Massimo Falconi
Vita-Salute San Raffaele University
CancerInternal medicineRadiologySurgeryPathologyOncologyPancreatitisPancreatic diseasePancreatectomyPancreasPancreaticoduodenectomyNeuroendocrine tumorsDiseasePancreatic cancerPancreatic fistulaAdenocarcinomaIn patientGeneral surgeryMedicineGastroenterology
Publications 909
#1Fabio GiannoneH-Index: 2
#2Giovanni CaprettiH-Index: 16
Last. Gabriele GiannottiH-Index: 1
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#1Francesca Aleotti (UniSR: Vita-Salute San Raffaele University)H-Index: 8
#2Rita Nano (UniSR: Vita-Salute San Raffaele University)H-Index: 30
Last. Gianpaolo Balzano (UniSR: Vita-Salute San Raffaele University)H-Index: 44
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#1Irvin M. Modlin (Yale University)H-Index: 81
Last. Lisa Bodei (MSK: Memorial Sloan Kettering Cancer Center)H-Index: 25
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ABSTRACT: null null Background null Biomarkers are key tools in cancer management. In neuroendocrine tumors (NETs), Chromogranin A (CgA) was considered acceptable as a biomarker. We assessed the clinical efficacy of a multigenomic blood biomarker (NETest) to CgA over a 5-year period. null null null Methods null An observational, prospective, cross-sectional, multicenter, multinational, comparative cohort assessment. Cohort #1: NETest evaluation in NETs (1,684) and cancers, benign diseases, contr...
#1Nikolaos MachairasH-Index: 2
#2Dimitri A. RaptisH-Index: 32
Last. Charles J. YeoH-Index: 155
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OBJECTIVE The aim of this study was to evaluate whether neoadjuvant therapy (NAT) critically influenced microscopically complete resection (R0) rates and long-term outcomes for patients with pancreatic ductal adenocarcinoma who underwent pancreatoduodenectomy (PD) with portomesenteric vein resection (PVR) from a diverse, world-wide group of high-volume centers. SUMMARY BACKGROUND DATA Limited size studies suggest that NAT improves R0 rates and overall survival compared to upfront surgery in rese...
#1Stefano Crippa (UniSR: Vita-Salute San Raffaele University)H-Index: 60
#2G. Belfiori (UniSR: Vita-Salute San Raffaele University)H-Index: 6
Last. Massimo Falconi (UniSR: Vita-Salute San Raffaele University)H-Index: 105
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The extension of a partial pancreatectomy up to total pancreatectomy because of positive neck margin examined at intraoperative frozen section (IFS) analysis is an accepted procedure in modern pancreatic surgery with good accuracy. The goal of this practice is to improve the rate of radical (R0) resection in malignant tumors, mainly pancreatic ductal adenocarcinoma (PDAC), and to completely resect pre-invasive neoplasms such as intraductal papillary mucinous neoplasms (IPMNs). In the setting of ...
1 CitationsSource
#1Francesca Aleotti (UniSR: Vita-Salute San Raffaele University)H-Index: 8
#1Aleotti Francesca (UniSR: Vita-Salute San Raffaele University)
Last. Balzano Gianpaolo (UniSR: Vita-Salute San Raffaele University)
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Total pancreatectomy (TP) is a procedure weighed down not only by postoperative morbidity and mortality but also by long-term effects as a consequence of endocrine and exocrine pancreatic insufficiency. While the latter is now managed quite effectively with pancreatic enzyme replacement therapy, the former remains a challenge. The diabetes resulting after TP, with the complete loss of endogenous insulin and contraregulatory hormones, is characterized by important glycemic variations and is, ther...
#1Giampaolo PerriH-Index: 9
Last. Claudio BassiH-Index: 110
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Abstract null null Background null Existing postoperative pancreatic fistula risk scores rely on intraoperative parameters, which limits their value in the preoperative setting. A preoperative predictive model to stratify the risk of developing postoperative pancreatic fistula before pancreatoduodenectomy was built and externally validated. null null null Methods null A regression risk-tree model for preoperative postoperative pancreatic fistula risk stratification was developed in the Verona Un...
1 CitationsSource
#1Claudio Ricci (UNIBO: University of Bologna)H-Index: 28
#2Stefano Partelli (UniSR: Vita-Salute San Raffaele University)H-Index: 43
Last. Riccardo Casadei (UNIBO: University of Bologna)H-Index: 31
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BACKGROUND Outcomes after surgery for sporadic pancreatic neuroendocrine neoplasms (Pan-NENs) were evaluated. METHODS This multicentre study included patients who underwent radical pancreatic resection for sporadic non-functioning Pan-NENs. In survival analysis, the risk of mortality in this cohort was analysed in relation to that of the matched healthy Italian population. Relative survival (RS) was calculated as the rate between observed and expected survival. Factors related to RS were investi...
1 CitationsSource
#1Massimo Falconi (UniSR: Vita-Salute San Raffaele University)H-Index: 105
#1Lianne ScholtenH-Index: 8
#2Sjors KlompmakerH-Index: 13
Last. Mustafa KeremH-Index: 16
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Objective null To assess postoperative 90-day outcomes after minimally invasive (laparoscopic/robot-assisted) total pancreatectomy (MITP) in selected patients versus open total pancreatectomy (OTP) among European centers. null Background null Minimally invasive pancreatic surgery is becoming increasingly popular but data on MITP are scarce and multicenter studies comparing outcomes versus OTP are lacking. It therefore remains unclear if MITP is a valid alternative. null Methods null Multicenter ...