Haruhito Sugiyama
Nagasaki University
Internal medicineRadiologySurgeryPathologyOncologyImmunologyAsthmaLung cancerBronchial thermoplastyPrednisoloneExacerbationEosinophilRheumatoid arthritisLungBronchoscopyPleural effusionAnesthesiaMedicineEosinophil cationic proteinGastroenterology
Publications 173
The rapid global spread of the COVID-19 pandemic has posed a significant challenge to various countries in terms of the capacity of hospitals to admit and care for patients during the crisis. To estimate hospital capacity during the COVID-19 pandemic, clinicians working in tertiary hospitals around the world were surveyed regarding available COVID-19 hospital statistics. Data were obtained from 8 tertiary centers in 8 countries including the United States, United Kingdom, Switzerland, Turkey, Si...
#1Kazuma Yagi (Keio: Keio University)H-Index: 10
#2Akihiro ItoH-Index: 23
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RATIONALE The clinical features and prognosis of nontuberculous mycobacterial (NTM) pleuritis and pleural effusion combined with NTM lung disease (NTM-LD) remain unclear. OBJECTIVES To investigate the clinical features and prognosis of NTM pleuritis. METHODS This retrospective observational study included patients with NTM pleuritis from January 2001 to June 2018 across eight hospitals in Japan. NTM pleuritis was defined by a positive culture of NTM from pleural effusion. We matched patients wit...
#1Takashi KatsunoH-Index: 1
#2Manabu SuzukiH-Index: 4
Last. Haruhito SugiyamaH-Index: 19
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#1Yoshie TsujimotoH-Index: 2
#2Junko TeradaH-Index: 1
Last. Haruhito SugiyamaH-Index: 19
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BACKGROUND: The current gold standard in coronavirus disease (COVID-19) diagnostics is the real-time reverse transcription-polymerase chain reaction (RT-PCR) assay for detecting severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA in nasopharyngeal swab (NPS) samples. Alternatively, nasal swab (NS) or saliva swab (SS) specimens are used, although available data on test accuracy are limited. We examined the diagnostic accuracy of NPS/NS/SS samples for this purpose. METHODS: Ten patien...
#2Manabu SuzukiH-Index: 4
Last. Haruhito SugiyamaH-Index: 19
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A 62-year-old woman with rheumatoid arthritis and a history of receiving immunosuppressant therapy had a recurrence of lung adenocarcinoma with EGFR L858R mutation. Following 14 months of treatment with erlotinib, computed tomography (CT) findings revealed the presence of small diffuse nodules. Bronchoscopy was performed as metastasis was suspected; however, this was not detected on lung biopsy with forceps. Transbronchial lung cryobiopsy (TBLC) succeeded in detecting metastatic adenocarcinoma, ...
#1Kenji MaedaH-Index: 22
Last. Hiroaki Mitsuya (Kumamoto University)H-Index: 74
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While there are various attempts to administer COVID-19-convalescent plasmas to SARS-CoV-2-infected patients, neither appropriate approach nor clinical utility has been established. We examined the presence and temporal changes of the neutralizing activity of IgG fractions from 43 COVID-19-convalescent plasmas using cell-based assays with multiple endpoints. IgG fractions from 27 cases (62.8%) had significant neutralizing activity and moderately to potently inhibited SARS-CoV-2 infection in cell...
1 CitationsSource
#1Akihito TanakaH-Index: 1
#2Shohei YamamotoH-Index: 2
Last. Norio OhmagariH-Index: 21
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5 CitationsSource
#1Masaya SugiyamaH-Index: 33
#2Noriko KinoshitaH-Index: 6
Last. Masashi MizokamiH-Index: 81
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COVID-19, a novel coronavirus-related illness, has spread worldwide. Patients with apparently mild/moderate symptoms can suddenly develop severe pneumonia. Therefore, almost all COVID-19 patients require hospitalization, which can reduce limited medical resources in addition to overwhelming medical facilities. To identify predictive markers for the development of severe pneumonia, a comprehensive analysis of serum chemokines and cytokines was conducted using serial serum samples from COVID-19 pa...
8 CitationsSource