Brij K. Gupta
University of Tennessee Health Science Center
PoloxamerClonogenic assayCancerInternal medicineDownregulation and upregulationBiomedical engineeringAnimal sciencePathologyMagnetic resonance imagingOncologyMolecular biologyNanoparticleRegulation of gene expressionMucinChemistryEcologyRange (biology)Tissue microarrayIn vitroGeographyIn vivoMUC1BiodistributionEthnoprimatologyPancreatic tumorCurcuminMacaqueMetastasisDrug deliveryPancreatic cancerBlack francolinCancer researchColorectal cancerFecesCell growthSignal transductionMedicineTranscription factorBiologyMagnetic nanoparticlesZoologyCell biologyCancer cellPharmacology
27Publications
12H-index
1,202Citations
Publications 27
Newest
#1Sanam Sane (USD: University of South Dakota)H-Index: 5
#2Ammara Abdullah (USD: University of South Dakota)H-Index: 7
Last. Khosrow Rezvani (USD: University of South Dakota)H-Index: 13
view all 13 authors...
Mortalin (mot-2) induces inactivation of the tumor suppressor p53's transcriptional and apoptotic functions by cytoplasmic sequestration of p53 in select cancers. The mot-2-dependent cytoprotective function enables cancer cells to support malignant transformation. Abrogating the p53-mot-2 interaction can control or slow down the growth of cancer cells. In this study, we report the discovery of a ubiquitin-like (UBX)-domain-containing protein, UBXN2A, which binds to mot-2 and consequently inhibit...
25 CitationsSource
#1Beatrice MorettiH-Index: 2
#2Omar F. Al-Sheikhly (UOB: University of Baghdad)H-Index: 4
Last. Filippo BarbaneraH-Index: 11
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Phylogeography of the smooth-coated otter ( Lutrogale perspicillata ): distinct evolutionary lineages and hybridization with the Asian small-clawed otter ( Aonyx cinereus )
6 CitationsSource
#1Brianne A. Beisner (UC Davis: University of California, Davis)H-Index: 16
#2Krishna N. Balasubramaniam (UC Davis: University of California, Davis)H-Index: 11
Last. Brenda McCowan (UC Davis: University of California, Davis)H-Index: 36
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There has been a recent surge in research on primate infectious disease ecology. Two major areas remain relatively unaddressed to date—the prevalence of enteric bacterial parasites and the role of anthropogenic environmental factors in parasite acquisition in commensally living primate populations. In this preliminary assessment, we address both these gaps by assessing the prevalence, and the role of anthropogenic factors in shaping this prevalence, of three enteric bacterial parasites—E . coli ...
6 CitationsSource
#1Brij K. GuptaH-Index: 12
#2Sik
Last. Meena JaggiH-Index: 36
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Mucins are the most abundant high molecular weight O-glycosylated glycoproteins present in mucus. MUC13, a member of mucin protein family, is a membrane bound mucin. MUC13 has shown to be implicated in variety of gastrointestinal cancers including cancers of salivary glands (mucoepidermoid carcinoma), esophagus (esophageal squamous cell carcinoma), stomach (gastric adenocarcinoma), liver (intrahepatic hepatocellular carcinoma), pancreatic (pancreatic ductal cell carcinoma), and colorectal cancer...
#1Giovanni Forcina (UniPi: University of Pisa)H-Index: 9
#2Monica Guerrini (UniPi: University of Pisa)H-Index: 11
Last. Filippo Barbanera (UniPi: University of Pisa)H-Index: 11
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Humans have a long history of moving wildlife that over time has resulted in unprecedented biotic homogenization. It is, as a result, often unclear whether certain taxa are native to a region or naturalized, and how the history of human involvement in species dispersal has shaped present-day biodiversity. Although currently an eastern Palaearctic galliform, the black francolin (Francolinus francolinus) was known to occur in the western Mediterranean from at least the time of Pliny the Elder, if ...
12 CitationsSource
#1Brianne A. Beisner (UC Davis: University of California, Davis)H-Index: 16
#2Allison Heagerty (UC Davis: University of California, Davis)H-Index: 4
Last. Brenda McCowan (UC Davis: University of California, Davis)H-Index: 36
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Macaques live in close contact with humans across South and Southeast Asia, and direct interaction is frequent. Aggressive contact is a concern in many locations, particularly among populations of rhesus and longtail macaques that co-inhabit urbanized cities and towns with humans. We investigated the proximate factors influencing the occurrence of macaque aggression toward humans as well as human aggression toward macaques to determine the extent to which human behavior elicits macaque aggressio...
17 CitationsSource
#1Asit Das (IVRI: Indian Veterinary Research Institute)H-Index: 6
#2M.L. SmithH-Index: 1
Last. Devendra SwarupH-Index: 30
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In order to study the effect of concentrates restriction on feed consumption, diet digestibility, and utilization of nitrogen in captive Asian elephants (Elephas maximus), two feeding trials were conducted on three juveniles, four sub-adults, and three adults. During trial I, the conventional zoo diets of juveniles, sub-adults, and adult contained 22, 17, and 16% of concentrates on dry matter (DM) basis, respectively. During trial II, the amount of concentrate was reduced by 50%. A digestion tri...
3 CitationsSource
#1Giovanni ForcinaH-Index: 9
#2Monica GuerriniH-Index: 11
Last. Filippo BarbaneraH-Index: 11
view all 11 authors...
#1Brij K. Gupta (USD: University of South Dakota)H-Index: 12
#2Diane M. MaherH-Index: 18
Last. Subhash C. Chauhan (UTHSC: University of Tennessee Health Science Center)H-Index: 49
view all 9 authors...
Background MUC13 is overexpressed and aberrantly localized in colon cancer tissue; however, the specific functions and regulation of MUC13 expression are unknown.
25 CitationsSource
#1Murali M. Yallapu (UTHSC: University of Tennessee Health Science Center)H-Index: 34
#2Sheema Khan (UTHSC: University of Tennessee Health Science Center)H-Index: 23
Last. Subhash C. Chauhan (UTHSC: University of Tennessee Health Science Center)H-Index: 49
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Abstract Prostate cancer is the most commonly diagnosed cancer disease in men in the Unites States and its management remains a challenge in everyday oncology practice. Thus, advanced therapeutic strategies are required to treat prostate cancer patients. Curcumin (CUR) is a promising anticancer agent for various cancer types. The objective of this study was to evaluate therapeutic potential of novel poly(lactic- co -glycolic acid)- CUR nanoparticles (PLGA-CUR NPs) for prostate cancer treatment. ...
141 CitationsSource