Chi-Young Yun
Daejeon University
HemolymphInternal medicineEndocrinologyImmunoglobulin EMolecular biologyChemistryImmunologyIn vivoEotaxinHouse dust miteAtopic dermatitisCytokineBiochemistryMedicineCell cultureBiologyPharmacology
58Publications
13H-index
532Citations
Publications 58
Newest
#1Sang‐Jin JeonH-Index: 1
#2Eun Joo Kim (Daejeon University)H-Index: 8
Last. Chi-Young YunH-Index: 13
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#1Do Hyung Kim (Eulji University)H-Index: 22
#2Ji-Sook Lee (Health Science University)H-Index: 18
Last. In Sik Kim (Eulji University)H-Index: 17
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Chinese quince (Chaenomeles sinensis; CS) is known as a traditional oriental medicine for treating anaphylaxis and viral infection. Mast cells play an important role in a variety of inflammatory diseases. The inhibitory effects of CS extract on the inflammatory response of human mast cells were examined. CS extract inhibited HMC-1 cell migration in response to stem cell factor (SCF). Its mechanism is involved in the inhibition of a surface expression of c-kit binding to SCF. Tumor necrosis facto...
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#1Heung-Soo KimH-Index: 1
#2Seock-Yeon HwangH-Index: 18
Last. Chi-Young YunH-Index: 13
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#1In Sik Kim (Eulji University)H-Index: 17
#2Dong Hee Kim (Daejeon University)H-Index: 7
Last. Ji-Sook Lee (Health Science University)H-Index: 18
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(S)-(+)-decursin is a biological coumarin compound isolated from Angelica gigas Nakai. (S)-(+)-decursin and its analogue have a variety of pharmacological activities. In the present study, the anti-inflammatory effect of a (S)-(+)-decursin derivative, (S)-(+)-3-(3,4-dihydroxy-phenyl)-acrylic acid 2,2-dimethyl-8-oxo-3,4-dihydro-2H,8H-pyrano [3,2-g]-chromen-3-yl-ester (Compound 6, C6), on in vitro and in vivo atopic dermatitis was investigated. C6 suppressed the secretion of IL-6, IL-8, and monocy...
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#1Joo-Baek LeemH-Index: 2
#2Wonju JeonH-Index: 10
Last. Sang-Hee LeeH-Index: 17
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Fish form schools of various sizes, according to species or environmental conditions, to attain several advantages, such as protection from predators or to improve efficiency in searching for prey. Thus, quantifying the mechanisms of how group size affects schooling behavior may contribute to better understanding fish biology and the evolution of the collective behavior of fishes. In the present study, we explored how school size affected the behavior of medaka (Oryzias latipes) and goldfish (Ca...
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#1In Sik Kim (Eulji University)H-Index: 17
#2Gyu-Yong Song (CNU: Chungnam National University)H-Index: 19
Last. Ji-Sook Lee (Health Science University)H-Index: 18
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Abstract Aims In this study, we synthesized a novel chemical, (E)-2-(3,4-dimethoxyphenyl)-4-oxo-4H-chromen-7-yl-3-(3,4-dimethoxyphenyl) acrylate (CSH) and investigated the effect of CSH on atopic dermatitis (AD) by evaluating the anti-inflammatory effect of CSH on immune cells in vitro and on atopic dermatitis-like lesions in vivo . Main methods Human monocytic THP-1 cells and human eosinophilic EoL-1 cells were treated with house dust mite extract in the absence and presence of CSH. Nc/Nga mice...
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Abstract Streptococcus pneumoniae is an important human pathogen that causes a variety of diseases in both adults and children, such as pneumonia, bacteremia, meningitis, otitis media, and sinusitis. Despite their clinical importance, to date, there have been few proteomic studies of these strains for screening of virulence factors or diagnostic markers. In the present study, secreted proteins (secretome) of Streptococcus pneumoniae strains were enriched using ammonium sulfate precipitation and ...
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#1Ji-Sook Lee (Health Science University)H-Index: 18
#2In Sik Kim (Eulji University)H-Index: 17
Last. Chi-Young Yun (Daejeon University)H-Index: 13
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Duchesnea chrysantha belongs to the Rosaceae family and has been used traditionally for the treatment of various diseases in Korea and other parts of East Asia. This study examined the antiinflammatory effect of Duchesnea chrysantha extract (DcE) on atopic dermatitis in vitro and in vivo. DcE inhibited the production of IL-6, IL-8 and MCP-1 in THP-1 cells and the release of IL-6 and MCP-1 in EoL-1 cells after treatment with house dust mite extract. In the in vivo experiment, Nc/Nga mice were sen...
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#1Hyun Bae Kang (Daejeon University)
#2Sang Jin Jeon (Daejeon University)
Last. Chi-Young Yun (Daejeon University)H-Index: 13
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Chemical haptens like 2,4-dinitrochlorobenzene (DNCB) epicutaneously administered evoke an atopic dermatitis (AD)-like dermatitis reaction in NC/Nga mice. Bee venom (BV) has shown to have a variety of biological activities including anti-inflammatory reaction. However, the efficacy of bee venom for the allergic diseases such as atopic dermatitis, allergic rhinitis and asthma has not been completely investigated. In the present study, we examined whether treatment with bee venom suppresses AD-lik...
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#1Eun Ju Yang (Eulji University)H-Index: 10
#2Ji-Sook Lee (UPR-RP: UPRRP College of Natural Sciences)H-Index: 18
Last. In Sik Kim (Eulji University)H-Index: 17
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Abstract Aim of the study In the present study, we investigated whether the Lagerstroemia indica Linn (LI) extract has an anti-inflammatory effect on lung inflammation in ovalbumin-induced asthmatic mice. Materials and methods The LI extract was obtained from dried and powdered whole plants of LI using 80% ethanol. ELISA was performed to evaluate cytokine concentration. BALB/c mice were used as a mouse model of asthma after asthmatic induction by ovalbumin sensitization and inhalation. We examin...
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