Hong-Tao Zhu
Chinese Academy of Sciences
TriterpenoidCytotoxicityCircular dichroismGenusOrganic chemistryChemistryGlycosideTerpenoidPhyllanthusAraliaceaeTheaceaePanax notoginsengHydrolyzable TanninHuman cancerCamellia sinensisFood scienceTraditional medicineBotanyStereochemistryBiology
74Publications
16H-index
714Citations
Publications 72
Newest
#1Hui-Chun Geng (CAS: Chinese Academy of Sciences)
#2Hong-Tao Zhu (CAS: Chinese Academy of Sciences)H-Index: 16
Last. Ying-Jun Zhang (CAS: Chinese Academy of Sciences)H-Index: 28
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Abstract null null The young leaves of Phyllanthus acidus (Euphorbiaceae) are commonly used as edible vegetables in Indonesia, Thailand, and India, and their water infusions as dieting aids for people trying to remain slim. However, it is regarded as a poisonous plant in Malaya, and current researches are insufficient to provide a conclusion on its toxicity and safety under large doses. In this study, we firstly found that the refined nonpolar extracts of P. acidus leaves showed significant cyto...
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#1Jun Yin (CAS: Chinese Academy of Sciences)
#2Hong-Tao Zhu (CAS: Chinese Academy of Sciences)H-Index: 16
Last. Ying-Jun Zhang (CAS: Chinese Academy of Sciences)H-Index: 28
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The extensive chemical investigation on the branches and leaves of Terminalia chebula var. tomentella (Combretaceae) led to the isolation of two new lignan glucosides with a furofuran skeleton, termitomenins F (1) and G (2). In addition, 19 known compounds including five lignan glucosides (3-7), six hydrolyzable tannins (8-13) and eight simple phenolics (14-21) were also identified. Their structures were determined by comprehensive spectroscopic analyses. It is noted that 8 and 9 were C-glycosid...
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#1Hui-Chun Geng (CAS: Chinese Academy of Sciences)
#2Hong-Tao Zhu (CAS: Chinese Academy of Sciences)H-Index: 16
Last. Ying-Jun Zhang (CAS: Chinese Academy of Sciences)H-Index: 28
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Phyllaciduloids E (1) and F (2), two new cleistanthane diterpenoids, were isolated from the leaves of Phyllanthus acidus (L.) Skeels (Phyllanthaceae). Their planar structures were established by spectroscopic analysis and comparison with literature values. The relative configurations of phyllaciduloids E and F were confirmed by DFT-NMR chemical shift calculations and subsequent CP3 probability methods. Phyllaciduloids E and F were evaluated for their cytotoxicity. However, no significant activit...
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#1Na LiH-Index: 27
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#1Jia-Huan ShangH-Index: 2
#2Yi-Jun QiaoH-Index: 3
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#1Xiao-Rui Zhang (CAS: Chinese Academy of Sciences)H-Index: 2
#2Yi-Jun Qiao (CAS: Chinese Academy of Sciences)H-Index: 3
Last. Ying-Jun Zhang (CAS: Chinese Academy of Sciences)H-Index: 28
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Abstract Ethnopharmacological relevance Terminalia chebula (TC), a well-known Indian Ayurvedic medicine introduced into China in Sui and Tang Dynasties, has been recorded and used medicinally as Fructus Chebulae, together with its variety tomentella (TCT) in the Chinese Pharmacopoeia. They have been also used commonly for the treatment of diabetes mellitus by Tibetan medicine. Aim of the study To investigate the main bioactive and therapeutic principles in the fruits of TCT, based on the extensi...
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#1Joseph Sakah Kaunda (CAS: Chinese Academy of Sciences)H-Index: 4
#2Xu-Jie Qin (CAS: Chinese Academy of Sciences)H-Index: 19
Last. Ying-Jun Zhang (CAS: Chinese Academy of Sciences)H-Index: 28
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Abstract Three previously undescribed pyridyl-steroidal glycoalkaloids, solanindiosides A‒C, one rare 23S,26R-hydroxylated spirostanoid saponin, and two steroidal alkaloid aglycones, solanindins A and B, derived from the acid hydrolysis of solanindiosides A‒C, were isolated from the fruits of Solanum violaceum, together with five known analogues, including two rare steroidal glycosides, two lignans and a diterpene. Structurally, they comprise a 16β-methoxy-23-deoxy-22,26-epimino-cholest-type ske...
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#1Hui-Chun Geng (CAS: Chinese Academy of Sciences)
#2Hong-Tao Zhu (CAS: Chinese Academy of Sciences)H-Index: 16
Last. Ying-Jun Zhang (CAS: Chinese Academy of Sciences)H-Index: 28
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Abstract Phytochemical investigation on the nonpolar extracts of P. acidus leaves afforded three new cleistanthane diterpenoids, named phyllanacidins A–C (1–3), in addition to three known ones (4–6). Among them, compounds 2 and 3 represent the first examples of 17-nor cleistanthane diterpenoids. Their structures including absolute configurations were elucidated on the basis of extensive spectroscopic data and single crystal X-ray diffraction analysis. All the isolated cleistanthane diterpenoids ...
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#1Joseph Sakah Kaunda (CAS: Chinese Academy of Sciences)H-Index: 4
#2Xu-Jie Qin (CAS: Chinese Academy of Sciences)H-Index: 19
Last. Ying-Jun Zhang (CAS: Chinese Academy of Sciences)H-Index: 28
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Abstract Ten previously undescribed glycosides, carissaedulosides A-J (1-10) referring to six apiosylated phenylpropanoids (1-6), one coumarin-secoiridoid hybrid (7), and three furofuran lignans (8-10) were isolated from the root barks of Carissa edulis, together with 13 known analogues (11-23). Their structures were elucidated by spectroscopic analysis, ECD computational methods, and chemical derivations for configurations of sugar moieties. The new lignan bisdesmoside, 10, exhibited significan...
1 CitationsSource
#1Na Li (CAS: Chinese Academy of Sciences)H-Index: 61
#1Na Li (CAS: Chinese Academy of Sciences)H-Index: 16
Last. Ying-Jun Zhang (CAS: Chinese Academy of Sciences)H-Index: 28
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As the subgroup of flavoalkaloids, N-ethyl-2-pyrrolidinone substituted flavan-3-ols are reported to possess various biological activities that may play important roles in the beneficial healthcare ...
2 CitationsSource