Maxim S. Petrov
University of Auckland
Internal medicineEndocrinologySurgeryRandomized controlled trialIntensive care medicinePancreatitisAcute pancreatitisType 2 diabetesPancreatic polypeptideGlucagonPancreasDiseaseInsulinMEDLINEPrediabetesPancreatic cancerPancreatic hormonePopulationConfidence intervalDiabetes mellitusMedicineGastroenterologyMeta-analysis
154Publications
28H-index
2,154Citations
Publications 153
Newest
#1Phil A Hart (NIH: National Institutes of Health)
#2Dana K. Andersen (NIH: National Institutes of Health)H-Index: 21
Last. Mark O. Goodarzi (Cedars-Sinai Medical Center)H-Index: 67
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PURPOSE OF REVIEW Diabetes secondary to pancreatic diseases (i.e., acute pancreatitis, chronic pancreatitis, and pancreatic cancer) is increasingly studied, but remains challenging to distinguish from type 2 diabetes (T2DM). We review the clinical significance and potential biomarkers that may help differentiate these types of diabetes. RECENT FINDINGS Recent studies have identified several complications (including nonvascular) that occur more frequently in patients with diabetes secondary to ac...
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#1Sakina H. Bharmal (University of Auckland)H-Index: 9
#2Wandia Kimita (University of Auckland)H-Index: 3
Last. Maxim S. Petrov (University of Auckland)H-Index: 28
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OBJECTIVE Early identification of individuals at a high risk for metabolic derangements after an attack of acute pancreatitis (AP) is critical with a view to tertiary preventing of this disease. The aim was to investigate whether fasting pancreatic and gut hormones at baseline were predictive of future risk of new-onset prediabetes after acute pancreatitis (NOPAP) in individuals with non-necrotising AP. METHODS This was a prospective longitudinal cohort study that included 69 consecutive non-dia...
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#1Juyeon Ko (University of Auckland)H-Index: 6
#2Loren Skudder-Hill (University of Auckland)H-Index: 2
Last. Maxim S. Petrov (University of Auckland)H-Index: 28
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BACKGROUND New-onset prediabetes/diabetes after acute pancreatitis (NODAP) is the most common sequela of pancreatitis, and it differs from type 2 prediabetes/diabetes mellitus (T2DM). AIM To study the associations between circulating levels of pancreatic amylase, pancreatic lipase, chymotrypsin and fat phenotypes in NODAP, T2DM, and health. METHODS Individuals with NODAP (n = 30), T2DM (n = 30), and sex-matched healthy individuals (n = 30) were included. Five fat phenotypes (intra-pancreatic fat...
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#1Juyeon Ko (University of Auckland)H-Index: 6
#2Loren Skudder-Hill (University of Auckland)H-Index: 2
Last. Maxim S. Petrov (University of Auckland)H-Index: 28
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BACKGROUND Insulin resistance is a well-known derangement after an attack of pancreatitis but the role of dietary fat intake and intra-pancreatic fat deposition (IPFD) in it is unknown. We aimed to investigate the relationship of dietary fat intake with markers of insulin resistance in individuals after acute pancreatitis, taking into account IPFD. METHODS This was a cross-sectional study. The EPIC-Norfolk food frequency questionnaire was used to determine the habitual intake of saturated, monou...
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#1Jaelim Cho (University of Auckland)H-Index: 3
#1Jaelim Cho (University of Auckland)H-Index: 15
Last. Maxim S. Petrov (University of Auckland)H-Index: 28
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Abstract Background It is unknown whether cholecystectomy for acute pancreatitis (AP) affects the risk of post-pancreatitis diabetes mellitus (PPDM). We aimed to investigate the associations between cholecystectomy, recurrent biliary events prior to cholecystectomy, and the risk of PPDM in patients with AP. Methods Using New Zealand nationwide data from 2007 to 2016, patients with first admission for AP were identified (n = 10,870). Cholecystectomy was considered as a time-dependent exposure. Ti...
2 CitationsSource
#1Mark O. Goodarzi (NIH: National Institutes of Health)
#2Maxim S. PetrovH-Index: 28
Last. Phil A. HartH-Index: 29
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PURPOSE OF REVIEW The purpose of this review is to delineate risk factors for the development of diabetes in patients with chronic pancreatitis. The natural history including progression to diabetes and complications that develop once diabetes occurs in chronic pancreatitis is also reviewed. RECENT FINDINGS Studies have found that predictors of diabetes in chronic pancreatitis include both risk factors for type 2 diabetes (e.g., obesity, genetic variants) as well as pancreas-specific factors (e....
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Introduction The need for new drugs for diabetes is obvious. Albeit type 2 diabetes is the most common type of diabetes, it is fundamentally a disease of exclusion. Post-pancreatitis diabetes mellitus is one of the most common types of secondary diabetes. The pharmaceutical armamentarium in the field of diabetology can be broadened if the design of novel drugs is informed by pathogenetic insights from studies on post-pancreatitis diabetes mellitus. Areas covered The article provides an overview ...
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Progress in the fight against pancreatic cancer has been hampered by many factors. One of them is the inability to detect the disease early in overwhelming majority of patients. The present paper outlines a novel way in which progress could be accelerated. This includes a focus on two harbingers-post-pancreatitis diabetes mellitus and excess intra-pancreatic fat deposition-that converge at affecting the tumor macroenvironment and microenvironment specifically in the pancreas, not other organs. T...
1 CitationsSource
#1Bassam M. Abunahel (University of Auckland)H-Index: 1
#2Beau Pontre (University of Auckland)H-Index: 10
Last. Maxim S. Petrov (University of Auckland)H-Index: 28
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To systematically review published studies on the use of radiomics of the pancreas. The search was conducted in the MEDLINE database. Human studies that investigated the applications of radiomics in diseases of the pancreas were included. The radiomics quality score was calculated for each included study. A total of 72 studies encompassing 8863 participants were included. Of them, 66 investigated focal pancreatic lesions (pancreatic cancer, precancerous lesions, or benign lesions); 4, pancreatit...
3 CitationsSource
#1Sakina H. Bharmal (University of Auckland)H-Index: 9
#2Jaelim Cho (University of Auckland)H-Index: 15
Last. Maxim S. Petrov (University of Auckland)H-Index: 28
view all 6 authors...
BACKGROUND The potential of a ketone monoester (β-hydroxybutyrate; KEβHB) supplement to rapidly mimic a state of nutritional ketosis offers a new therapeutic possibility for diabetes prevention and management. While KEβHB supplementation has a glucose-lowering effect in adults with obesity, its impact on glucose control in other insulin-resistant states is unknown. OBJECTIVES The primary objective was to investigate the effect of KEβHB-supplemented drink on plasma glucose in adults with prediabe...
4 CitationsSource