Antonia M. Joussen
Charité
OphthalmologyInternal medicineEndocrinologySurgeryPathologyChemistryMacular degenerationChoroidRetinaMelanomaVisual acuityNeovascularizationGlaucomaDiabetic retinopathyRetinalChoroidal neovascularizationIn patientCancer researchMedicineBiologyCell biology
368Publications
39H-index
4,483Citations
Publications 372
Newest
#1Antonia M. Joussen (Charité)H-Index: 39
The World Health Organization designated the outbreak of the novel coronavirus, COVID-19, as a pandemic on March 11, 2020, after its rapid spread to countries throughout the world.1 There is a strong need to support the ophthalmic community to help guide decision- making during these unprecedented times, where infection control is of utmost concern and disruption to regular clinical practice is highly likely. This is particularly important for patients with retinal diseases who are receiving int...
1 CitationsSource
#1Rudolf F. Guthoff (University of Rostock)H-Index: 39
#2Antonia M. Joussen (Charité)H-Index: 39
Last. Norbert Bornfeld (University of Duisburg-Essen)H-Index: 51
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#1Johannes Gollrad (Charité)H-Index: 3
#2Christopher Rabsahl (Charité)
Last. Dirk Boehmer (Charité)H-Index: 20
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BACKGROUND Proton beam therapy is a well-established treatment option for patients with uveal melanoma (UM). The treatment procedure, in general, includes placing radiopaque clips to ensure exact eye-positioning during radiotherapy, followed by the delivery of proton irradiation. The short-term burden associated with proton therapy in patients with UM has rarely been addressed. In this prospective study, we investigated the physiological and psychological aspects of proton therapy that might aff...
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#1Aline I. Riechardt (Charité)H-Index: 12
#2Emine Kilic (EUR: Erasmus University Rotterdam)H-Index: 20
Last. Antonia M. Joussen (Charité)H-Index: 39
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Over the last ten years, much has been learnt about the genetic characteristics and genetic evolution of uveal melanoma. It has been shown that uveal melanoma differs fundamentally from non-uveal melanoma and is an independent genetic subtype. Compared to other tumours, uveal melanoma has a low mutational burden. There are recurring chromosomal aberrations with losses of 1p, 6q, 8p and 16q, gains of 6p and 8q, and the presence of monosomy 3. GNAQ, GNA11, PLCB4, CYSLTR2, MAPKAPK5, as well as muta...
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BACKGROUND Uveal melanoma is a rare intraocular tumour, for which there is currently no national evidence-based guideline in Germany. The aim of this project was to provide a common standard operating procedure (SOP) for the diagnosis, treatment and follow-up care of uveal melanoma, within the network of German leading oncology centres funded by German Cancer Aid. The SOP was created as part of a moderated consensus process. RESULTS AND CONCLUSION In a multistage process, a common SOP was develo...
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#1Kwan Wun Tsang (HKU: University of Hong Kong)
#2Antonia M. Joussen (Charité)H-Index: 39
Last. Amy C. Y. Lo (HKU: University of Hong Kong)H-Index: 35
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The term “pachychoroid” refers to a newly described phenotype in which functional and structural choroidal changes are thought to play a key pathogenic role in a spectrum of related retinal disorders. A more detailed understanding of how the choroid is involved within this spectrum and a better knowledge of the most relevant clinical signs of the pachychoroid phenotype are important to differentiate these disorders from other retinal conditions. Our objectives are to provide a literature review ...
4 CitationsSource
#1Daniel Pilger (Charité)H-Index: 15
#2Anna-Karina B. Maier (Charité)H-Index: 17
Last. Necip Torun (Charité)H-Index: 17
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Introduction:In instances where peribulbar anaesthesia (PBA) cannot be used, Descemet membrane endothelial keratoplasty (DMEK) surgery can be performed under topical anaesthesia (TA). We evaluated ...
1 CitationsSource
#1Sergio Crespo-Garcia (Charité)H-Index: 8
#2Nadine Reichhart (Charité)H-Index: 13
Last. Antonia M. Joussen (Charité)H-Index: 39
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Diabetic retinopathy is characterized by dysfunction of the retinal vascular network, combined with a persistent low-grade inflammation that leads to vision-threatening complications. Netrin-4 (NTN4) is a laminin-related secreted protein and guidance cue molecule present in the vascular basal membrane and highly expressed in the retina. A number of studies inferred that the angiogenic abilities of NTN4 could contribute to stabilize vascular networks and modulate inflammation. Analyzing human spe...
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