Gennaro Nappo
Humanitas University
CancerInternal medicineRadiologySurgeryPathologyOncologyPathologicalPancreasPancreaticoduodenectomyPancreatic cancerLymph nodePancreatic fistulaAdenocarcinomaPeriampullary cancerPancreatic ductal adenocarcinomaIn patientPost operativeCancer researchPancreatic juiceGeneral surgeryMedicineCohortGastroenterology
Publications 54
Borderline resectable (BR) pancreatic ductal adenocarcinoma (PDAC) is currently a well-recognized entity, characterized by some specific anatomic, biological and conditional features: It includes patients with a stage of disease intermediate between the resectable and the locally advanced ones. The term BR identifies a tumour with an aggressive biological behaviour, on which a neoadjuvant approach instead of an upfront surgery one should be preferred, in order to obtain a radical resection (R0) ...
#1Gennaro NappoH-Index: 7
#2Domenico Borzomati (Università Campus Bio-Medico)H-Index: 19
Last. Damiano Caputo (Università Campus Bio-Medico)H-Index: 14
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Background There is extreme heterogeneity in the available literature on the determination of R1 resection rate after pancreatoduodenectomy (PD); consequently, its prognostic role is still debated. The aims of this multicenter randomized study were to evaluate the effect of sampling and clearance definition in determining R1 rate after PD for periampullary cancer and to assess the prognostic role of R1 resection. Methods PD specimens were randomized to Leeds Pathology Protocol (LEEPP) (group A) ...
#1Giovanni Capretti (Humanitas University)H-Index: 16
#2Greta DonisiH-Index: 2
Last. Alessandro Zerbi (Humanitas University)H-Index: 57
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PURPOSE Patients with fistula risk score (FRS) ≥7 are at the highest risk of developing clinically relevant post-operative pancreatic fistula (CR-POPF). There is no agreement on the management of this subpopulation. The primary outcome of the study was the definition of the role of intraoperative completion pancreatectomy (ICP) in patients at high risk for CR-POPF, as an alternative to high-risk pancreaticoduodenectomy (PD). METHODS This is an observational study set in a single tertiary referra...
#1Gennaro NappoH-Index: 7
#2Jacopo Galvanin (Humanitas University)H-Index: 2
Last. Alessandro Zerbi (Humanitas University)H-Index: 57
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Abstract Background Ampullary carcinoma (AC) is histologically classified as intestinal (In-AC), pancreaticobiliary (Pb-AC) or mixed-AC. The prognostic role of AC subtypes has been debated and remains unclear. The aims of this study were to evaluate outcomes after pancreatoduodenectomy (PD) for each subtype of AC and to compare these with pancreatic ductal adenocarcinoma [PDAC] and distal cholangiocarcinoma [DCC]. Methods PDs performed for AC between 2010 and 2018 were retrospectively evaluated....
#1Roberta Elisa Rossi (University of Milan)H-Index: 26
#3Anna Caterina Milanetto (UNIPD: University of Padua)H-Index: 9
Last. Sara Massironi (University of Milan)H-Index: 27
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Purpose Pretreatment staging is the milestone for planning either surgical or endoscopic treatment in duodenal neuroendocrine neoplasms (dNENs). Herein, a series of surgically treated dNEN patients was evaluated to assess the concordance between the pre- and postsurgical staging. Methods Retrospective analysis of patients with a histologically confirmed diagnosis of dNENs, who underwent surgical resection observed at eight Italian tertiary referral centers. The presurgical TNM stage, based on th...
#1Gaëtan-Romain Joliat (UNIL: University of Lausanne)H-Index: 12
#2Pierre Allemann (UNIL: University of Lausanne)H-Index: 20
Last. Markus Schäfer (UNIL: University of Lausanne)H-Index: 40
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Abstract Background Resection margin status and lymph node (LN) involvement are known prognostic factors for patients who undergo pancreatoduodenectomy for pancreatic ductal adenocarcinoma (PDAC). This study aimed to compare overall survival (OS) and disease-free survival (DFS) by resection margin status in patients with PDAC and LN involvement. Methods A retrospective international multicentric study was performed including four Western centers. Multivariable Cox analysis was performed to ident...
#1Valeria SmiroldoH-Index: 4
#2Alessandro ZerbiH-Index: 57
Last. Andrea LaniaH-Index: 13
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#2Ismail LabgaaH-Index: 15
Last. Markus SchäferH-Index: 40
view all 14 authors...
#1Gennaro NappoH-Index: 7
#2Niccola Funel (UniPi: University of Pisa)H-Index: 31
Last. Alessandro Zerbi (Humanitas University)H-Index: 57
view all 8 authors...
Serous cysto-adenoma (SCA) is a rare benign neoplasm of the pancreas. SCA can mimic other pancreatic lesions, such as neuroendocrine tumours. 68Gallium-DOTA-peptide Positron Emission Tomography (PET) is able to image in vivo the over-expression of the somatostatin receptors, playing an important role for the identification of neuroendocrine neoplasms. We reported a case of 63-year-old man, with a solid lesion of 7 cm of diameter of the body–tail of the pancreas. Two fine-needle-aspirations (FNA)...
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