Ciro Franzese
Humanitas University
CancerInternal medicineRadiologySurgeryOncologyUnivariate analysisRetrospective cohort studyLung cancerHead and neck cancerChemotherapyCarcinomaLungConcomitantProstate cancerRadiosurgeryProgression-free survivalToxicityStereotactic body radiation therapyNuclear medicineRadiation therapyMedicine
169Publications
19H-index
1,100Citations
Publications 168
Newest
#1Isacco Desideri (UniFI: University of Florence)H-Index: 17
#2Carlotta Becherini (UniFI: University of Florence)H-Index: 9
Last. Pierluigi Bonomo (UniFI: University of Florence)H-Index: 19
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Locally advanced Head and neck squamous cell carcinoma (SCCHN) represents a common oncologic pathology in older adults (OA). While radiotherapy represents a cornerstone in this context, it is unclear what is the optimal radiation regimen for SCCHN in the palliative setting, especially for OA. This article addresses issues related to palliative radiotherapy (PRT) in this setting with a focus on treatment modalities and toxicity. We also explore the use of quality of life and geriatric assessment ...
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#1Luca TriggianiH-Index: 15
#2Rosario MazzolaH-Index: 19
Last. Stefano Maria MagriniH-Index: 25
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The aim of the present study was to explore the potential impact of upfront metastases-directed therapy (MDT) in terms of prolongation of castration-sensitive phase in a series of oligorecurrent castration-sensitive prostate cancer (PC) patients. The present article is a multicenter retrospective study. The population of interest was castrate-sensitive oligorecurrent PC, defined as the presence of 1-3 uptakes in non-visceral sites such as bones or nodes detected by means of 18F-Choline PET/CT or...
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#1Mauro LoiH-Index: 13
#2Davide FranceschiniH-Index: 19
Last. Marta ScorsettiH-Index: 44
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The use of Stereotactic Body Radiotherapy (SBRT) is controversial in Ultra-Central lung tumors, a subset of central lung tumors characterized by proximity to critical mediastinal structures. This is of interest in oligometastatic (≤3 metastases) patients, who can yield survival benefit from local treatments. The aim of our study is to assess the determinants of efficacy and toxicity in this setting. Clinical and dosimetric parameters were reviewed in a cohort of oligometastatic patients treated ...
2 CitationsSource
#1Pietro MancosuH-Index: 33
#1P. MancosuH-Index: 9
Last. Marta Scorsetti (Humanitas University)H-Index: 44
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Abstract Purpose Failure mode effect analysis (FMEA) is a proactive methodology that allows one to analyze a process, regardless of whether an adverse event occurs. In our radiation therapy (RT) department, a first FMEA was performed in 2009. In this paper we critically re-evaluate the RT process after 10 years and present it in terms of a lesson learned. Methods and Materials A working group (WG), led by a qualified clinical risk engineer, which included radiation oncologists, physicists, a rad...
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#2Giulia MarvasoH-Index: 13
Last. Piet OstH-Index: 41
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Abstract Background and purpose Between 30% and 47% of patients treated with definitive radiotherapy (RT) for prostate cancer are at risk of intraprostatic recurrence during follow-up. Re-irradiation with stereotactic body RT (SBRT) is emerging as a feasible and safe therapeutic option. However, no consensus or guidelines exist on this topic. The purpose of this ESTRO ACROP project is to investigate expert opinion on salvage SBRT for intraprostatic relapse after RT. Materials and Methods A 40-it...
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#1Pierina NavarriaH-Index: 25
#2Federico PessinaH-Index: 17
Last. Marta Scorsetti (Humanitas University)H-Index: 44
view all 15 authors...
Abstract Background The standard of care for elderly, newly-diagnosed glioblastoma patients consists, if feasible, of surgical resection followed by a short course of radiation therapy (RT) with concomitant and adjuvant temozolomide chemotherapy (TMZCHT). To date, the literature lacks of consistence in the definition of elderly, if older than 65 years, or 70 years. Aim of this study was to explore whether differences exist between these two cohorts, comparing outcomes using a propensity score ma...
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#1Andrea Costantino (Humanitas University)H-Index: 6
#2Giuseppe Mercante (Humanitas University)H-Index: 18
Last. Armando De Virgilio (Humanitas University)H-Index: 25
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PURPOSE To define the accuracy of fine-needle aspiration cytology (FNAC) in diagnosing persistent or recurrent neck metastases in previously irradiated patients. METHODS The study was performed according to the PRISMA-DTA guidelines. RESULTS A total of 382 FNACs were used for calculation of diagnostic accuracy parameters. The overall pooled sensitivity and specificity in detecting malignant nodes were 69.1% (95% CI: 56.3%-80.7%; I2 = 79.5%) and 84.2% (95% CI: 71.8%-93.5%; I2 = 87.0%), respective...
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#1Mauro LoiH-Index: 13
#2Tiziana ComitoH-Index: 20
Last. Marta Scorsetti (Humanitas University)H-Index: 44
view all 12 authors...
Stereotactic Body Radiotherapy (SBRT) emerged as a valuable option in early to advanced-stage Hepatocellular Carcinoma (HCC) as defined by Barcelona Clinic Liver Cancer (BCLC) system. The aim of our study is to evaluate SBRT in HCC patients and to identify predictors of outcome and toxicity. A retrospective review of HCC patients treated at our Institution between November 2011 and December 2018 was carried out. SBRT was delivered in 3-10 fractions to a median Biologically Effective Dose (BED10)...
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#1Giulia Marvaso (IEO: European Institute of Oncology)H-Index: 13
#2Luca NicosiaH-Index: 10
Last. Stefano Arcangeli (University of Milan)H-Index: 24
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Radiotherapy (RT) is rarely used in the palliative management of muscle-invasive bladder cancer (MIBC). This survey aims to explore current care patterns within the Italian Radiation Oncologist community on this topic. In 2020, the uro-oncological study group of the Italian Association of Radiotherapy and Clinical Oncology (AIRO) conducted a survey evaluating the RT role in advanced MIBC. An electronic questionnaire was administered online to the society members asking for: general consideration...
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#1Ciro Franzese (Humanitas University)H-Index: 19
#2Antonella FogliataH-Index: 55
Last. Marta Scorsetti (Humanitas University)H-Index: 44
view all 10 authors...
Background: The purpose of the study was to evaluate the toxicity and outcome of nasopharyngeal carcinoma patients treated using 3-dimensional conformal radiotherapy (3DCRT) or volumetric modulated arc therapy (VMAT) technique. Material and methods: 68 patients treated between 2006 and 2018 were retrospectively analysed. Since 2009 patients received 3DCRT with 50/70 Gy to the elective/boost volumes in 35 fractions; from then, VMAT with simultaneous integrated boost (SIB) with 54.45/69.96 Gy in 3...
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