Kees van Grootheest
University of Groningen
PharmacyInternal medicineOdds ratioIntensive care medicinePediatricsProspective cohort studyEmergency medicineAdverse effectAlternative medicinePharmacoepidemiologyMEDLINEDrugAdverse drug reactionDrug reactionPatient reportingFamily medicineMedical emergencyPharmacovigilanceMedicinePharmacology
51Publications
22H-index
1,412Citations
Publications 51
Newest
#1Leàn RolfesH-Index: 7
#2Florence van HunselH-Index: 15
Last. Eugène van Puijenbroek (UG: University of Groningen)H-Index: 25
view all 4 authors...
Objective: Due to the rising number of patient reports in pharmacovigilance, the manner in which feedback is provided to patients is an element to be considered. The objective is to explore the satisfaction of patients towards personalized and general feedback in response to their reported adverse drug reactions (ADRs).Methods: Patients who reported an ADR to the Dutch Pharmacovigilance Centre for the first time in the period between October 2012 and April 2013 were included. Reporters received ...
Source
#1Leàn Rolfes (UG: University of Groningen)H-Index: 7
#2Florence van Hunsel (UG: University of Groningen)H-Index: 15
Last. Eugène van Puijenbroek (UG: University of Groningen)H-Index: 25
view all 5 authors...
PURPOSE: This study aims to explore the differences in reported information between adverse drug reaction (ADR) reports of patient and healthcare professionals (HCPs), and, in addition, to explore possible correlation between the reported elements of information. METHODS: This retrospective study compared the reported information between 200 ADR reports of patients and HCPs. Reports were rendered anonymous and scored for the presence or absence of predefined elements of information. These elemen...
Source
#1Loes de VriesH-Index: 3
#2Florence van Hunsel (UG: University of Groningen)H-Index: 15
Last. Kees van Grootheest (UG: University of Groningen)H-Index: 22
view all 5 authors...
BACKGROUND: During influenza pandemics, pregnant women have an increased risk of severe complications. Vaccination can diminish these complications. In the Netherlands, the adjuvanted vaccines Focetria® and Pandemrix® were used during the A/H1N1 (2009) influenza pandemic. The national vaccination scheme included pregnant women, but knowledge concerning the safety of adjuvants during pregnancy was lacking. The aim of the study is to assess safety of adjuvanted influenza vaccines during pregnancy....
Source
#1Leàn RolfesH-Index: 7
#2Judith Kolfschoten (UU: Utrecht University)H-Index: 2
Last. Kees van GrootheestH-Index: 22
view all 5 authors...
Background: To determine which actions are advisable for signals arising from a spontaneous reporting system, the Netherlands Pharmacovigilance Centre Lareb uses a Signal Impact Assessment Tool (SIAT). It categorizes signals into one of four categories: strong/moderate signal strength and similarly health impact. This SIAT has not been validated yet. For a study which explored follow-up actions of pharmacovigilance signals, a validated tool was desirable. Objectives: Validation of a Signal Impac...
Source
#1Leàn Rolfes (UG: University of Groningen)H-Index: 7
#2Sarah Wilkes (UG: University of Groningen)H-Index: 2
Last. Kees van Grootheest (UG: University of Groningen)H-Index: 22
view all 5 authors...
OBJECTIVE: To give an overview of the views of different types of reporters (patients and healthcare professionals (HCPs)) and assessors of adverse drug reactions (ADRs) on what they consider important information regarding an ADR report. METHODS: A semi-structured interview was conducted among reporters and assessors of ADRs in the Netherlands. All interviews were audiotaped and transcribed verbatim. Content analysis was used on the data. All transcripts were coded individually by two researche...
Source
#2Kees van Grootheest (UG: University of Groningen)H-Index: 22
Source
#1Linda HärmarkH-Index: 15
Last. Kees van GrootheestH-Index: 22
view all 3 authors...
#1L. HarmarkH-Index: 3
Last. Kees van GrootheestH-Index: 22
view all 3 authors...
OBJECTIVE: To demonstrate how a web-based intensive monitoring system using the patient as a source of information can be used to gather longitudinal safety data of a drug. Information about the time course of adverse drug reactions (ADRs) is often lacking. If this information would be available, it could help increase patient's adherence to drugs when experiencing an ADR. In this study, pregabalin was used as an example. DESIGN AND METHODS: First-time users of pregabalin were approached in Dutc...
#1Linda HärmarkH-Index: 15
#2Susanne Alberts (UG: University of Groningen)H-Index: 1
Last. Kees van GrootheestH-Index: 22
view all 5 authors...
Purpose Lareb Intensive Monitoring, LIM, is a non-interventional observational cohort method which follows first-time users of certain drugs during a certain period of time and collects information about adverse drug reactions, ADRs. In order for LIM to be a useful pharmacovigilance tool, it is important to know whether the LIM population is comparable to the whole population using the drug. The aim of this study is to compare the LIM diabetes population with an external diabetes reference popul...
Source
#1Linda HärmarkH-Index: 15
Last. Kees van GrootheestH-Index: 22
view all 4 authors...
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