Noel W. Clarke
University of Salford
CancerInternal medicineUrologySurgeryPathologyOncologyRandomized controlled trialChemistryProstateAndrogen deprivation therapyMetastasisDiseaseProstate cancerBladder cancerDocetaxelGynecologyCancer researchRadiation therapyMedicineBiology
Publications 449
#1H. Rush (UCL: University College London)H-Index: 6
#2Laura Murphy (UCL: University College London)H-Index: 2
Last. Ruth E Langley (UCL: University College London)H-Index: 28
view all 37 authors...
PURPOSEDocetaxel and abiraterone acetate plus prednisone or prednisolone (AAP) both improve survival when commenced alongside standard of care (SOC) androgen deprivation therapy in locally advanced...
Background: The relative cardiovascular safety of gonadotropin-releasing hormone (GnRH) antagonists compared with GnRH agonists in men with prostate cancer and known atherosclerotic cardiovascular ...
#1Julie Nossiter (Lond: University of London)H-Index: 8
#2Melanie Morris (Lond: University of London)H-Index: 9
Last. Paul Cathcart (Guy's and St Thomas' NHS Foundation Trust)H-Index: 13
view all 10 authors...
Improvements in short-term outcomes have been reported for hospitals with higher radical prostatectomy (RP) volumes. However, the association with longer-term functional outcomes is unknown. All patients diagnosed with non-metastatic prostate cancer in the English NHS between 2014 and 2016 who underwent RP (N = 10,089) were mailed a survey ≥18 months after diagnosis. Differences in patient-reported urinary continence and sexual function (EPIC-26 on scale from 0 to 100) by hospital volume group (...
#1Matthew G. Parry (Lond: University of London)H-Index: 8
#2Jemma Boyle (Lond: University of London)H-Index: 2
Last. Heather Payne (UCL: University College London)H-Index: 11
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Many factors are implicated in the potential ‘under-treatment’ of prostate cancer but little is known about the between-hospital variation. The National Prostate Cancer Audit (NPCA) database was used to identify high-risk localised or locally advanced prostate cancer patients in England, between January 2014 and December 2017, and the treatments received. Hospital-level variation in radical local treatment was explored visually using funnel plots. The intra-class correlation coefficient (ICC) qu...
#4Laura Murphy (UCL: University College London)H-Index: 2
#2Luca AfferiH-Index: 6
Last. David NicolH-Index: 21
view all 24 authors...
#1Matthew G. ParryH-Index: 8
#2Julie NossiterH-Index: 8
Last. Noel W. ClarkeH-Index: 72
view all 11 authors...
INTRODUCTION AND OBJECTIVE:No direct comparison has been made between England and the US with respect to the diagnosis and treatment of men with prostate cancer over one contemporary time period. W...
#2Allaudin IssaH-Index: 3
Last. Noel W. Clarke (Salford Royal NHS Foundation Trust)H-Index: 72
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BACKGROUND AND PURPOSE Hemiscrotectomy with en bloc orchidectomy represents a radical primary, completion, or salvage option in men with inguinoscrotal cancers. We describe our surgical technique and peri-operative and oncological outcomes. PATIENTS AND METHODS Retrospective cohort study of 16 men treated at a supra-regional referral centre with open radical hemiscrotectomy with or without en bloc orchidectomy between 2010 and 2020. Peri-operative and survival outcomes were analysed. RESULTS Rad...
#1Gerhardt Attard (UCL: University College London)H-Index: 77
#2Louise Brown (UCL: University College London)H-Index: 21
Last. Nicholas D. James (The Royal Marsden NHS Foundation Trust)H-Index: 68
view all 5 authors...
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