T. Laing
Royal College of Surgeons in Ireland
PathologyPathologicalEndotheliumVascular diseaseDiseaseWound healingPathogenesisEndothelial dysfunctionDiabetes mellitusBioinformaticsMedicine
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Summary The global burden of diabetes is attributed to its multiple associated complications including impaired wound healing which can ultimately result in amputation. Peripheral vascular disease, infection, neuropathy and abnormal local cellular and cytokine activity are some of the traditionally cited pathological instigators of defective diabetic wound repair. Despite intensive research and subsequent advances in diabetic wound care technology a single treatment with measurable clinical impa...
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