Hye-Young Shin
Catholic University of Korea
AnatomyOphthalmologyOptometryInternal medicineSurgerySingle-nucleotide polymorphismMinor allele frequencyTomographyAlleleMaterials scienceImmunologyVisual fieldLaminaVisual acuityGlaucomaCytokineOptical coherence tomographyOptic discFovea centralisNormal tension glaucomaNerve fiber layerRetinalOptic nerveIntraocular pressureInner plexiform layerGanglionCirrusPopulationOptic diskBlind spotGenetic predispositionMedicine
27Publications
10H-index
525Citations
Publications 25
Newest
#1Hae-Young Lopilly Park (St Mary's Hospital)H-Index: 27
#2Da Young Shin (St Mary's Hospital)H-Index: 3
Last. Na Young Lee (St Mary's Hospital)H-Index: 7
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This study investigated the predicted risk factors for the development of normal-tension glaucoma (NTG) in NTG suspects. A total of 684 eyes of 379 NTG suspects who were followed-up for at least 5 years were included in the study. NTG suspects were those having (1) intraocular pressure within normal range, (2) suspicious optic disc (neuroretinal rim thinning) or enlarged cup-to-disc ratio (≥ 0.6), but without definite localized retinal nerve fiber layer (RNFL) defects on red-free disc/fundus pho...
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#1Seung-Hyun Jung (Catholic University of Korea)H-Index: 20
#2Young Chun Lee (Catholic University of Korea)H-Index: 11
Last. Hye-Young Shin (Catholic University of Korea)H-Index: 10
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Previous studies have reported the association of the S1 RNA binding domain 1 (SRBD1) gene with open-angle glaucoma in various ethnic populations. However, in those studies, the definition of the patients differed, as did the results. Therefore, the relevance of the SRBD1 gene to normal tension glaucoma (NTG) appears uncertain at present. Thus, we investigated the relationship between the SRBD1 gene and NTG in a Korean NTG cohort.In total, 159 unrelated Korean patients with NTG and 103 Korean co...
1 CitationsSource
#1Seung-Hyun Jung (Catholic University of Korea)H-Index: 20
#2Young Chun Lee (Catholic University of Korea)H-Index: 11
Last. Hye-Young Shin (Catholic University of Korea)H-Index: 10
view all 4 authors...
ABSTRACTPurpose: Ankyrin repeats and suppressor of cytokine signaling box-containing protein 10 (ASB10) was identified as a novel gene for glaucoma. Since then, there have been reports on the assoc...
1 CitationsSource
#1Seung-Hyun Jung (Catholic University of Korea)H-Index: 20
#2Young Chun Lee (Catholic University of Korea)H-Index: 11
Last. Hye-Young Shin (Catholic University of Korea)H-Index: 10
view all 4 authors...
Background Previous studies have reported the association of HK2 and NCK2 genes with normal-tension glaucoma (NTG) in Japan, but there has been no follow-up study in other countries, so the relevance of these genes to NTG appears uncertain at present. Thus, we investigated the relationship between the HK2 and NCK2 genes and NTG in a Korean NTG cohort.
1 CitationsSource
#1Hye-Young Shin (Catholic University of Korea)H-Index: 10
#2Hae-Young Lopilly Park (Catholic University of Korea)H-Index: 27
Last. Chan Kee Park (Catholic University of Korea)H-Index: 27
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Abstract Objective To compare the 24-2 and 10-2 visual fields (VFs) and investigate the degree of differences between the 2 tests in glaucomatous eyes with central VF defects. Design Retrospective study. Participants In all, 99 eyes of 99 glaucoma patients who underwent both the 24-2 VF and 10-2 VF tests within 6 months were enrolled. Methods Glaucomatous eyes with damage involving a central VF defect were divided into 3 groups based on the average total deviation (TD) of 12 central points in th...
1 CitationsSource
#1Joo Young Kim (Catholic University of Korea)H-Index: 4
#2Mee Yon LeeH-Index: 7
Last. Hye-Young ShinH-Index: 10
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RATIONALE: We report a rare case of neurofibroma in the form of tarsal conjunctival thickening of the eyelid in patients with neurofibromatosis type 1 (NF1), common ocular complications of which are Lisch nodules, choroidal nodules, and optic nerve glioma. PATIENT CONCERNS: A 46-year-old female patient was diagnosed with neurofibroma after biopsy and removal of 2 lumbar level intradural masses 15 years ago. She was being monitored without recurrence. When the patient visited our hospital, multip...
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#1Jin A ChoiH-Index: 13
#2Hye-Young ShinH-Index: 10
Last. Chan Kee Park (Catholic University of Korea)H-Index: 27
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Background/Aims. To investigate the patterns of retinal ganglion cell damage at different stages of glaucoma, using the circumpapillary retinal nerve fiber layer (RNFL) and macula ganglion cell-inner plexiform layer (GCIPL) thicknesses. Methods. In 296 eyes of 296 glaucoma patients and 55 eyes of 55 healthy controls, the correlations of mean deviation (MD) with the superior and inferior quadrant RNFL/GCIPL thickness (defined as the average of three superior and inferior sectors, resp.) were anal...
9 CitationsSource
#1Hye-Young Shin (Catholic University of Korea)H-Index: 10
#2So Hee KimH-Index: 1
Last. Young Chun LeeH-Index: 11
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RATIONALE: Occlusive cerebrovascular disease is the most common cause of homonymous hemianopia (HH) with macular sparing. PATIENT CONCERNS: A 61-year-old man came to our ophthalmology clinic complaining of right-side hemianopia. Ophthalmic examination, visual field (VF) examination, and brain magnetic resonance imaging (MRI) were performed. DIAGNOSES: He had right HH without macular sparing on the initial VF test. And brain MRI 6 days after the visual symptoms began revealed a left occipital inf...
3 CitationsSource
#1Hye-Young ShinH-Index: 10
#2So Hee KimH-Index: 1
Last. Young Chun LeeH-Index: 11
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RATIONALE: Posterior reversible encephalopathy syndrome (PRES) is a cliniconeuroradiological entity associated with vasogenic edema. Symptoms may include headache, seizures, altered mental status, and visual impairment. Patients with PRES generally present with neurological deficits. PATIENT CONCERNS: Here, we report an unusual case of a 42-year-old man who presented with sudden bilateral vision loss without any other neurologic symptoms. DIAGNOSES: He was diagnosed with PRES secondary to acute ...
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#1Hye-Young ShinH-Index: 10
#2Sung-Won ParkH-Index: 10
Last. Chan Kee ParkH-Index: 27
view all 7 authors...
PURPOSE: A significant association between primary open-angle glaucoma risk and copy-number variation in the galactosylceramidase (GALC) gene was reported recently. This study investigated whether a heterozygous deletion of the GALC gene plays a significant role in normal-tension glaucoma (NTG) in Koreans. METHODS: A 3-primer polymerase chain reaction assay was used to examine the heterozygous deletion of GALC in all Korean NTG cases (n=276) and controls (n=135). RESULTS: We did not identify any...
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