Miao Long
Shenyang Agricultural University
Internal medicineEndocrinologyMolecular biologyChemistryApoptosisTUNEL assaySuperoxide dismutaseOxidative stressZearalenoneAntioxidantMalondialdehydeGlutathione peroxidaseFood scienceGlutathioneBiochemistrySignal transductionMycotoxinBiologyCell biologyPharmacology
52Publications
16H-index
615Citations
Publications 56
Newest
#1Jia Chen (Shenyang Agricultural University)H-Index: 3
#2Zhiming Lv (Shenyang Agricultural University)
Last. Kamil Kuca (University of Hradec Králové)H-Index: 66
view all 10 authors...
Abstract null null Aflatoxin B1 is a mycotoxin that widely exists in feed and has a great impact on human and animal health. This study aimed to examine whether Bacillus amyloliquefaciens B10 protected against aflatoxin B1-induced cecal inflammation in mice. It was found that Bacillus amyloliquefaciens B10 could significantly improve the effects of AFB1 on body weight and intestinal inflammation of mice and enhance the expression of tight-junction protein. Compared with the CON group, the combin...
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#1Jing Cai (Shenyang Agricultural University)H-Index: 1
#2Rong Yan (Shenyang Agricultural University)H-Index: 1
Last. Kamil Kuca (University of Hradec Králové)H-Index: 66
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With increased popular awareness of food safety and environmental protection, plant essential oil has attracted interest due to the absence of residue, its high efficiency, antioxidant, immune regulation, antibacterial, insecticidal, and other advantages. Their application in degradation and elimination of mycotoxin toxicity has attracted increasing attention. This paper reviews the structure, antibacterial activity, antibacterial mechanism, and toxic effects of essential oils. The inhibitory ef...
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#1Jia Chen (Shenyang Agricultural University)H-Index: 3
#2Jun Wen (Shenyang Agricultural University)
Last. Miao Long (Shenyang Agricultural University)H-Index: 16
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Fumonisin B1 (FB1), belonging to the member of fumonisins, is one of the most toxic mycotoxins produced mainly by Fusarium proliferatum and Fusarium verticillioide. FB1 has caused extensive contamination worldwide, mainly in corn, rice, wheat, and their products, while it also poses a health risk and is toxic to animals and human. It has been shown to cause oxidative stress, endoplasmic reticulum stress, cellular autophagy, and apoptosis. This review focuses on the current stage of FB1 contamina...
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#1Zhiming Lv (Shenyang Agricultural University)
#2Dongwei Xiong (Shenyang Agricultural University)
Last. Zeliang Chen (Shenyang Agricultural University)
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As the main pathogen threatening human and animal health, viruses can affect the immunity and metabolism of bodies. There are innate microbial barriers in the digestive tract of the body to preserve the homeostasis of the animal body, which directly or indirectly influences the host defence against viral infection. Understanding the interaction between viruses and intestinal microbiota or probiotics is helpful to study the pathogenesis of diseases. Here, we review recent studies on the interacti...
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#1Jia Chen (Shenyang Agricultural University)H-Index: 3
#2Mingyang Wang (Shenyang Agricultural University)H-Index: 8
Last. Miao Long (Shenyang Agricultural University)H-Index: 16
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Zearalenone (ZEA) is a mycotoxin with estrogenic activity whose main effect is to impair the reproductive systems of animals. It leads to reproductive disorders in livestock and thus causes serious losses to agriculture and animal husbandry. This study aims to examine whether ZEA induces toxicity in Leydig cells through the PI3K/AKT signaling pathway and also to investigate the role played by the upstream phosphatase and tensin homolog (PTEN) gene. An adenovirus vector model was constructed to i...
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#6Miao Long (Shenyang Agricultural University)H-Index: 16
Harmful fungi in nature not only cause diseases in plants, but also fungal infection and poisoning when people and animals eat food derived from crops contaminated with them. Unfortunately, such fungi are becoming increasingly more resistant to traditional synthetic antifungal drugs, which can make prevention and control work increasingly more difficult to achieve. This means they are potentially very harmful to human health and lifestyle. Antifungal peptides are natural substances produced by o...
1 CitationsSource
#1Yeqi Zhao (Shenyang Agricultural University)
#2Tiancheng Wang (Shenyang Agricultural University)H-Index: 1
Last. Kamil Kuca (University of Hradec Králové)H-Index: 66
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Abstract Aflatoxin B1(AFB1) widely exists in food and feed, which seriously endangers human and animal health. How to detoxify AFB1 is a research hotspot at present. This study attempts to use the Bacillus amyloliquefaciens B10, one of probiotics strain as the research object to ascertain whether it can alleviate the kidney injury induced by AFB1 in mice and its mechanism. Fifty-six mice were divided into four groups (control, AFB1, AFB1 + B10, and B10). The mice that received intragastric admin...
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#1Xiaotong Li (Shenyang Agricultural University)
#2Zhiming Lv (Shenyang Agricultural University)
Last. Kamil Kuca (University of Hradec Králové)H-Index: 66
view all 7 authors...
Abstract Aflatoxin B1 (AFB1) is a mycotoxin often found in food and livestock feed. It can affect human and animal health and is especially damaging to the liver. This study aims to evaluate whether Bacillus amyloliquefaciens (hereafter referred to as B. amyloliquefaciens) B10 can alleviate the toxic effects of AFB1 and, if so, what mechanism is responsible for its action. Specific pathogen-free (SPF) Kunming mice (5–6 weeks old) were divided into four groups (Control, AFB1, B10 strain, and AFB1...
3 CitationsSource
#1Jia Chen (Shenyang Agricultural University)H-Index: 3
#2Zhen Wei (Shenyang Agricultural University)H-Index: 1
Last. Kamil Kuca (University of Hradec Králové)H-Index: 66
view all 6 authors...
Fumonisin B1 (FB1) is a toxic secondary metabolite produced by the Fusarium molds that can contaminate food and feed. It has been found that FB1 can cause systemic toxicity, including neurotoxicity, hepatotoxicity, nephrotoxicity and mammalian cytotoxicity. This review addresses the toxicity studies carried out on FB1 and outlines the probable mechanisms underlying its immunotoxicity, reproductive toxicity, joint toxicity, apoptosis, and autophagy. In the present work, the research progress of F...
4 CitationsSource
#1Yun Guan (Shenyang Agricultural University)H-Index: 1
#2Jia Chen (Shenyang Agricultural University)H-Index: 3
Last. Kamil Kuca (University of Hradec Králové)H-Index: 66
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Mycotoxin contamination causes significant economic loss to food and feed industries and seriously threatens human health. Aflatoxins (AFs) are one of the most harmful mycotoxins, which are produced by Aspergillus flavus, Aspergillus parasiticus, and other fungi that are commonly found in the production and preservation of grain and feed. AFs can cause harm to animal and human health due to their toxic (carcinogenic, teratogenic, and mutagenic) effects. How to remove AF has become a major proble...
3 CitationsSource