According to the echocardiography database at the Mayo Clinic in Rochester, Minn, 106 consecutive patients with Ebstein anomaly underwent echocardiography between July 1, 2001, and February 28, 2003. Clinical data as well as electrocardiographic and echocardiographic reports and images were reviewed....
124 CitationsSource
#1Yoram Agmon (Mayo Clinic)H-Index: 44
#2Irene Meissner (Mayo Clinic)H-Index: 37
Last. Bijoy K. Khandheria (Mayo Clinic)H-Index: 71
view all 9 authors...
Background The determinants of interatrial septal (IAS) thickening ("lipomatous hypertrophy"), a common echocardiographic finding in the elderly, are poorly defined. The objective of this study was to determine the clinical, laboratory, and transesophageal echocardiographic correlates of IAS thickening in the general population. Methods The thickness of the IAS was measured by transesophageal echocardiography in 384 patients (median age: 66 years; range: 51-101 years; 53% men) participating in a...
13 CitationsSource
#1Jong-Won Ha (Mayo Clinic)H-Index: 53
#2Jae K. Oh (Mayo Clinic)H-Index: 119
Last. A. Jamil Tajik (Mayo Clinic)H-Index: 141
view all 8 authors...
Left ventricular filling pressures can be estimated reliably by combining mitral inflow early diastolic velocity (E) and annulus velocity (E′). An increased E/E′ ratio reflects elevated filling pressures and may be useful in assessing an abnormal increase in filling pressures for patients with diastolic dysfunction. The purpose of this study was to evaluate the feasibility of supine bicycle exercise Doppler echocardiography for assessing left ventricular diastolic pressure during exercise. Mitra...
221 CitationsSource
#1Roberto M. LangH-Index: 110
#2Michelle BierigH-Index: 8
Last. Marielle Scherrer-CrosbieH-Index: 56
view all 21 authors...
La quantification de la dimension des Cavites Cardiaques, de la masse ventriculaire, et de la fonction systolique des ventricules est un element essentiel de l’evaluation clinique par echocardiographie et une deses indications les plus frequentes. La standardisation de la quantification des Cavites Cardiaques a ete une des premieres preoccupations des echocardiographistes, et les recommendations concernant cette quantification figurent parmi les articles les plus cites dans la litterature. Cette...
#1Karen M. Modesto (Mayo Clinic)H-Index: 10
#2Angela Dispenzieri (Mayo Clinic)H-Index: 138
Last. Theodore P. Abraham (Johns Hopkins University)H-Index: 66
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Aims To assess left atrial (LA) function and determine the prevalence of LA dysfunction in AL amyloidosis (AL) using conventional and strain echocardiography. Methods and results LA ejection fraction, LA filling fraction, LA ejection force, peak LA systolic strain rate (LAsSR), and LA systolic strain (LA e) were determined in 95 AL patients (70 with and 25 without echocardiographic evidence of cardiac involvement, abbreviated CAL and NCAL, respectively), 30 age-matched controls (CON), and 20 pat...
78 CitationsSource
#1Josef Korinek (Mayo Clinic)H-Index: 23
#2Peter C. Anagnostopoulos (Mayo Clinic)H-Index: 4
Last. Marek Belohlavek (Mayo Clinic)H-Index: 42
view all 7 authors...
Background Ischemia is primarily a metabolic event. However, regional functional changes can be affected by structural alterations. We developed an experimental model of sole myocardial energy metabolism inhibition and characterized the resulting regional dysfunction. Methods In 12 pigs, we regionally inhibited creatine kinase (CK) and, consequently, myocyte high-energy phosphate transfer by intracoronary administration of iodoacetamide. Myocardial biopsies for CK activity and structural analyse...
14 CitationsSource
#1William H. Hansen (Mayo Clinic)H-Index: 6
#2Gregory Gilman (Mayo Clinic)H-Index: 7
Last. Bijoy K. Khandheria (Mayo Clinic)H-Index: 71
view all 9 authors...
Our echocardiography laboratory has completed the transition from an analog to a digital imaging laboratory. The process involved a thorough analysis of the practice and design of a complete digital solution. After an effective implementation of a robust reporting solution, the transition to digital imaging ensued. The implementation plan for digital imaging enabled the transition to be made without adversely affecting the practice, which has an average daily examination load of more than 200 pa...
6 CitationsSource
#1Gabriel Wk Yip (Mayo Clinic)H-Index: 6
#2Bijoy K. Khandheria (Mayo Clinic)H-Index: 71
Last. Theodore P. Abraham (Mayo Clinic)H-Index: 66
view all 9 authors...
Objectives This study was designed to determine whether strain echocardiography parameters reflect changes in regional myocardial perfusion during dobutamine stress. Background Strain echocardiography depicts regional myocardial mechanical activity. Ischemia has been shown to reduce systolic strain rate (sSR) and prolong the time to regional lengthening (T RL ). In an experimental model, we tested whether sSR and T RL tracked dobutamine-induced changes in regional myocardial perfusion (regional ...
35 CitationsSource
#1Kwan K. Law (Mayo Clinic)H-Index: 1
#2Josepha Binder (Mayo Clinic)H-Index: 8
Last. James B. Seward (Mayo Clinic)H-Index: 137
view all 6 authors...
Abstract We report a case of restrictive cardiomyopathy in which a distinct endothelial thickening of the atrial wall and pulmonary vein orifices was noted on transesophageal echocardiography. Echocardiographically guided endomyocardial biopsy of the thickening revealed an inflammatory infiltrate that was rich in giant cells and provided important clues about an underlying immune mechanism for the pathogenesis. Positive results from the antineutrophil cytoplasmic autoantibody assay supported the...
6 CitationsSource
#1Yoram Agmon (Mayo Clinic)H-Index: 44
#2Bijoy K. Khandheria (Mayo Clinic)H-Index: 71
Last. A. Jamil Tajik (Mayo Clinic)H-Index: 141
view all 11 authors...
Background An association between systemic inflammatory markers and the presence and severity of atherosclerotic plaques has not been demonstrated in a nonselected population. The purpose of this study was to examine the association of inflammatory markers with aortic atherosclerotic plaques in a sample of the general population and in a subgroup free of clinical vascular disease. Methods Transesophageal echocardiography was performed in 386 subjects (median age, 66 years; 53% men). We examined ...
23 CitationsSource