Tatsuya Ichinohe
Tokyo Dental College
SurgeryBlood flowHemodynamicsChemistryEpinephrinePropofolMean arterial pressureSedationHeart rateMidazolamAnestheticRemifentanilLocal anestheticLidocaineFentanylBispectral indexSevofluraneAnesthesiaMedicineBlood pressure
143Publications
19H-index
1,086Citations
Publications 145
Newest
#1Ai Yamazaki (Tokyo Dental College)
#2Masataka Kasahara (Tokyo Dental College)H-Index: 10
Last. Tatsuya Ichinohe (Tokyo Dental College)H-Index: 19
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The aim of this study was to investigate the effects of end-tidal carbon dioxide tension (ETCO2) changes during remifentanil infusion on mandibular bone marrow tissue blood flow (BBF), masseter muscle tissue blood flow (MBF), mandibular bone marrow tissue oxygen tension (PbO2) and masseter muscle tissue oxygen tension (PmO2) in rabbits. Ten male tracheotomized Japan White rabbits were anesthetized and ventilated with sevoflurane. ETCO2 was adjusted to 30 mmHg. After baseline measurement, CO2 was...
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The ionotropic P2X receptor, P2X7, is believed to regulate and/or generate nociceptive pain, and pain in several neuropathological diseases. Although there is a known relationship between P2X7 receptor activity and pain sensing, its detailed functional properties in trigeminal ganglion (TG) neurons remains unclear. We examined the electrophysiological and pharmacological characteristics of the P2X7 receptor and its functional coupling with other P2X receptors and pannexin-1 (PANX1) channels in p...
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#1Moe SoedaH-Index: 1
#2Seii OhkaH-Index: 17
Last. Kazutaka IkedaH-Index: 47
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Pain sensitivity differs individually, but the mechanisms and genetic factors that underlie these differences are not fully understood. To investigate genetic factors that are involved in sensing cold pain, we applied a cold-induced pain test and evaluated protease-activated receptor 2 (PAR2/F2RL1) and transient receptor potential melastatin 8 (TRPM8), which are related to pain. We statistically investigated the associations between genetic polymorphisms and cold pain sensitivity in 461 healthy ...
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#2Nobuyuki MatsuuraH-Index: 6
Last. Tatsuya Ichinohe (Tokyo Dental College)H-Index: 19
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The objectives of this research were to investigate (a) what was the most effective infusion rate of remifentanil and (b) the degree to which sympathomimetic effects were involved with cardiovascular stimulation by using a power spectral analysis of heart rate variability (HRV). A total of 63 healthy individuals scheduled for sagittal split ramus osteotomy were enrolled and randomly allocated to 1 of 3 groups: remifentanil infusion rate of 0.1, 0.2, or 0.4 μg/kg/min. Anesthesia was maintained wi...
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#1Rie Inoue (Juntendo University)H-Index: 1
#2Daisuke Nishizawa (Institute of Medical Science)H-Index: 14
Last. Akira Kitamura (Saitama Medical University)H-Index: 8
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BACKGROUND Opioids are widely used as effective analgesics, but opioid sensitivity varies widely among individuals. The underlying genetic and nongenetic factors are not fully understood. Based on the results of our previous genome-wide association study, we investigated the effects of single nucleotide polymorphisms (SNPs) of the astrotactin 2 (ASTN2) gene on pain-related phenotypes in surgical patients. METHODS We investigated the effects of two SNPs, rs958804 T/C and rs7858836 C/T, of the AST...
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#1Ayaka Kobayashi (Tokyo Dental College)H-Index: 1
#2Masataka Kasahara (Tokyo Dental College)H-Index: 10
Last. Tatsuya Ichinohe (Tokyo Dental College)H-Index: 19
view all 6 authors...
The aim of this study was to compare changes in tissue blood flow and tissue oxygen tension in the masseter muscle and mandibular bone marrow induced by remifentanil under desflurane or sevoflurane anesthesia. Eleven male tracheotomized Japan White rabbits were anesthetized with desflurane or sevoflurane under mechanical ventilation. The order of the inhalation of desflurane or sevoflurane was randomized. Desflurane or sevoflurane was administered at 1.0 minimum alveolar concentration and remife...
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#1Tatsuya Ichinohe (Tokyo Dental College)H-Index: 19
#2Yui Akiike (Tokyo Dental College)H-Index: 1
Last. Nobuyuki Matsuura (Tokyo Dental College)H-Index: 6
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This study investigated the effects of a unilateral stellate ganglion block (SGB) on ipsilateral and contralateral masseter muscle blood flow during permissive hypercapnia. Eight male Japanese white rabbits were anesthetized with isoflurane. Observed variables included heart rate (HR), blood pressure (BP), left common carotid artery blood flow (LCBF), left and right masseter muscle tissue blood flow (LMBF and RMBF), and left femoral quadriceps muscle tissue blood flow (LQBF). Variable measuremen...
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#1Toshiyuki Handa (Tokyo Dental College)H-Index: 4
#2Tatsuya Ichinohe (Tokyo Dental College)H-Index: 19
Here, we report a case in which acupuncture combined with trigger point injection was effective in a patient with chronic myofascial pain with referred pain in the masticatory muscles. The patient was a 46-year-old woman with the chief complaint of chronic persistent pain in the region of the left mandibular first molar, which had been extracted 5 months earlier. Stellate ganglion block was performed and amitriptyline administered at another hospital, but were ineffective. At her initial visit t...
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#1Akira HirayamaH-Index: 1
#2Ken-ichi Fukuda (Tokyo Dental College)H-Index: 14
Last. Tatsuya Ichinohe (Tokyo Dental College)H-Index: 19
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Background: This study aimed to examine whether the combination of low-dose ketamine and propofol in deep sedation is clinically useful in controlling the behavior in intellectually disabled patients who are typically extremely noncooperative during dental procedures. Methods: A total of 107 extremely noncooperative intellectually disabled adult patients were analyzed. In all patients, deep sedation was performed using either propofol alone (group P) or using a combination of propofol and 0.2 mg...
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