James B. Wetmore
Hennepin County Medical Center
Internal medicineUrologyEndocrinologyRenal functionCardiologyRetrospective cohort studyIntensive care medicineHazard ratioHemodialysisKidney diseaseSecondary hyperparathyroidismDiseaseDialysisParathyroid hormonePopulationEnd stage renal diseaseProportional hazards modelNephrologyMedicineGastroenterology
Publications 142
#1James B. WetmoreH-Index: 24
#2Kirsten L. Johansen (HCMC: Hennepin County Medical Center)H-Index: 74
Last. Eric D. WeinhandlH-Index: 26
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Background: The COVID-19 pandemic caused major disruptions to care for patients with advanced CKD. Methods: We investigated the incidence of documented ESKD, ESKD treatment modalities, changes in eGFR at dialysis initiation, and use of incident central venous catheters (CVCs) by epidemiologic week during the first half of 2020 compared to 2017-2019 historical trends, using Centers for Medicare & Medicaid Services data. We used Poisson and logistic regression for analyses of incidence and binary ...
#1Michael E. Ernst (UI: University of Iowa)H-Index: 33
#2Michelle A. Fravel (UI: University of Iowa)H-Index: 5
Last. Karen L. Margolis (HealthPartners)H-Index: 90
view all 12 authors...
Background null Whether long-term blood pressure variability (BPV) predicts kidney function decline in generally healthy older adults is unknown. We investigated this association in ASPirin in Reducing Events in the Elderly (ASPREE) trial participants. null Methods null Between 2010-2014, Australian and US individuals aged ≥70 years ( ≥65 if US minority) were recruited and followed with annual study visits for a median of 4.7 years. Time-to-event analyses and linear mixed effects models were use...
#1Jiannong LiuH-Index: 35
#2Haifeng GuoH-Index: 26
Last. Paul J. Dluzniewski (Amgen)H-Index: 9
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Purpose null Secondary hyperparathyroidism (SHPT) is common among dialysis patients, and calcimimetics are a mainstay of treatment. This study assessed whether cinacalcet use is associated with gastrointestinal bleeding in a large hemodialysis cohort. null Methods null A linked database of clinical records and medical claims for patients receiving hemodialysis in a large dialysis organization, 2007-2010, was used. A nested case-control study was performed among patients aged ≥ 18 years who had r...
#1Eric D. Weinhandl (UMN: University of Minnesota)H-Index: 26
#2David T. GilbertsonH-Index: 57
Last. Kirsten L. JohansenH-Index: 74
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#1James B. Wetmore (UMN: University of Minnesota)H-Index: 24
#2Heng YanH-Index: 5
Last. Charles A. Herzog (UMN: University of Minnesota)H-Index: 76
view all 5 authors...
INTRODUCTION While severe hyperkalemia is commonly encountered, its manifestation in hospitalized patients and related outcomes are unclear. We aimed to examine development of hyperkalemia in hospitalized patients and associated outcomes. METHODS Data from a county hospital electronic health record were used to assess all inpatient admissions, 2012-2016, for non-dialysis-dependent patients with ≥1 K value for development of hyperkalemia. Unadjusted odds ratios (ORs) were calculated for associati...
#1JoAnn M. Sperl-Hillen (HealthPartners)H-Index: 24
#2A. Lauren Crain (HealthPartners)H-Index: 27
Last. Patrick J. O'Connor (HealthPartners)H-Index: 70
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Abstract null null Background null We describe a clinic-randomized trial to improve chronic kidney disease (CKD) care through a CKD-clinical decision support (CKD-CDS) intervention in primary care clinics and the challenges we encountered due to COVID-19 care disruption. null null null Methods/design null Primary care clinics (N = 32) were randomized to usual care (UC) or to CKD-CDS. Between April 17, 2019 and March 14, 2020, more than 7000 patients had accrued for analysis by meeting study-elig...
#1David T. GilbertsonH-Index: 57
#2Heng YanH-Index: 5
Last. Suying LiH-Index: 42
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Background: In dialysis patients with anemia, avoiding red blood cell transfusions is preferable. We sought to develop and validate a novel transfusion prediction risk score for patients receiving maintenance hemodialysis. Methods: This retrospective cohort study used United States Renal Data System data to create a model development cohort (point prevalent hemodialysis patients on November 1, 2012) and a validation cohort (point prevalent hemodialysis patients on August 1, 2013). We characteriz...
BACKGROUND Reports from around the world have indicated a fatality rate of patients with coronavirus disease 2019 (COVID-19) in the range of 20%-30% among patients with ESKD. Population-level effects of COVID-19 on patients with ESKD in the United States are uncertain. METHODS We identified patients with ESKD from Centers for Medicare and Medicaid Services data during epidemiologic weeks 3-27 of 2017-2020 and corresponding weeks of 2017-2019, stratifying them by kidney replacement therapy. Outco...
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