Conor Woods
Tallaght Hospital
Internal medicineEndocrinologySurgeryGene expressionNatural history11ß-hydroxysteroid dehydrogenase type 1Retrospective cohort studyAdipose tissuePhysical therapyPediatricsMineralocorticoid receptorMorningAdverse effectCohort studyYoung adultCraniopharyngiomaType 2 diabetesCirrhosisAdrenal insufficiencyHydrocortisoneFatty liverProlactinomaDiseasePituitary adenomaContext (language use)Body mass indexCortisoneLeptinGlucocorticoidType 2 Diabetes Mellitus5 Alpha-Reductase InhibitorHypothalamo pituitary adrenal axisCo administrationRadiation therapyObesityWeight lossDiabetes mellitusCortisol awakening responseMedicineCohortArea under the curveUrinary systemComplicationBiologyImmune systemGastroenterologyPharmacology
38Publications
13H-index
792Citations
Publications 37
Newest
#1Adam H. DyerH-Index: 11
Last. Sean Kennelly (Trinity College, Dublin)H-Index: 20
view all 13 authors...
Midlife Type 2 Diabetes Mellitus (T2DM) is associated with a greater risk of dementia in later life. Peripheral inflammation and its impact on cognition is proposed as one of the pathological mechanisms mediating this link. However, studies have primarily focused on older individuals with established cognitive impairment and a long duration of T2DM. Importantly, knowledge of which individuals with midlife T2DM who are at greatest risk of later cognitive decline is lacking. We examined the cross-...
1 CitationsSource
#1Nantia Othonos (University of Oxford)H-Index: 1
#2Thomas Marjot (John Radcliffe Hospital)H-Index: 14
Last. Jeremy W. Tomlinson (University of Oxford)H-Index: 61
view all 15 authors...
CONTEXT Glucocorticoids (GC) are commonly prescribed, but their use is associated with adverse metabolic effects. 5a-reductase inhibitors (5aRI) are also frequently prescribed, mainly to inhibit testosterone conversion to dihydrotestosterone. However, they also prevent the inactivation of GCs. OBJECTIVE We hypothesised that 5aRIs may worsen the adverse effects of GCs. DESIGN Prospective, randomised study. PATIENTS 19 healthy male volunteers (age; 45±2 years, BMI; 27.1±0.7kg/m2). INTERVENTIONS Pa...
2 CitationsSource
#1Roxana Maria Tudor (Beaumont Hospital)H-Index: 2
#2Aoife Garrahy (Beaumont Hospital)H-Index: 7
Last. Christopher J. Thompson (Beaumont Hospital)H-Index: 30
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Background Thyroid dysfunction (TD) occurs in 13.4% of diabetic patients, which has prompted recommendations for annual thyroid screening in patients with diabetes. However, recommendations for annual screening should be based on disease incidence rather than prevalence.
1 CitationsSource
#1Rachel K Crowley (UCD: University College Dublin)H-Index: 17
#2Conor Woods (Tallaght Hospital)H-Index: 13
Last. Jeremy W. Tomlinson (University of Oxford)H-Index: 61
view all 12 authors...
OBJECTIVE AND CONTEXT: Increasing adiposity, ageing and tissue-specific regeneration of cortisol through the activity of 11β-hydroxysteroid dehydrogenase type 1 have been associated with deterioration in glucose tolerance. We undertook a longitudinal, prospective clinical study to determine if alterations in local glucocorticoid metabolism track with changes in glucose tolerance. DESIGN, PATIENTS, AND MEASUREMENTS: Sixty-five overweight/obese individuals (mean age 50.3 ± 7.3 years) underwent ora...
5 CitationsSource
#1Rachel K CrowleyH-Index: 17
#2Conor WoodsH-Index: 13
Last. Jeremy W. Tomlinson (University of Oxford)H-Index: 61
view all 3 authors...
Source
#1Khalid S. Ahmed (Boston Children's Hospital)H-Index: 2
#2Delia Bogdanet (Boston Children's Hospital)H-Index: 6
Last. James Gibney (Boston Children's Hospital)H-Index: 30
view all 9 authors...
INTRODUCTION: The aldosterone/renin ratio is the initial screening test for primary hyperaldosteronism (PHA), but little data exists regarding ethnic variations in this. METHODS: Following clinical observation of a high prevalence of abnormal aldosterone/renin ratio (ARR) in patients of African-origin, we retrospectively reviewed all ARR measurements in a single centre over 10 years. Rates of hypokalaemia, intraventricular septal thickness (IVS, by echocardiography) and adrenal imaging were reco...
4 CitationsSource
#1Riccardo Pofi (NIHR: National Institute for Health Research)H-Index: 16
#2Chona Feliciano (Queen Elizabeth Hospital Birmingham)H-Index: 1
Last. Jeremy W. Tomlinson (NIHR: National Institute for Health Research)H-Index: 61
view all 11 authors...
Context: The 250-μg short Synacthen (corticotropin) test (SST) is the most commonly used tool to assess hypothalamo-pituitary-adrenal (HPA) axis function. There are many potentially reversible causes of adrenal insufficiency (AI), but no data to guide clinicians as to the frequency of repeat testing or likelihood of HPA axis recovery. Objective: To use the SST results to predict adrenal recovery. Design: A retrospective analysis of 1912 SSTs data. Patients: Seven hundred seventy-six patients wit...
23 CitationsSource
#1Riccardo PofiH-Index: 16
#2Chona FelicianoH-Index: 1
Last. Jeremy TomlinsonH-Index: 2
view all 11 authors...
Source
#1Thomas MarjotH-Index: 14
#2Nantia OthonosH-Index: 1
Last. Jeremy TomlinsonH-Index: 2
view all 7 authors...
Source
#1Thomas MarjotH-Index: 14
#2Nantia OthonosH-Index: 1
Last. Jeremy TomlinsonH-Index: 2
view all 7 authors...
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