Zohar Levi
Rabin Medical Center
CancerInternal medicineSurgeryPathologyOncologyOdds ratioMucinProspective cohort studyImmunologyHelicobacter pyloriLynch syndromeColonoscopyCancer registryMSH2DiseaseFecal occult bloodBody mass indexPopulationColorectal cancerMedicineCohortBiologyGastroenterology
161Publications
28H-index
3,008Citations
Publications 162
Newest
#1Ido Laish (TAU: Tel Aviv University)H-Index: 7
#2Yael Goldberg (Rabin Medical Center)H-Index: 17
Last. Gili Levi-Reznick (Rambam Health Care Campus)
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Abstract null null Background null Routine screening for establishing Lynch syndrome (LS) in young individuals diagnosed with adenomas is not recommended due to its low yield, and limited sensitivity of the employment of immunohistochemistry for DNA mismatch-repair proteins on polyps. Hence we aimed to evaluate the yield of germline mutational analysis in diagnosis of LS in a young Israeli cohort with colorectal adenomatous polyps. null null null Methods null Data were retrospectively collected ...
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#1Rachel Gingold-Belfer (TAU: Tel Aviv University)H-Index: 5
#2Yaron Niv (National Patient Safety Foundation)H-Index: 1
Last. Doron Boltin (TAU: Tel Aviv University)H-Index: 13
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BACKGROUND AND AIM Empirical therapy for Helicobacter pylori infection is limited by increasing antibiotic resistance and suboptimal eradication rates. Studies of the relative effectiveness of susceptibility-guided therapy have produced conflicting results. We performed a systematic review and meta-analysis of randomized controlled trials (RCTs) to determine whether susceptibility-guided therapy is superior to empirical therapy for H. pylori infection. METHODS We searched articles listed in PubM...
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#1Ido Laish (Sheba Medical Center)H-Index: 1
#1Ido Laish (TAU: Tel Aviv University)H-Index: 7
Last. Yael Goldberg (Rabin Medical Center)H-Index: 17
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BACKGROUND Hereditary breast and ovarian cancer syndrome (HBOC) and Lynch syndrome (LS), the most common inherited cancer syndromes, are attributed to a single heterozygous pathogenic variant (PV) in BRCA1/2 or in a DNA MMR gene, respectively. Little is known about the phenotype in double heterozygotes who carry PVs in both genes. METHODS Carriers of double-PVs in any DNA MMR gene and BRCA1/2 attending one of three tertiary oncogenetic clinics between 1/2005 and 1/2020 were identified by databas...
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#1Naim Abu-Freha (BGU: Ben-Gurion University of the Negev)H-Index: 6
#2Lior H Katz (HUJI: Hebrew University of Jerusalem)H-Index: 1
Last. Zohar Levi (TAU: Tel Aviv University)H-Index: 28
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BACKGROUND Recently, three updated guidelines for post-polypectomy colonoscopy surveillance (PPCS) have been published. These guidelines are based on a comprehensive summary of the literature, while some recommendations are similar, different surveillance intervals are recommended after detection of specific types of polyps. AIM In this review, we aimed to compare and contrast these recommendations. METHODS The updated guidelines for PPCS were reviewed and the recommendations were compared. RESU...
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Intestinal metaplasia (IM) is an intermediate step in the progression from premalignant to malignant stages of gastric cancer (GC). The Popeye domain containing (POPDC) gene family encodes three transmembrane proteins, POPDC1, POPDC2, and POPDC3, initially described in muscles and later in epithelial and other cells, where they function in cell–cell interaction, and cell migration. POPDC1 and POPDC3 downregulation was described in several tumors, including colon and gastric cancers. We questione...
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#1Inbal Kedar (Rabin Medical Center)H-Index: 8
#2L Walsh (UW: University of Washington)
Last. Yael Goldberg (Rabin Medical Center)H-Index: 17
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Lynch syndrome is an inherited cancer predisposition syndrome caused by germline defects in any of the mismatch repair (MMR) genes. Diagnosis of carriers makes precision prevention, early detection, and tailored treatment possible. Herein we report a novel founder deletion of 18,758 bp, mediated by Alu repeats on both sides, detected in Ethiopian Jews. The deletion, which encompasses exon 9-10 of the MSH2 coding sequence, is associated mainly with early-onset MSH2/MSH6-deficient colorectal cance...
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#1Yifat Snir (Rabin Medical Center)H-Index: 3
#2Haim Leibovitzh (Rabin Medical Center)H-Index: 5
Last. Zohar Levi (TAU: Tel Aviv University)H-Index: 28
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BackgroundGastric intestinal metaplasia is a pre-cancerous condition associated with multiple factors.ObjectiveWe evaluated whether cumulative proton pump inhibitor dose is associated with the diag...
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#1Aya Bardugo (HUJI: Hebrew University of Jerusalem)H-Index: 4
#2Cole D. Bendor (HUJI: Hebrew University of Jerusalem)H-Index: 4
Last. Gilad Twig (HUJI: Hebrew University of Jerusalem)H-Index: 27
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CONTEXT The long-term risk of type 2 diabetes in adolescents with nonalcoholic fatty liver disease (NAFLD) is unclear. OBJECTIVE To assess type 2 diabetes risk among adolescents with NAFLD. DESIGN AND SETTING A nationwide, population-based study of Israeli adolescents who were examined before military service during 1997-2011 and were followed until December 31, 2016. PARTICIPANTS A total of 1,025,796 normoglycemic adolescents were included. INTERVENTIONS Biopsy or radiographic tests were prereq...
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