Kenichi Takano
Sapporo Medical University
Downregulation and upregulationSurgeryPathologyAntibodyTight junctionImmunologyBiopsyOccludinDacryoadenitisSialadenitisDiseaseIgG4-related diseasePathogenesisClaudinBarrier functionMucous membrane of noseSignal transductionMedicineBiologyCell biology
153Publications
23H-index
1,771Citations
Publications 141
Newest
#1Keisuke Yamamoto (Sapporo Medical University)H-Index: 3
#2Makoto Kurose (Sapporo Medical University)H-Index: 10
Last. Kenichi Takano (Sapporo Medical University)H-Index: 23
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Abstract Of the schwannomas that arise from the parapharyngeal space, those in the high cervical region are particularly invasive, requiring mandibular dissection. Because these tumors are benign, however, excessive surgical invasion and postoperative neurological complications should be avoided. Postoperative dropout symptoms may be avoided by intracapsular extraction, including nerve integrity monitoring (NIM) and narrow-band imaging (NBI). Video laryngoscopy surgery is reported to be useful f...
1 CitationsSource
#1Kenichi Takano (Sapporo Medical University)H-Index: 23
#2Aya Kaizaki (Sapporo Medical University)H-Index: 1
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#1Akito Kakiuchi (Sapporo Medical University)H-Index: 3
#2Takuya Kakuki (Sapporo Medical University)H-Index: 8
Last. Takashi Kojima (Sapporo Medical University)H-Index: 44
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In human head and neck squamous cell carcinoma (HNSCC), the invasion and metastatic properties of cancer cells are promoted by junctional adhesion molecule‑A (JAM‑A) and claudin‑1; these are epithelial tight junction molecules regulated by histone deacetylases (HDACs) and transcription factor p63. HDAC expression is reportedly upregulated in HNSCC, and HDAC inhibitors suppress cancer cell proliferation by initiating proliferative arrest or apoptosis. However, little is known of the anti‑cancer m...
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#1Yuka Takumi (Sapporo Medical University)
#2Kazufumi Obata (Sapporo Medical University)H-Index: 9
Last. Kenichi Takano (Sapporo Medical University)H-Index: 23
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Abstract Sarcoma caused by radiation therapy is called radiation-induced sarcoma (RIS). This rare pathology is being encountered with increasing frequency due to the longer survival time of patients after radiation therapy. We report a case of RIS in the anterior neck of an 82-year-old man who had achieved complete response from radiation therapy for subglottic cancer 11 years earlier. He presented to our facility with an enlarged anterior cervical tumor. Contrast-enhanced computed tomography (C...
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#1Kenichi Takano (Sapporo Medical University)H-Index: 23
#2Aya Kaizaki (Sapporo Medical University)H-Index: 1
Last. Tetsuo Himi (Sapporo Medical University)H-Index: 35
view all 7 authors...
Purpose This study aims to describe the recommended equipment and procedures required for successful telefitting, based on our experience, document and evaluate patient satisfaction with telefittin...
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#1Hayato Yabe (Sapporo Medical University)H-Index: 3
#2Ryuta Kamekura (Sapporo Medical University)H-Index: 19
Last. Shingo Ichimiya (Sapporo Medical University)H-Index: 28
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AbstractObjectives: The aim of this study was to determine pathological features of T peripheral helper (Tph)-like (PD-1+CXCR5−CD4+ T) cells in IgG4-related disease (IgG4-RD).Methods: Tph-like cell...
5 CitationsSource
#1Keiju Kobayashi (Sapporo Medical University)
#2Ryuta Kamekura (Sapporo Medical University)H-Index: 19
Last. Hisashi Uhara (Sapporo Medical University)H-Index: 27
view all 8 authors...
1 CitationsSource
#1Kazufumi Obata (Sapporo Medical University)H-Index: 9
#2Ryo Miyata (Sapporo Medical University)H-Index: 7
Last. Kenichi Takano (Sapporo Medical University)H-Index: 23
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1 CitationsSource
#1Akira Yorozu (Sapporo Medical University)H-Index: 4
#2Eiichiro Yamamoto (Sapporo Medical University)H-Index: 27
Last. Hiromu Suzuki (Sapporo Medical University)H-Index: 60
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Tumor angiogenesis is an important therapeutic target in colorectal cancer (CRC). We aimed to identify novel genes associated with angiogenesis in CRC. Using RNA-sequencing analysis in normal and tumor endothelial cells (TECs) isolated from primary CRC tissues, we detected frequent upregulation of adipocyte enhancer-binding protein 1 (AEBP1) in TECs. Immunohistochemical analysis revealed that AEBP1 is upregulated TECs and stromal cells in CRC tissues. Quantitative RT-PCR analysis showed that the...
4 CitationsSource
#1Risa Yadomura (Sapporo Medical University)
#2Sumito JitsukawaH-Index: 7
Last. Tetsuo Himi (Sapporo Medical University)H-Index: 35
view all 6 authors...
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