Mathias Steinach
Humboldt University of Berlin
ThermoregulationSpaceflightCircadian rhythmSupine positionEndocrinologyAnimal scienceCore (anatomy)CardiologyDeconditioningBed restHeart ratevitamin D deficiencyBody mass indexBioelectrical impedance analysisArcticHeart rate variabilityMedicineBiologyPhysical medicine and rehabilitationEndurance training
31Publications
9H-index
242Citations
Publications 22
Newest
#1Stefan MendtH-Index: 5
#2Katharina BraunsH-Index: 3
Last. Alexander C. Stahn (Humboldt University of Berlin)
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#1Marc Jörres (Humboldt University of Berlin)
#2Hanns-Christian Gunga (Humboldt University of Berlin)H-Index: 20
Last. Mathias Steinach (Humboldt University of Berlin)H-Index: 9
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Background: Long endurance exercises like ultramarathons are known to elicit various metabolic and physiological changes in the human body. However, little is known about very long duration exercise at low intensities regarding healthy human subjects. Aim: The purpose of this study was to evaluate changes in body composition and metabolism in long endurance but low intensity events. Methods: 25 male and 18 female healthy participants (age 34.6 ± 8.8 years; BMI: 22.4 ± 2.0 kg/m²) of the “100 km M...
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#1Björn Balcerek (Humboldt University of Berlin)H-Index: 1
#2Mathias Steinach (Humboldt University of Berlin)H-Index: 9
Last. Michael Fähling (Humboldt University of Berlin)H-Index: 22
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Oxygen affinity to haemoglobin is indicated by the p50 value (pO2 at 50% O2Hb) and critically determines cellular oxygen availability. Although high Hb-O2 affinity can cause tissue hypoxia under conditions of well O2 saturated blood, individual differences in p50 are commonly not considered in clinical routine. Here, we investigated the diversity in Hb-O2 affinity in the context of physiological relevance. Oxyhaemoglobin dissociation curves (ODCs) of 60 volunteers (18-40 years, both sexes, eithe...
3 CitationsSource
#1Martina A. Maggioni (Humboldt University of Berlin)H-Index: 14
#2Lea C. Rundfeldt (Humboldt University of Berlin)H-Index: 2
Last. Mathias Steinach (Humboldt University of Berlin)H-Index: 9
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Cardiac autonomic modulation of heart rate, assessed by heart rate variability (HRV), is commonly used to monitor training status. HRV is usually measured in athletes after awakening in the morning in the supine position. Whether recording during standing reveals additional information compared to supine remains unclear. We aimed to evaluate the association between short-duration HRV, assessed both in the supine and standing position, and a low-intensity long-duration performance (walking ultram...
1 CitationsSource
#1Mathias Steinach (Humboldt University of Berlin)H-Index: 9
#2Julia Lichti (Humboldt University of Berlin)H-Index: 2
Last. Michael Fähling (Humboldt University of Berlin)H-Index: 22
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4 CitationsSource
#1Camilla Kienast (Humboldt University of Berlin)
#2Hanns-Christian Gunga (Humboldt University of Berlin)H-Index: 20
Last. Mathias Steinach (Humboldt University of Berlin)H-Index: 9
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Abstract Neuropeptide tyrosine (neuropeptide Y or NPY) is one of the most abundant neuropeptides in the mammalian central nervous system and also widely distributed in the peripheral nervous system. Among the many mediators involved in important physiological and psychological systems, NPY in particular appears to be a multisignaling key peptide. The biological actions of NPY are vast and mediated via the Y1, Y2, Y4, and Y5 receptors, which are involved in both essential physiological and pathop...
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Last. Mathias SteinachH-Index: 9
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Abstract Purpose Muscle mass, sustained through buildup exceeding constant parallel breakdown, is mainly regulated through amino acid availability and mechanic stimulation and conveyed through the key mediator mTORC1. Sarcopenia, as age- and immobilization related loss of muscle mass, strength and function, may serve as an analog to muscle deconditioning in space travel. Optimal countermeasures to muscle deconditioning syndromes may be impacted by impaired anabolic response. This review assesses...
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#1Adriane Schalt (UAF: University of Alaska Fairbanks)H-Index: 2
#2Michelle Johannsen (UAF: University of Alaska Fairbanks)H-Index: 4
Last. Mathias Steinach (Charité)H-Index: 9
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Purpose: The objective of this study was to determine alterations in caloric balance, body composition, metabolites, and cytokines in athletes participating in the Yukon Arctic Ultra. Methods: Ten participants traveling on foot in the 2017 692-km event were recruited for the study. Measurements and samples were obtained at pre-event, 278-km (C1), 384-km (C2), and post-event. Body composition measurements were obtained using bioelectrical impedance analysis. Accelerometer devices were utilized to...
4 CitationsSource
#1Martina A. Maggioni (Charité)H-Index: 14
#2Paolo CastiglioniH-Index: 41
Last. Alexander Stahn (Charité)H-Index: 12
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Head-down-tilt bed rest (HDT) mimics the changes in hemodynamics and autonomic cardiovascular control induced by weightlessness. However, the time course and reciprocal interplay of these adaptations, and the effective exercise protocol as a countermeasure need further clarification. The overarching aim of this work (as part of a European Space Agency sponsored long-term bed rest study) was therefore to evaluate the time course of cardiovascular hemodynamics and autonomic control during prolonge...
13 CitationsSource
#1Oliver Opatz (Charité)H-Index: 6
#2Michael Nordine (Charité)H-Index: 2
Last. Martina A. Maggioni (Charité)H-Index: 14
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Orthostatic instability is one of the main consequences of weightlessness or gravity challenge and plays as well a crucial role in public health, being one of the most frequent disease of aging. Therefore, the assessment of effective countermeasures, or even the possibility to predict, and thus prevent orthostatic instability is of great importance. Heat stress affects orthostatic stability and may lead to impaired consciousness and decrease in cerebral perfusion, specifically during the exposur...
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