Jie Yan
Central South University
GeneAnalytical chemistryDetection limitInternal medicineDownregulation and upregulationGenomeMolecular biologyTransfer RNARetrospective cohort studyNeuroscienceHeavy strandChemistryGenetic markerChinaPhylogenetic treeImmunologyMitochondrial DNAPropidium iodideNanoclustersDiseaseNeurotoxicityMeth-MethamphetaminePopulationChromatographyIncidence (epidemiology)NecrosisGeneticsMedicineBiologyMechanism (biology)FluorescenceNecroptosisPharmacology
29Publications
11H-index
319Citations
Publications 30
Newest
#1Lvshuang Liao (Hunan Institute of Science and Technology)H-Index: 10
#2Shuang Lu (CSU: Central South University)H-Index: 4
Last. Jie Yan (XMU: Xinjiang Medical University)H-Index: 11
view all 11 authors...
Methamphetamine (METH) is one of the most widely abused synthetic drugs in the world. The users generally present hyperthermia (HT) and psychiatric symptoms. However, the mechanisms involved in METH/HT-induced neurotoxicity remain elusive. Here, we investigated the role of heat shock protein 90 alpha (HSP90α) in METH/HT (39.5°C)-induced necroptosis in rat striatal neurons and an in vivo rat model. METH treatment increased core body temperature and up-regulated LDH activity and the molecular expr...
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#1Shuang Lu (CSU: Central South University)H-Index: 4
#2Yan-Di Yang (CSU: Central South University)H-Index: 1
Last. Jie Yan (CSU: Central South University)H-Index: 11
view all 6 authors...
Source
#1He Yan (CSU: Central South University)H-Index: 1
#2Shanshan Lu (CSU: Central South University)H-Index: 3
Last. Jie Yan (CSU: Central South University)H-Index: 11
view all 8 authors...
BACKGROUND: Multiorgan injury has been implicated in patients with coronavirus disease 2019 (COVID-19). We aim to assess the impact of organ injury (OI) on prognosis according to the number of affected organs at admission. METHODS: This is a retrospective cohort study of patients with confirmed COVID-19 in Wuhan Third Hospital & Tongren Hospital of Wuhan University from February 17 to March 22, 2020. We classified the patients according to the presence and number of damaged organs (heart, liver,...
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#1Weitao Yan (CSU: Central South University)H-Index: 4
#2Zhen Wang (Jiangnan University)H-Index: 1
Last. Jie Yan (CSU: Central South University)H-Index: 11
view all 10 authors...
: Fish bile has long been considered to have therapeutic benefits in folk medicine in some Asian countries. However, poisoning incidents and even death sporadically occurred when people consumed fish bile. Herein, we summarize the main characteristics of fish bile poisoning in China including clinical symptoms, treatment strategies, and factors being associated with death and affecting prognosis, hoping to provide a reference for the diagnosis and treatment of fish bile poisoning, as well as for...
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#1Li-Min Guo (CSU: Central South University)H-Index: 6
#2Zhen Wang (CSU: Central South University)H-Index: 6
Last. Kun Xiong (CSU: Central South University)H-Index: 20
view all 11 authors...
Methamphetamine is one of the most prevalent drugs abused in the world. Methamphetamine abusers usually present with hyperpyrexia (39°C), hallucination and other psychiatric symptoms. However, the detailed mechanism underlying its neurotoxic action remains elusive. This study investigated the effects of methamphetamine + 39°C on primary cortical neurons from the cortex of embryonic Sprague-Dawley rats. Primary cortex neurons were exposed to 1 mM methamphetamine + 39°C. Propidium iodide staining ...
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#1Shanshan Lu (CSU: Central South University)H-Index: 3
#2Xue Yang (CSU: Central South University)H-Index: 5
Last. Jie Yan (CSU: Central South University)H-Index: 11
view all 9 authors...
: Given the importance of non-coding RNAs in modulating normal brain functions and their implications in the treatment of neurological disorders, non-coding RNA-based diagnostic and therapeutic strategies have shown great clinical potential. Circular RNAs (circRNAs) have emerged as potentially important players in this field. Recent studies have indicated that circRNAs might play vital roles in Alzheimer's disease, Parkinson's disease, ischemic brain injury, and neurotoxicity. However, the mecha...
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#1Xingmei Li (CSU: Central South University)H-Index: 5
#2Leiming Han (CSU: Central South University)H-Index: 2
Last. Jifeng Cai (CSU: Central South University)H-Index: 16
view all 9 authors...
Traumatic brain injury (TBI), known as intracranial injury, has been a serious threat to human health. The nonspecific and variable symptoms of TBI have motivated extensive research on miRNAs that serve as significant biomarkers for the TBI diagnosis. However, the current detection methods of TBI miRNAs are conducted only at the in vitro level and involve complex operation systems. Herein, we proposed a novel fluorescence biosensing strategy for cell imaging and rapid detection of Let-7i (a kind...
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#1Zhen Wang (Jiangnan University)H-Index: 1
#2Li-Min Guo (CSU: Central South University)H-Index: 6
Last. Kun Xiong (CSU: Central South University)H-Index: 20
view all 8 authors...
Abstract This review briefly introduces the mechanism and detection methods of necroptosis in recent years. The most significant points of this review focus on the involvement of necroptotic proteins in disease progression. The following aspects are summarized: 1) RIPs, MLKL, and the upstream and downstream molecules that mediate necroptosis; 2) The development of detection methods for necroptosis; 3) The involvement of related necroptotic proteins in diverse diseases etiology; and 4) The applic...
Source
#1Xue Yang (CSU: Central South University)H-Index: 5
#2Yong Wang (CSU: Central South University)H-Index: 3
Last. Jie Yan (CSU: Central South University)H-Index: 11
view all 11 authors...
Methamphetamine (METH) is a popular new-type psychostimulant drug with complicated neurotoxicity. In spite of mounting evidence on METH-induced damage of neural cell, the accurate mechanism of toxic effect of the drug on central nervous system has not yet been completely deciphered. Besides, effective treatment strategies toward METH neurotoxicity remain scarce and more efficacious drugs are to be developed. In this review, we summarize cellular and molecular bases that might contribute to METH-...
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#1Weicheng Duan (CSU: Central South University)H-Index: 2
#2Lingmei Lan (CSU: Central South University)H-Index: 6
Last. Jifeng Cai (CSU: Central South University)H-Index: 16
view all 7 authors...
Estimation of postmortem interval (PMI) plays a crucial role in forensic study and identification work. Because of the unique anatomy location, vitreous humor is considered to be used for estima- ting PMI, which has aroused interest among scholars, and some researches have been carried out. The detection techniques of vitreous humor are constantly developed and improved which have been gradually applied in forensic science, meanwhile, the study of PMI estimation using vitreous humor is updated r...
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