Arezou Khosroshahi
Emory University
Internal medicineSurgeryPathologyRheumatologyImmunologyBiopsyRetroperitoneal fibrosisEosinophiliaAortitisAutoimmune pancreatitisSystemic diseasePrednisonePancreasDiseaseIgG4-related diseaseFibrosisRituximabLymphoplasmacytic InfiltrateMedicineGastroenterology
53Publications
30H-index
6,423Citations
Publications 56
Newest
#1Timothy Arleo (Emory University)
#2David Tong (Emory University)H-Index: 5
Last. Arezou Khosroshahi (Emory University)H-Index: 30
view all 5 authors...
OBJECTIVE: To determine clinical course and outcomes in rheumatic disease patients with coronavirus disease 2019 (COVID-19) and compare results to uninfected patients. METHODS: We conducted a case cohort study of autoimmune disease patients with COVID-19 (confirmed by severe acute respiratory syndrome coronavirus 2 PCR) from February 1, 2020, to July 31, 2020, and compared them in a 1:3 ratio with uninfected patients who were matched based on race, age, sex, and comorbidity index. Patient demogr...
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#1Timothy Arleo (Emory University)
#2David Tong (Emory University)H-Index: 5
Last. Arezou Khosroshahi (Emory University)H-Index: 30
view all 5 authors...
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Last. Elad SharonH-Index: 22
view all 22 authors...
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#1Ecaterina Ileana Dumbrava (University of Texas MD Anderson Cancer Center)H-Index: 6
#2Maria E. Suarez-Almazor (University of Texas MD Anderson Cancer Center)H-Index: 64
Last. Hussein Abdul-Hassan Tawbi (University of Texas MD Anderson Cancer Center)H-Index: 23
view all 20 authors...
1 CitationsSource
#1Laura P. Kimble (Emory University)H-Index: 15
#2Sandra B. Dunbar (Emory University)H-Index: 41
Last. Arezou Khosroshahi (Emory University)H-Index: 30
view all 6 authors...
Source
#1Zachary S. Wallace (Harvard University)H-Index: 25
#2Ray NadenH-Index: 6
Last. John H. Stone (Harvard University)H-Index: 76
view all 24 authors...
OBJECTIVE: IgG4-related disease (IgG4-RD) can cause fibroinflammatory lesions in nearly any organ. Correlation among clinical, serologic, radiologic, and pathologic data is required for diagnosis. This work was undertaken to develop and validate an international set of classification criteria for IgG4-RD. METHODS: An international multispecialty group of 86 physicians was assembled by the American College of Rheumatology (ACR) and the European League Against Rheumatism (EULAR). Investigators use...
49 CitationsSource
#1Zachary S. Wallace (Harvard University)H-Index: 25
#2Ray Naden (McMaster University)H-Index: 6
Last. John H. Stone (Harvard University)H-Index: 76
view all 20 authors...
IgG4-related disease (IgG4-RD) can cause fibroinflammatory lesions in nearly any organ. Correlation among clinical, serological, radiological and pathological data is required for diagnosis. This work was undertaken to develop and validate an international set of classification criteria for IgG4-RD. An international multispecialty group of 86 physicians was assembled by the American College of Rheumatology (ACR) and the European League Against Rheumatism (EULAR). Investigators used consensus exe...
99 CitationsSource
#1Daniel J. Wallace (Cedars-Sinai Medical Center)H-Index: 79
Last. Thierry DervieuxH-Index: 16
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Objective We compared the physician-assessed diagnostic likelihood of SLE resulting from standard diagnosis laboratory testing (SDLT) to that resulting from multianalyte assay panel (MAP) with cell-bound complement activation products (MAP/CB-CAPs), which reports a two-tiered index test result having 80% sensitivity and 86% specificity for SLE. Methods Patients (n=145) with a history of positive antinuclear antibody status were evaluated clinically by rheumatologists and randomised to SDLT arm (...
6 CitationsSource
#1Christopher D. Scharer (Emory University)H-Index: 21
#2Emily L. Blalock (Emory University)H-Index: 4
Last. Jeremy M. Boss (Emory University)H-Index: 62
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Systemic lupus erythematosus (SLE) is characterized by the expansion of extrafollicular pathogenic B cells derived from newly activated naive cells. Although these cells express distinct markers, their epigenetic architecture and how it contributes to SLE remain poorly understood. To address this, we determined the DNA methylomes, chromatin accessibility profiles and transcriptomes from five human B cell subsets, including a newly defined effector B cell subset, from subjects with SLE and health...
40 CitationsSource
#1Joan T. Merrill (OMRF: Oklahoma Medical Research Foundation)H-Index: 69
#2Joshua JuneH-Index: 1
Last. Debra ZackH-Index: 24
view all 14 authors...
Background: XmAb5871 is a humanized anti-CD19 antibody Fc-engineered for increased affinity to FcγRIIb. Co-ligation of CD19 and FcγRIIb inhibits B lineage cells key to SLE pathogenesis. Objectives: This Phase 2 study was designed to minimize background medications and placebo responses to improve interpretation of a small trial in a complex, heterogenous disease. Methods: SLE patients were enrolled with active disease, ameliorated during screening with ≥160 mg of IM Depo-Medrol. Improvement was ...
4 CitationsSource
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