John McCaffrey
Mater Misericordiae University Hospital
CancerInternal medicineRadiologySurgeryPathologyOncologyStage (cooking)ChemotherapyImmunotherapyDiseaseProstate cancerIrishDocetaxelPopulationIn patientIncidence (epidemiology)Cancer researchColorectal cancerBreast cancerClinical trialMedicineGastroenterology
Publications 124
#1Lisa Mary PriorH-Index: 3
#2Richard O'Dwyer (University Hospital Galway)
Last. Elly Hanis Che OthmanH-Index: 1
view all 47 authors...
Purpose null Pregnancy-associated breast cancer (PABC) is defined as breast cancer diagnosed during the gestational period (gp-PABC) or in the first postpartum year (pp-PABC). Despite its infrequent occurrence, the incidence of PABC appears to be rising due to the increasing propensity for women to delay childbirth. We have established the first retrospective registry study of PABC in Ireland to examine specific clinicopathological characteristics, treatments, and maternal and foetal outcomes. n...
#1Darren Cowzer (Mater Misericordiae University Hospital)
#2Karen M Mulligan (Mater Misericordiae University Hospital)H-Index: 1
Last. John McCaffrey (Mater Misericordiae University Hospital)H-Index: 16
view all 6 authors...
Primary clear cell adenocarcinoma of the urethra is extremely rare. Given the rarity of these tumours there is no high-level evidence available to guide treatments. Localized disease is typically t...
#1Christopher Sweeney (Harvard University)H-Index: 77
#2Andrew J. Martin (USYD: University of Sydney)H-Index: 104
Last. New Zealand UrogenitalH-Index: 2
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Men who initially present with localized prostate cancer and later develop metachronous metastases have a better prognosis than men with de novo metastatic disease and often have a low burden of disease on conventional imaging. Some have disease amenable to metastasis-directed therapy for lymph node or bone metastases, a strategy used by some because no documented overall survival (OS) benefit of combination systemic therapy in this setting. We report data for patients prospectively classified a...
#3John McCaffrey (Mater Misericordiae University Hospital)H-Index: 16
#10Ann E Brannigan (Mater Misericordiae University Hospital)
#5John McCaffrey (Mater Misericordiae University Hospital)H-Index: 16
#1Hailey Kathryn Carroll (Mater Misericordiae University Hospital)
#2Tom Nolis (Mater Misericordiae University Hospital)
Last. John McCaffrey (Mater Misericordiae University Hospital)H-Index: 16
view all 5 authors...
Leydig cell tumours (LCT) are rare testicular neoplasms that usually follow a benign clinical course. Due to the aggressive, difficult-to-treat nature of metastatic disease arising from a small percentage of LCTs, it is imperative to understand and recognize how to identify those tumours which exhibit features that predict malignant behaviour in order to guide initial surgical and oncological management. By using the well-described high-risk histopathological features of Leydig cell tumours as g...
#1Lisa Mary PriorH-Index: 3
Last. Catherine M. KellyH-Index: 22
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Background: Advancement in the treatment of metastatic estrogen receptor positive (ER+) breast cancer has led to the introduction of CDK4/6 inhibitors such as Palbociclib, which are associated with reversal of endocrine resistance and delayed requirement for chemotherapy. Clinical trials to date have demonstrated improved survival outcomes for patients on these agents. The objective of this study was to evaluate their role in a real-world setting. Methods: We performed a retrospective multicentr...
#1David O'Reilly (Mater Misericordiae University Hospital)H-Index: 2
#2Hailey Kathryn Carroll (Mater Misericordiae University Hospital)
Last. M. Higgins (Mater Misericordiae University Hospital)H-Index: 6
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Background The COVID-19 pandemic has resulted in radical changes in the delivery of healthcare worldwide. Our oncology service (at an Irish national cancer centre) rapidly transitioned to the use of telemedicine or virtual clinics (VC) to minimise potential risk of exposure to COVID-19 amongst an immunosuppressed, high-risk population. Our study aimed to evaluate the use of VC in this setting. Methods An 18-point questionnaire was designed to investigate the patient experience of VC during the C...
1 CitationsSource
Background:Systemic anti-cancer treatment (SACT) can improve symptoms and survival in patients with incurable cancer but there may be harmful consequences. Information regarding the use of SACT at ...
1 CitationsSource