Vikram Deshpande
University of Utah
Ultimate tensile strengthFinite element methodPathologyDislocationComposite materialMaterials scienceAutoimmune pancreatitisPancreasDiseaseIgG4-related diseaseCompressive strengthCancer researchCarbon nanotubeMechanicsStructural engineeringMedicinePlasticitySandwich-structured compositeBiologyGastroenterology
Publications 812
#1Su Kong Chong (UofU: University of Utah)H-Index: 12
#2Vikram Deshpande (UofU: University of Utah)H-Index: 121
Abstract Three-dimensional (3D) topological insulators (TIs) have generated tremendous research interest over the past decade due to their topologically-protected surface states with linear dispersion and helical spin texture. The topological surface states offer an important platform to realize topological phase transitions, topological magnetoelectric effects and topological superconductivity via 3D TI-based heterostructures. In this review, we summarize the key findings of magneto and quantum...
#1U. Roy (University of Cambridge)
#1Ushasi Roy (University of Cambridge)H-Index: 4
Last. Vikram Deshpande (University of Cambridge)H-Index: 121
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Abstract The formation of dendrites within the solid-state electrolyte of a Lithium (Li) ion battery is exacerbated by the presence of voids at the interface between the electrolyte and the Li anode. It is assumed that voids initiate and grow by the focussing of Li flux at the periphery of pre-existing small imperfections along the interface between the solid electrolyte and Li anode. Void growth in the Li anode, driven by stripping of the L i + ions from the anode, is accompanied by creep withi...
#1Shalin S. Patel (WashU: Washington University in St. Louis)H-Index: 3
#1Shalin S Patel (WashU: Washington University in St. Louis)
Last. Joseph H. SchwabH-Index: 43
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Background There are no effective systemic therapies for chordoma. The recent successes of immunotherapeutic strategies in other cancers have resulted in a resurgence of interest in using immunotherapy in chordoma. These approaches rely on a functional interaction between the host's immune system and the expression of tumor peptides via the human leukocyte antigen (HLA) Class I antigen. It is not known whether chordoma cells express the HLA Class I antigen. Questions/purposes (1) Do chordoma tum...
#1Yasmeen Z. Qwaider (Harvard University)H-Index: 2
#2Naomi M. Sell (Harvard University)H-Index: 8
Last. David H. Berger (Harvard University)H-Index: 75
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INTRODUCTION Tumor border configuration (TBC) is a prognostic factor in colorectal adenocarcinoma; however, the significance of TBC is not well-documented in colon adenocarcinoma alone. OBJECTIVE Our aim was to study the effect of TBC on overall and disease-free survival in stage II and III colon adenocarcinoma. METHODS We included patients with stage II and III colon adenocarcinoma who were surgically treated at a tertiary medical center between 2004 and 2015, to ensure long-term follow-up. Pat...
1 CitationsSource
#1Anne B. Hu (Harvard University)H-Index: 1
#2William Tan (Harvard University)H-Index: 5
Last. Ashwin N. Ananthakrishnan (Harvard University)H-Index: 76
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Abstract Background & Aims Goals of treatment for Crohn’s disease (CD) are clinical and endoscopic remission. It is not clear whether histologic markers of healing associate with endoscopic remission in patients with CD. Methods We identified patients with CD from a single institutional registry, and collected data from 129 patients (46.5% female; mean age 25 y; mean CD duration 14.5 y) who underwent colonoscopy evaluation and had simple endoscopic scores for CD below 3 (the definition of endosc...
3 CitationsSource
#1Andrea Vigliotti (University of Cambridge)H-Index: 11
#2Siamak Soleymani Shishvan (University of Tabriz)H-Index: 11
Last. Vikram Deshpande (University of Cambridge)H-Index: 121
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We have analysed the response of cells on a bed of micro-posts idealized as a Winkler foundation using a homeostatic mechanics framework. The framework enables quantitative estimates of the stochastic response of cells along with the coupled analysis of cell spreading, contractility and mechano-sensitivity. In particular the model is shown to accurately predict that: (i) the extent of cell spreading, actin polymerisation as well as the traction forces that cells exert increase with increasing st...
1 CitationsSource
#1Vikram Deshpande (University of Cambridge)H-Index: 121
#2Antonio DeSimoneH-Index: 43
Last. Pierre Recho (UGA: University of Grenoble)H-Index: 12
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Abstract While it is commonly observed that the shape dynamics of mammalian cells can undergo large random fluctuations, theoretical models aiming at capturing cell mechanics often focus on the deterministic part of the motion. In this paper, we present a framework that couples an active gel model of the cell mechanical scaffold with the complex cell metabolic system stochastically delivering the chemical energy needed to sustain an active stress in the scaffold. Our closure assumption setting t...
#1Neda Lotfizadeh (UofU: University of Utah)H-Index: 4
#2Mitchell J. Senger (OSU: Oregon State University)H-Index: 2
Last. Vikram Deshpande (UofU: University of Utah)H-Index: 121
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Inflammatory myofibroblastic tumor (IMT) is a distinctive fibroblastic and myofibroblastic spindle cell neoplasm with an accompanying inflammatory cell infiltrate and frequent receptor tyrosine kinase activation at the molecular level. The tumor may recur and rarely metastasizes. IMT is rare in the head and neck region, and limited information is available about its clinicopathologic and molecular characteristics in these subsites. Therefore, we analyzed a cohort of head and neck IMTs through a ...
Immune checkpoint inhibitors target checkpoint proteins with the goal of reinvigorating the host immune system and thus restoring antitumor response. With the dramatic increase in the use of checkpoint inhibitors for cancer treatment, surgical pathologists have assumed a major role in predicting the therapeutic efficacy (score based on programmed cell death ligand 1 immunohistochemistry and mismatch repair protein loss) as well as diagnosing the complications associated with these medications. I...