Karolina Skonieczna-Żydecka
Pomeranian Medical University
GeneInternal medicineEndocrinologyGenotypeMicrobiomePolymorphism (computer science)Randomized controlled trialAlleleImmunologyPlaceboDepression (differential diagnoses)DiseaseBody mass indexProbioticMetabolic syndromeIntestinal permeabilityPopulationPhysiologyIncidence (epidemiology)Gut floraBioinformaticsMedicineBiologyGastroenterologyMeta-analysis
105Publications
14H-index
594Citations
Publications 110
Newest
#1Agata MiseraH-Index: 6
#2Paweł LiśkiewiczH-Index: 4
Last. Jerzy SamochowiecH-Index: 34
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Probiotics were shown to act positively on gut–brain axis signaling. We aimed to assess the effect of the administration of a new class of probiotics—psychobiotics—using data from individual psychometric scales, markers of the immune system and neuroactive metabolites. Medical databases were searched from database inception until 22 April 2021 for randomized clinical trials in clinically proven Major Depressive Disorder (MDD) patients treated with either probiotics or placebo reporting any psych...
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Last. Karol Polom (Gdańsk Medical University)H-Index: 18
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Nowadays, allogenic hematopoietic stem cell transplantation (allo-HSCT) is a curative therapy that is mainly recommended for hematologic malignancies. However, complications (such as graft-versus-host disease, mucositis, disease relapse, and infections) associated with the HSCT procedure contribute to the development of gut microbiota imbalance, gut-barrier disruption, and increased intestinal permeability. In the present narrative review, the crosstalk between gut microbiota products and intest...
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#1Justyna KikutH-Index: 3
Last. Małgorzata SzczukoH-Index: 7
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Inflammatory bowel disease (IBD) includes Crohn’s disease (CD) and ulcerative colitis (UC). The prevalence of both in pediatric populations has been constantly increasing. This study aimed to analyze the diet of adolescent patients with IBD in comparison to healthy controls and the current dietary standards for the Polish population to further their optimal supplementation regimen. The study group consisted of 53 patients (21 girls and 32 boys) with IBD (CD: n = 27; UC: n = 26) at a mean age of ...
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#1Yamile ZabanaH-Index: 19
#2Gian Eugenio Tontini (Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico)H-Index: 18
Last. Stephan Mielhke (Eppendorf (Germany))
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Background null While the exact aetiology of microscopic colitis (MC) remains unknown, a dysregulated immune response to luminal factors or medications is the most accepted pathogenesis hypothesis. null Objective null Systematic review of the pathogenesis of MC. null Methods null We applied the Joanna Briggs Institute methodologies and the PRISMA statement for the reporting of systematic reviews (PROSPERO Trial Identifier: CRD42020145008). Populations, Exposure of interest and Outcome (PEO) ques...
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#1Eliza Starz (Gdańsk Medical University)
#2Karolina Wzorek (Gdańsk Medical University)
Last. Karolina Skonieczna-Żydecka (Pomeranian Medical University)H-Index: 14
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Gastrointestinal symptoms in Crohn's disease (CD) are common and affect the quality of life of patients; consequently, a growing number of studies have been published on diet interventions in this group. The role of the gut microbiota in the pathogenesis and the progression of inflammatory bowel diseases (IBD), including CD, has been widely discussed. Mainly, a decreased abundance of Firmicutes, species of the Bifidobacterium genus, and the Faecalibacterium prausnitzii species as well as a reduc...
1 CitationsSource
OBJECTIVE The results of pioneering studies indicate that probiotics can alleviate menopausal symptoms (including cardiometabolic dysfunctions) and improve the quality of life of perimenopausal/postmenopausal women. However, the results of randomized control trials are scarce to evaluate whether the administration of probiotics could affect the balance of sex hormones during the menopause period. PATIENTS AND METHODS In this randomized, double-blind, and placebo-controlled study, 48 perimenopaus...
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#1Mariusz Kaczmarczyk (Pomeranian Medical University)H-Index: 18
#2Ulrike Löber (MDC: Max Delbrück Center for Molecular Medicine)H-Index: 6
Last. Beata Łoniewska (Pomeranian Medical University)H-Index: 6
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BACKGROUND The intestinal barrier plays an important role in the defense against infections, and nutritional, endocrine, and immune functions. The gut microbiota playing an important role in development of the gastrointestinal tract can impact intestinal permeability and immunity during early life, but data concerning this problem are scarce. METHODS We analyzed the microbiota in fecal samples (101 samples in total) collected longitudinally over 24 months from 21 newborns to investigate whether ...
1 CitationsSource
#1Anna Maria Cybulska (Pomeranian Medical University)H-Index: 1
#2Szymon Grochans (Pomeranian Medical University)H-Index: 2
Last. Elżbieta Grochans (Pomeranian Medical University)H-Index: 12
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Abstract The aim of this systematic review was to assess if cadmium and lead levels are linked to anxiety and depression. A systematic literature search was conducted to identify observational trials evaluating the impact of cadmium and lead on the incidence and phenotype of depression and anxiety. The search identified 1059 records. Overall eighteen studies comprising 28,304 participants with a female predominance (n = 19,483; 69%) were included. Cadmium and lead levels were analyzed in eight a...
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#2Agata Czarnywojtek (Poznan University of Medical Sciences)H-Index: 12
Last. Leszek KrólickiH-Index: 21
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BACKGROUND Radioiodine therapy (131I) is a standard procedure in the treatment of hyperthyroidism in the course of Graves' disease or toxic nodules. However, the use of 131I in patients with low radioiodine uptake (RAIU) may be controversial. OBJECTIVES To determine the influence of lithium carbonate (Li) on iodine kinetics. MATERIAL AND METHODS Patients with hyperthyroidism and low RAIU (< 30%) were divided into 2 groups: a Li(-) group of 305 patients not receiving Li adjuvant therapy and a Li(...
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#1Oliwia Gawlik-Kotelnicka (Medical University of Łódź)H-Index: 4
#2Anna Skowrońska (Medical University of Łódź)H-Index: 1
Last. Dominik Strzelecki (Medical University of Łódź)H-Index: 9
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There is a huge need to search for new treatment options and potential biomarkers of therapeutic response to antidepressant treatment. Depression and metabolic syndrome often coexist, while a pathophysiological overlap, including microbiota changes, may play a role. The paper presents a study protocol that aims to assess the effect of probiotic supplementation on symptoms of depression, anxiety and stress, metabolic parameters, inflammatory and oxidative stress markers, as well as fecal microbio...
1 CitationsSource