Shlomo Melamed
Sheba Medical Center
AnatomyOphthalmologySurgeryEye diseaseOcular hypertensionGlaucoma surgeryScleraTrabeculectomyVisual acuityGlaucomaIntraocular lensOptic nerveGonioscopyIntraocular pressureTrabecular meshworkImplantRetinal ganglionOpen angle glaucomaIn patientAnesthesiaMedicine
95Publications
27H-index
2,140Citations
Publications 97
Newest
Background: The purpose of this prospective study was to evaluate the efficacy and safety of the Ultrasound Cyclo Plasty (UCP) procedure using high-intensity focused ultrasound in surgery-naive open-angle glaucoma patients. Methods: prospective, non-randomized, single-arm, multicenter clinical trial. Sixty-six eyes with primary open-angle glaucoma, intraocular pressure (IOP) ≥21 mmHg and with no history of filtering surgery were enrolled. Patients were treated by UCP with a therapy probe compris...
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#1Ofira ZlotoH-Index: 8
#2Alon SkaatH-Index: 13
Last. Shlomo MelamedH-Index: 27
view all 7 authors...
Purpose: Relaxin is a polypeptide hormone produced by the corpus luteum and the decidua in females and by the prostate in males. It has vasodilatory and antifibrotic effects. In the past, it has been reported that injection of relaxin hormone has caused a reduction in the intraocular pressure although its mechanism has not yet been fully understood and the expression of relaxin receptors has not yet been evident in the human eye. Therefore, the purpose of this current study was to examine the pr...
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#1Ari LeshnoH-Index: 3
#2Yair RubinsteinH-Index: 1
Last. Alon Skaat (Sheba Medical Center)H-Index: 13
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PRECIS: Ultrasound Cyclo Plasty treatment using High-Intensity Focused Ultrasound is an effective and safe therapy to reduce intra ocular pressure in moderate glaucoma patients as was measured during a 2 years follow up period. PURPOSE: To evaluate the long term safety and efficacy of the Ultrasound Cyclo Plasty (UCP) procedure using high intensity focused ultrasound (HIFU) in moderate glaucoma patients. PATIENTS AND METHODS: A prospective interventional non-comparative study. Fifteen patients (...
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#1Shlomo MelamedH-Index: 27
#2Guy J. Ben SimonH-Index: 28
Last. Gabriel SimonH-Index: 3
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#1Alon SkaatH-Index: 13
#2Oded SagivH-Index: 6
Last. Shlomo MelamedH-Index: 27
view all 6 authors...
PURPOSE: To compare long-term outcomes of Ahmed glaucoma valve (AGV), 24 μm Gold Micro-Shunt (GMS), and 48 μm GMS implantation for treatment of refractory glaucoma. PATIENTS AND METHODS: This was a 3-armed randomized interventional prospective clinical trial. Within an institutional setting, 29 adults (29 eyes) with refractory glaucoma [mean baseline intraocular pressure (IOP) ≥ 22 mm Hg on maximal medication, status post at least 1 failed trabeculectomy, defined visual field defect, and without...
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#1Shlomo Melamed (Sheba Medical Center)H-Index: 27
#2Modi Goldenfeld (Sheba Medical Center)H-Index: 2
Last. Iris Moroz (Sheba Medical Center)H-Index: 7
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PurposeTo evaluate the safety and efficacy of the ultrasonic circular cyclo-coagulation procedure using high-intensity focused ultrasound by a miniaturized annular device containing 6 piezoceramic transducers in patients with refractory glaucoma.MethodsThis was a prospective interventional noncomparative study of 20 eyes of 20 patients with refractory glaucoma. All eyes were treated with 6 activated transducers operating at 21 MHz. Ultrasound biomicroscopy and a complete ophthalmic examination w...
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#1Tamara Wygnanski-Jaffe (Sheba Medical Center)H-Index: 13
#2Abraham Spierer (Sheba Medical Center)H-Index: 21
Last. Itay Ben-Zion (Sheba Medical Center)H-Index: 9
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To report the effect of oral propranolol on intraocular pressure (IOP) in infants newly diagnosed with unilateral Sturge-Weber syndrome (SWS) glaucoma receiving no other treatment.This was a prospective, nonrandomized interventional case series. Four infants presenting with unilateral SWS glaucoma with no prior treatment were treated with oral propranolol at a dose of 2 mg/kg and followed thereafter.Propranolol had a temporary IOP-lowering effect in 3 of 4 children after 1 week of treatment. Thi...
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#1Alon Skaat (Sheba Medical Center)H-Index: 13
#2Modi GoldenfeldH-Index: 7
Last. Shlomo MelamedH-Index: 27
view all 4 authors...
Purpose:To evaluate the safety and efficacy of CO2 laser-assisted deep sclerectomy surgery (CLASS) in patients with open angle glaucoma.Design:A prospective single-arm, nonrandomized clinical investigation for the evaluation of technology.Methods:Fifteen eyes of 15 consecutive patients diagnosed wit
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#1Ygal RotenstreichH-Index: 17
#2Alon SkaatH-Index: 13
Last. Michael BelkinH-Index: 71
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Evaluation of visual field (VF) is important for clinical diagnosis and patient monitoring. The current VF methods are subjective and require patient cooperation. Here we developed a novel objective perimetry technique based on the pupil response (PR) to multifocal chromatic stimuli in normal subjects and in patients with glaucoma and retinitis pigmentosa (RP). A computerized infrared video pupillometer was used to record PR to short- and long-wavelength stimuli (peak 485 nm and 620 nm, respecti...
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