Keigo Saeki
Nara Medical University
ExcretionCircadian rhythmInternal medicineEndocrinologyCross-sectional studyDemographyOdds ratioPhysical therapyProspective cohort studyGeriatric Depression ScaleMelatoninActigraphyBody mass indexLight intensityConfidence intervalDiabetes mellitusMedicineCohortGerontologyConfoundingBlood pressure
134Publications
24H-index
1,842Citations
Publications 133
Newest
#1Yoshiyuki Abe (Juntendo University)H-Index: 6
#2Keigo Saeki (Nara Medical University)H-Index: 24
Last. Naoto Tamura (Juntendo University)H-Index: 19
view all 9 authors...
Objectives: Malignant rheumatoid arthritis (MRA) is defined as rheumatoid arthritis (RA) with systemic vasculitis or other severe extra-articular manifestations. Japan has a nationwide database for...
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#1Tadanobu Yoshikawa (Nara Medical University)H-Index: 4
#2Kenji Obayashi (Nara Medical University)H-Index: 19
Last. Nahoko Ogata (Nara Medical University)H-Index: 30
view all 5 authors...
Purpose Asymmetric dimethylarginine (ADMA), a potent endogenous inhibitor of nitric oxide synthase, may be involved in the pathophysiology of glaucoma by dysfunctioning nitric oxide and oxidative stress. The purpose of this study was to determine whether the serum ADMA level is associated with the severity of glaucoma. Methods One hundred twenty-five patients with glaucoma (mean age 69.4 years) were analyzed in this cross-sectional study. The severity of glaucoma was determined by the visual fie...
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#1Kimiko Tomioka (Nara Medical University)H-Index: 27
#2Midori Shima (Nara Medical University)H-Index: 39
Last. Keigo Saeki (Nara Medical University)H-Index: 24
view all 3 authors...
BACKGROUND Higher smoking prevalence in people with serious psychological distress (SPD) is well-recognized. However, gender and age differences in the association between heaviness of cigarette smoking and SPD have not been fully investigated. METHODS We used anonymized data from a nationally representative survey in Japan (33,925 men and 37,257 women). SPD was measured using the Kessler 6-item Psychological Distress Scale and defined as ≥ 13 points. Multiple logistic regression analyses strati...
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#1Yuichi Esaki (Fujita Health University)H-Index: 5
#2Kenji Obayashi (Nara Medical University)H-Index: 19
Last. Tsuyoshi Kitajima (Fujita Health University)H-Index: 34
view all 6 authors...
Objective:Sleep disturbance, a core feature of bipolar disorder, is associated with residual mood symptoms, mood episode recurrence and suicide ideation. We investigated the effect of evening light...
1 CitationsSource
#1Yuichi Esaki (Fujita Health University)H-Index: 5
#2Kenji Obayashi (Nara Medical University)H-Index: 19
Last. Tsuyoshi Kitajima (Fujita Health University)H-Index: 34
view all 6 authors...
Abstract Obesity and overweight are highly prevalent in individuals with bipolar disorder and are associated with a risk of developing not only physical but also mental problems. The current study aimed to determine the association between bedroom light exposure at night and obesity in individuals with bipolar disorder. This cross-sectional study enrolled 200 outpatients with bipolar disorder. The light intensity in the bedroom between bedtime and rising time was measured for seven consecutive n...
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#1Yoshiaki Tai (Nara Medical University)H-Index: 3
#2Kenji Obayashi (Nara Medical University)H-Index: 19
Last. Keigo Saeki (Nara Medical University)H-Index: 24
view all 7 authors...
Study objectives Passive body heating in controlled settings could shorten sleep onset latency (SOL). The hypothesized mechanism is vasodilation-induced heat loss before bedtime. However, this evidence is based on small sample size studies in specific populations. Thus, we analyzed the association of hot water bathing based on before-bedtime timing with SOL and heat loss in a large study population of older adults. Methods We conducted a longitudinal analysis using repeated measurements of hot w...
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#1Yuichi EsakiH-Index: 5
#2Kenji Obayashi (Nara Medical University)H-Index: 19
Last. Tsuyoshi Kitajima (Fujita Health University)H-Index: 34
view all 6 authors...
OBJECTIVE Light therapy has been suggested to have a curative effect on bipolar depression; however, preventive effects of light exposure on depressive episodes remain unclear. This study evaluated whether daytime light exposure in real-life situations was associated with a preventive effect on relapse into depressive episodes in patients with bipolar disorder. METHODS This prospective, naturalistic, observational study was conducted in Japan between August 2017 and June 2020. Outpatients with b...
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#1Kimiko Tomioka (Nara Medical University)H-Index: 27
#2Midori Shima (Nara Medical University)H-Index: 39
Last. Keigo Saeki (Nara Medical University)H-Index: 24
view all 3 authors...
Purpose Previous studies have reported a positive association between poor health-related quality of life (HRQOL) and disability mainly in relation to the physical component of HRQOL. Given the mental component's responsivity to interventions, this study aimed to investigate whether the mental component of HRQOL independently predicted functional disability. Methods We targeted all residents aged ≥ 65 years in one municipality and analyzed 3858 men and 4475 women without disability at baseline (...
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#1Yasuko FuruichiH-Index: 1
#2Takafumi Sakakibara (Nara Medical University)
Last. Midori Shima (Nara Medical University)H-Index: 39
view all 11 authors...
Abstract Background There is a paucity of studies on self-assessed generic health-related quality of life (HRQOL) in children with epilepsy. The purpose of this study was to investigate generic HRQOL and associated factors among Japanese children with epilepsy. Methods In this clinic-based study, 277 children (aged 8–18 years) with epilepsy and 429 children without any chronic illnesses were recruited. HRQOL was evaluated using the Japanese version of the KIDSCREEN-52 self-reported questionnaire...
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#1Kazuki Okumura (Nara Medical University)H-Index: 6
#2Kenji Obayashi (Nara Medical University)H-Index: 19
Last. Keigo Saeki (Nara Medical University)H-Index: 24
view all 8 authors...
Aims To investigate the association between B-type natriuretic peptide (BNP) and nocturia among community-dwelling males and females. Methods A total of 1096 participants (mean age 71.9 ± 7.1 years, 518 [47.2%] males) were included in the study. The number of nocturnal voids was recorded in a self-reported urination diary, and nocturia was defined as two or more voids per night. Daytime serum concentration of the N-terminal fragment of BNP precursor (NT-proBNP) was measured. Multivariable logist...
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