Johsuke Hara
Kanazawa University
Internal medicineSurgeryPathologyImmunologyAsthmaLung cancerCOPDInhalationChronic coughLungBronchoalveolar lavageBronchoconstrictionExhaled nitric oxideMethacholineCough variant asthmaCough reflexAnesthesiaMedicinePulmonary function testingGastroenterology
55Publications
12H-index
362Citations
Publications 56
Newest
#1Noriyuki Ohkura (Kanazawa University)H-Index: 15
#2Rie Tanaka (Kanazawa University)H-Index: 9
Last. Hideharu Kimura (Kanazawa University)H-Index: 21
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Spirometry is a crucial test used in the diagnosis and monitoring of patients with chronic obstructive pulmonary disease (COPD). Severe acute respiratory syndrome coronavirus 2 pandemic has posed numerous challenges in performing spirometry. Dynamic-ventilatory digital radiography (DR) provides sequential chest radiography images during respiration with lower doses of radiation than conventional X-ray fluoroscopy and computed tomography. Recent studies revealed that parameters obtained from dyna...
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#1Kazumasa KaseH-Index: 1
#2Satoshi WatanabeH-Index: 11
Last. Johsuke HaraH-Index: 12
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Objective The aim of this study was to identify the relationships between parameters obtained from dynamic-ventilatory digital radiography (DR) and ventilatory disorders. Methods This study comprised 273 participants with respiratory diseases who underwent spirometry and functional residual capacity measurements (104 with normal findings on spirometry as controls, 139 with an obstructive lung disorder, 30 with a restrictive lung disorder) were assessed by dynamic-ventilatory DR. Sequential chest...
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#1Hayato Koba (Kanazawa University)H-Index: 5
#2Hideharu Kimura (Kanazawa University)H-Index: 21
Last. Kazuo Kasahara (Kanazawa University)H-Index: 28
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In cancer patients, circulating cell-free DNA (cfDNA) includes tumor-derived DNA (tDNA). cfDNA has been used clinically for non-invasive gene mutation testing. The aim of this study was to characterize the features of the genetic alterations detected in cfDNA. This study included 6 patients with primary lung cancer who died due to cancer progression. Tumors were biopsied at autopsy. Genetic alteration profiles were obtained using next generation sequencing. The features of the tDNA genetic alter...
1 CitationsSource
#1Hideharu KimuraH-Index: 21
#2Takashi SoneH-Index: 12
Last. Kazuo KasaharaH-Index: 28
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Awareness of the immune-related adverse event of programmed cell death protein-1 (PD-1) inhibitor-induced pneumonitis is important. Herein, we report the clinical course of 3 patients suspected to have PD-1 inhibitor-induced pneumonitis after cessation of PD-1 inhibitor treatment. In case 1, a 62-year-old man was diagnosed with stage IVA adenocarcinoma. Nivolumab monotherapy was prescribed as second-line therapy and later discontinued due to financial reasons. Seven months after the final admini...
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#1Johsuke Hara (Kanazawa University)H-Index: 12
#2Masaki FujimuraH-Index: 53
Last. Noriyuki Ohkura (Kanazawa University)H-Index: 15
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BackgroundWe previously elucidated the fundamental pathophysiological features of various aetiologies of chronic cough, such as cough variant asthma, atopic cough, and sinobronchial syndrome. We also established a pathophysiological diagnostic procedure for aetiology identification. In this study, we aimed to disclose the aetiologies of chronic cough using the pathophysiological diagnostic procedure and to determine the outcomes of treatment administered on the basis of aetiology. Patients and M...
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#1Noriyuki Ohkura (Kanazawa University)H-Index: 15
#2Masaki FujimuraH-Index: 53
Last. Kazuo Kasahara (Kanazawa University)H-Index: 28
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Abstract Background Cough variant asthma (CVA) is the most common cause of chronic cough and responds well to bronchodilator therapy. Previous studies on methacholine -induced cough have shown that heightened cough response due to bronchoconstriction is a feature of CVA. The aim of this study was to assess Mch-induced cough as an indicator of bronchodilator-responsive cough (BRC). Methods This was a single-center retrospective study of prolonged/chronic cough cases who underwent evaluation via s...
1 CitationsSource
#2Taro YonedaH-Index: 4
Last. Kazuo Kasahara (Kanazawa University)H-Index: 28
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We presented a rare case of pulmonary arteriovenous fistula in a patient who suffered from migraine with optic aura for longer than 20 years. This case suggests that the migraine could be expected to disappear after treatment for pulmonary arteriovenous fistula.
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#1Noriyuki OhkuraH-Index: 15
#2Kazuo Kasahara (Kanazawa University)H-Index: 28
Last. Rie Tanaka (Kanazawa University)H-Index: 9
view all 14 authors...
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#1Noriyuki Ohkura (Kanazawa University)H-Index: 15
#2Kazuo Kasahara (Kanazawa University)H-Index: 28
Last. Rie Tanaka (Kanazawa University)H-Index: 9
view all 13 authors...
OBJECTIVE: The aim of this study was to determine the utility of dynamic-ventilatory digital radiography (DR) for pulmonary function assessment in patients with airflow limitation. METHODS: One hundred and eighteen patients with airflow limitation (72 patients with lung cancer before surgery, 35 patients with chronic obstructive pulmonary disease [COPD], 6 patients with asthma, and 5 patients with asthma-COPD overlap syndrome) were assessed with dynamic-ventilatory DR. The patients were instruct...
9 CitationsSource