Arndt Hartmann
University of Erlangen-Nuremberg
CancerPathologyOncologyMolecular biologyTissue microarrayImmunohistochemistryCystectomyRenal cell carcinomaCarcinomaMetastasisProstate cancerBladder cancerGynecologyMutationCancer researchColorectal cancerBreast cancerCarcinogenesisMedicineBiology
Publications 1034
#2Fredrik Liedberg (Lund University)H-Index: 28
Last. Liang Cheng (IU: Indiana University)H-Index: 72
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Abstract Context Grading is the mainstay for treatment decisions for patients with non–muscle-invasive bladder cancer (NMIBC). Objective To determine the requirements for an optimal grading system for NMIBC via expert opinion. Evidence acquisition A multidisciplinary working group established by the International Society of Urological Pathology reviewed available clinical, histopathological, and molecular evidence for an optimal grading system for bladder cancer. Evidence synthesis Bladder cance...
#1Hiresh AyoubianH-Index: 3
#2Joana HeinzelmannH-Index: 8
Last. Kerstin JunkerH-Index: 39
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Although microRNAs are described as promising biomarkers in many tumor types, little is known about their role in PSCC. Thus, we attempted to identify miRNAs involved in tumor development and metastasis in distinct histological subtypes considering the impact of HPV infection. In a first step, microarray analyses were performed on RNA from formalin-fixed, paraffin-embedded tumor (22), and normal (8) tissue samples. Microarray data were validated for selected miRNAs by qRT-PCR on an enlarged coho...
#1Sonia L. Villegas (Humboldt University of Berlin)H-Index: 4
Last. Sibylle LoiblH-Index: 74
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Abstract Aim To evaluate HER2-negative breast cancer (BC) with a low hormone receptor (HR) expression, with regard to pathological complete response (pCR) and survival, in comparison to triple-negative BC (TNBC) and strong HR-positive BC. Methods We compared negative [oestrogen (ER) and progesterone receptor (PR) Results Ninety-four (3.4%) patients had low HR-positive tumours, 1769 (64.0%) had strong HR-positive tumours, and 902 (32.6%) had TNBC. There were no significant differences in pCR rate...
#1Oliver J. OttH-Index: 30
#1O.J. Ott (University of Tübingen)H-Index: 8
Last. Rainer Fietkau (University of Tübingen)H-Index: 1
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Background: To prospectively analyze feasibility and pathological complete response (pCR) rates of neoadjuvant chemoradiotherapy combined with regional hyperthermia (RHT) in patients with locally advanced (LARC) or recurrent (LRRC) rectal cancer. Methods: between 2012 and 2018, 111 patients with UICC stage IIB-IV or any locally recurrent rectal cancer were included (HyRec-Trial, Identifier: NCT01716949). Patients received radiotherapy with concurrent 5-Fluororuracil (5-FU)/Cap...
#1Kerstin AmannH-Index: 47
#1Kerstin AmannH-Index: 54
Last. Arndt HartmannH-Index: 81
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Bei einer schweren Coronavirus-Erkrankung-2019 (COVID-19) ist neben der Lungenerkrankung selbst das akute Nierenversagen (ANV) eine der haufigsten und schwerwiegendsten Komplikationen. Das SARS-CoV-2-Virus konnte hierbei auch in der Niere nachgewiesen werden. Patienten mit chronischen Nierenerkrankungen (CKD), dialysepflichtige sowie v. a. nierentransplantierte Patienten scheinen eine besonders vulnerable Population darzustellen. Die zunehmende Anzahl SARS-CoV-2-infizierter Patienten hat das Int...
1 CitationsSource
#2Abbas AgaimyH-Index: 45
Last. Michael ViethH-Index: 72
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1 CitationsSource
#1Kerstin AmannH-Index: 47
#1Kerstin AmannH-Index: 54
Last. Arndt HartmannH-Index: 81
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Apart from pulmonary disease, acute kidney injury (AKI) is one of the most frequent and most severe organ complications in severe coronavirus disease 2019 (COVID-19). The SARS-CoV­2 virus has been detected in renal tissue. Patients with chronic kidney disease (CKD) before and on dialysis and specifically renal transplant patients represent a particularly vulnerable population. The increasing number of COVID-19 infected patients with renal involvement led to an evolving interest in the analysis o...
1 Citations
#1Abbas AgaimyH-Index: 45
#2Robert StoehrH-Index: 39
Last. Thomas CramerH-Index: 1
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Porocarcinoma (synonym: malignant eccrine poroma) is a rare aggressive carcinoma type with terminal sweat gland duct differentiation. The squamous variant of porocarcinoma is even less frequent and might be indistinguishable from conventional squamous cell carcinoma (SCC). We herein describe the first case of a carcinoma presenting as a primary parotid gland malignancy in a 24-year-old male without any other primary tumor. Total parotidectomy and neck dissection were performed followed by adjuva...
2 CitationsSource
#2Markus EcksteinH-Index: 11
Last. Sarina K. MuellerH-Index: 9
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Objectives: The aim of this study was to assess the number of tumour-infiltrating lymphocytes (TILs) and the expression of Programmed Cell Death 1 Ligand 1 (PD-L1) in Acinic Cell Carcinoma (AciCC) of the salivary glands, to enable a correlation with clinico-pathological features and to analyse their prognostic impact. Methods: This single centre retrospective study represents a cohort of 36 primary AciCCs with long-term clinical follow-up. Immunohistochemically defined immune cell subtypes, i.e....
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