Kwong-Sak Leung
The Chinese University of Hong Kong
Evolutionary computationGenetic programmingChoquet integralAlgorithmMachine learningEvolutionary programmingData miningMathematical optimizationArtificial intelligenceEvolutionary algorithmBayesian networkMathematicsComputer scienceInductive programmingFuzzy logicComputational biologyCluster analysisTheoretical computer scienceBiologyGenetic algorithm
360Publications
41H-index
5,535Citations
Publications 351
Newest
#1Xueyan LiuH-Index: 5
#2Yong XuH-Index: 1
Last. Lixin ChengH-Index: 11
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Moonlighting proteins provide more options for cells to execute multiple functions without increasing the genome and transcriptome complexity. Although there have long been calls for computational methods for the prediction of moonlighting proteins, no method has been designed for determining moonlighting long noncoding ribonucleicacidz (RNAs) (mlncRNAs). Previously, we developed an algorithm MoonFinder for the identification of mlncRNAs at the genome level based on the functional annotation and...
5 CitationsSource
#1Dan HuangH-Index: 1
Last. Nelson Ls Tang (CUHK: The Chinese University of Hong Kong)H-Index: 2
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Vaccination is a common and efficient means to reduce the mortality and morbidity of emerging infectious diseases. Among responders, injected antigen induces acquired immunity pathways and leads to the final production of antigen-specific antibodies. The whole process may take weeks to months, depending on the antigen. Typically, seroconversion to influenza vaccine is expected after one month with a responder rate of ~50%. An early biomarker to predict response is desirable. Peripheral blood gen...
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#1Lixin Cheng (CUHK: The Chinese University of Hong Kong)H-Index: 11
#2Yonglun Zeng (CUHK: The Chinese University of Hong Kong)H-Index: 13
Last. Liwen Jiang (CUHK: The Chinese University of Hong Kong)H-Index: 50
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Last. Lixin ChengH-Index: 11
view all 7 authors...
#1Pak-Kan Wong (CUHK: The Chinese University of Hong Kong)H-Index: 4
#2Man Leung Wong (Lingnan University)H-Index: 25
Last. Kwong-Sak Leung (CUHK: The Chinese University of Hong Kong)H-Index: 41
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Source
#1K.F. LeeH-Index: 9
#2Kwong-Sak LeungH-Index: 41
Last. Man Hon WongH-Index: 22
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In this study, we looked for potential gene-gene interaction in susceptibility to schizophrenia by an exhaustive searching for SNP-SNP interactions in 3 GWAS datasets (phs000021:phg000013, phs000021:phg000014, phs000167) using our recently published algorithm. The search space for SNP-SNP interaction was confined to 8 biologically plausible ways of interaction under dominant-dominant or recessive-recessive modes. First, we performed our search of all pair-wise combination of 729,454 SNPs after f...
1 CitationsSource
#1Xue-Yan Liu (Southern University of Science and Technology)
#2Xubin Zheng (CUHK: The Chinese University of Hong Kong)H-Index: 1
Last. Lixin Cheng (Southern University of Science and Technology)H-Index: 2
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4 CitationsSource
#1Hongru WangH-Index: 1
#2Xiangru TangH-Index: 1
Last. Kam-Fai Wong (CUHK: The Chinese University of Hong Kong)H-Index: 33
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This paper describes our system submitted to task 4 of SemEval 2020: Commonsense Validation and Explanation (ComVE) which consists of three sub-tasks. The task is to directly validate the given sentence whether or not it makes sense and require the model to explain it. Based on BERTarchitecture with a multi-task setting, we propose an effective and interpretable "Explain, Reason and Predict" (ERP) system to solve the three sub-tasks about commonsense: (a) Validation, (b)Reasoning, and (c) Explan...
2 Citations
#1Pengfei LiuH-Index: 4
#2Xubin ZhengH-Index: 1
Last. Kwong-Sak LeungH-Index: 41
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