Manuel Patino
Harvard University
Imaging phantomInternal medicineRadiologyBiomedical engineeringIterative reconstructionMagnetic resonance imagingDigital Enhanced Cordless TelecommunicationsNoise reductionTomographyRetrospective cohort studyAttenuationHounsfield scaleMedical physicsContrast (vision)PancreasPancreatic ductPancreatic cancerAngiographyStone compositionMaterial densityRadiation doseNuclear medicineLesion detectionDual energy ctCt imagingMonochromatic colorIodineImage qualityReceiver operating characteristicMedicineCohort
Publications 24
#1Marta Sandini (Harvard University)H-Index: 15
#2Adrian A. Negreros-Osuna (Harvard University)H-Index: 2
Last. Carlos Fernandez-del Castillo (Harvard University)H-Index: 101
view all 10 authors...
Background Pancreatic cancer induces parenchymal atrophy and duct dilation. The aim of this study was to evaluate whether these radiologic modifications are associated with outcomes.
3 CitationsSource
#1M. SandiniH-Index: 1
Last. C. Fernandez-del CastilloH-Index: 17
view all 7 authors...
#1Azadeh Tabari (Harvard University)H-Index: 8
#2Manuel Patino (Harvard University)H-Index: 11
Last. Michael S. Gee (Harvard University)H-Index: 29
view all 8 authors...
AIM To evaluate dual-source high-pitch computed tomography (HPCT) imaging of the chest and abdomen as a rapid scanning technique to obtain diagnostic-quality imaging evaluation of infants and young children without sedation. MATERIALS AND METHODS Fifty-three paediatric patients (age 24.1±2 months) who underwent chest or abdomen HPCT (≥1.5) and standard pitch CT (SPCT, RESULTS Most of the CT examinations were performed in children who were >1 year old (n=15 and n=20) followed by ≤1 year old (n=8 ...
#1Manos Gkikas (MIT: Massachusetts Institute of Technology)H-Index: 8
#2Thomas Peponis (Harvard University)H-Index: 8
Last. Bradley D. Olsen (MIT: Massachusetts Institute of Technology)H-Index: 34
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Internal bleeding is an injury that can be difficult to localize and effectively treat without invasive surgeries. Injectable polymeric nanoparticles have been developed that can reduce clotting times and blood loss, but they have yet to incorporate sufficient diagnostic capabilities to assist in identifying bleeding sources. Herein, polymeric nanoparticles were developed to simultaneously treat internal bleeding while incorporating tracers for visualization of the nanoparticles by standard clin...
6 CitationsSource
#1Manuel Patino (Harvard University)H-Index: 11
#2Anushri Parakh (Harvard University)H-Index: 11
Last. Dushyant V. Sahani (Harvard University)H-Index: 94
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OBJECTIVE. The purpose of this study was to assess the feasibility of performing abdominopelvic aortoiliac CT angiography (CTA) with 16.0 g of iodine contrast medium acquired with low-energy (40 an...
12 CitationsSource
#1Marta Sandini (University of Milano-Bicocca)H-Index: 15
#2Manuel Patino (Harvard University)H-Index: 11
Last. Carlos Fernandez-del Castillo (Harvard University)H-Index: 101
view all 23 authors...
Importance Sarcopenia and sarcopenic obesity have been associated with poor outcomes in unresectable pancreatic cancer (PC). Neoadjuvant treatment (NT) is used increasingly to improve resectability; however, its effects on fat and muscle body composition have not been characterized. Objectives To evaluate whether NT affects muscle mass and adipose tissue in patients with borderline resectable PC (BRPC) and locally advanced PC (LAPC) and determine whether there were potential differences between ...
48 CitationsSource
#1Daniela Pfeiffer (TUM: Technische Universität München)H-Index: 13
#2Anushri Parakh (Harvard University)H-Index: 11
Last. Dushyant V. Sahani (Harvard University)H-Index: 94
view all 6 authors...
Purpose To determine the diagnostic potential of Material Density (MD) iodine images in dual-energy CT (DECT) for visualization and quantification of arterial phase hyperenhancement and washout in hepatocellular carcinomas compared to magnetic resonance imaging (MRI).
13 CitationsSource
#1Renata R. Almeida (Harvard University)H-Index: 6
#2Grace C. Lo (Harvard University)H-Index: 8
Last. Dushyant V. Sahani (Harvard University)H-Index: 94
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OBJECTIVE. The purpose of this article is to discuss the advances in CT acquisition and image postprocessing as they apply to imaging the pancreas and to conceptualize the role of radiogenomics and machine learning in pancreatic imaging. CONCLUSION. CT is the preferred imaging modality for assessment of pancreatic diseases. Recent advances in CT (dual-energy CT, CT perfusion, CT volumetry, and radiogenomics) and emerging computational algorithms (machine learning) have the potential to further i...
25 CitationsSource
#1Thorsten Sellerer (TUM: Technische Universität München)H-Index: 8
#2Peter B. Noël (TUM: Technische Universität München)H-Index: 30
Last. Dushyant V. Sahani (Harvard University)H-Index: 94
view all 14 authors...
Objectives Evaluation of imaging performance across dual-energy CT (DECT) platforms, including dual-layer CT (DLCT), rapid-kVp-switching CT (KVSCT) and dual-source CT (DSCT).
55 CitationsSource
#1Anushri Parakh (Harvard University)H-Index: 11
#2Manuel Patino (Harvard University)H-Index: 11
Last. Dushyant V. Sahani (Harvard University)H-Index: 94
view all 5 authors...
Purpose The purpose of this study is to evaluate the performance of material-specific iodine (MS-I) images generated by rapid kV-switching single-source dual-energy computed tomography (rsDECT) for distinguishing post-operative changes from local tumor recurrence in patients on follow-up for pancreatic adenocarcinoma after surgical resection.
7 CitationsSource