Chunjie Zhao
Shenyang Pharmaceutical University
Pesticide residueHuman decontaminationAnalytical chemistryBiological activityGas chromatographyElectron capture detectorSulfationPesticideMass spectrometryFourier transform ion cyclotron resonanceOrganic chemistryHigh-performance liquid chromatographyChemistryIndole testGlycosideSupercritical fluid extractionGas chromatography–mass spectrometryMetabolomicsCatalpolVanillic acidRehmanniaIndole alkaloidHeptachlorFormic acidAcridoneAtorvastatinAlkaloidPhenolsCaffeic acidGallic acidGynostemma pentaphyllumAbutilonAjmalicineAjmalineGlucuronidationApocynaceaeRehmannia glutinosaFerulic acidRauvolfia verticillataPhenylethanoidHydroxylationProtocatechuic acidRauvolfiaCoumarinBiotransformationIridoid GlycosidesLiver tissueChromatographic separationIntragastric administrationAtomic absorption spectroscopyChromatographyExtraction (chemistry)Amino acidTraditional medicineMedicineQuantitative analysis (chemistry)
8Publications
5H-index
56Citations
Publications 8
Newest
#1Yinan Wang (SPU: Shenyang Pharmaceutical University)H-Index: 7
#2Fei Han (SPU: Shenyang Pharmaceutical University)H-Index: 17
Last. Chunjie Zhao (SPU: Shenyang Pharmaceutical University)H-Index: 5
view all 6 authors...
Cortex Fraxini is an important traditional Chinese medicine. In this work, a rapid and reliable homogenate extraction method was applied for the fast extraction for Cortex Fraxini, and the method was optimized by response surface methodology. Ultra high performance liquid chromatography combined with Fourier transform ion cyclotron resonance mass spectrometry and gas chromatography with mass spectrometry were established for the separation and characterization of the constituents of Cortex Fraxi...
6 CitationsSource
#1Yinan Wang (SPU: Shenyang Pharmaceutical University)H-Index: 7
#2Min Zhao (SPU: Shenyang Pharmaceutical University)H-Index: 8
Last. Chunjie Zhao (SPU: Shenyang Pharmaceutical University)H-Index: 5
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Abstract Esculin, a coumarin derivative found in Fraxinus rhynchophylla , has been reported to possess multiple biological activities. This present study is designed to investigate the metabolic profile of esculin in vivo based on ultra high performance liquid chromatography coupled to Fourier transform ion cyclotron resonance mass spectrometry (UHPLC-FT-ICR-MS) for the first time. After oral administration of esculin (100 mg/kg) for rats, plasma, urine, feces and bile samples were collected to ...
19 CitationsSource
#1Yinan Wang (SPU: Shenyang Pharmaceutical University)H-Index: 7
#2Min Zhao (SPU: Shenyang Pharmaceutical University)H-Index: 8
Last. Chunjie Zhao (SPU: Shenyang Pharmaceutical University)H-Index: 5
view all 4 authors...
AbstractContext Gynostemma pentaphyllum (Thunb.) Makino has been used in traditional medicine for the treatment of hyperlipidaemic with a long history.Objective: The objective of this study was to evaluate the influence of Gynostemma pentaphyllum (GP) and atorvastatin on amino acids from the plasma and liver tissue of hyperlipidaemic rats.Materials and methods The rats were fed a high-fat diet continuously for 11 weeks for the construction of hyperlipidaemic model. The hyperlipidaemic rats were ...
6 CitationsSource
#1Chunlian Tian (SPU: Shenyang Pharmaceutical University)H-Index: 2
#2Miao Wang (SPU: Shenyang Pharmaceutical University)H-Index: 2
Last. Chunjie Zhao (SPU: Shenyang Pharmaceutical University)H-Index: 5
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A method of reversed-phase high-performance liquid chromatography (RP-HPLC) was established for the simultaneous determination of gallic acid, protocatechuic acid, catechin, vanillic acid, caffeic acid, ferulic acid, rutin, quercetin and syriacusin A in the ethanolic extracts from the five parts (roots, stems, leaves, seeds and exocarps) of Abutilon theophrasti Medic. The nine components in the sample were extracted with 70% ethanol solution in an ultrasonic bath for 25 min and chromatographical...
6 CitationsSource
#1Bo Hong (Qiqihar Medical University)H-Index: 1
#2Wen-Jing Li (Qiqihar Medical University)H-Index: 1
Last. Chunjie Zhao (SPU: Shenyang Pharmaceutical University)H-Index: 5
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Rauvolfia verticillata (Lour.) Baill. (also called Luofumu in Chinese) is commonly used in traditional Chinese medicine for lowering blood pressure. In this study, a high-performance liquid chromatography assay using ultraviolet detection is described for the simultaneous measurement of the five bioactive indole alkaloids (sarpagine, yohimbine, ajmaline, ajmalicine and reserpine) in Rauvolfia. The detection of all five compounds was conducted at 280 nm. In quantitative analysis, the five compoun...
13 CitationsSource
#1Bo Hong (Qiqihar Medical University)H-Index: 1
#2Wen-Jing LiH-Index: 1
Last. Chunjie ZhaoH-Index: 5
view all 3 authors...
The study on the Rauvolfia verticillata (Lour.) Baill., which belongs to Apocynaceae, was carried out to look for its chemical constituents and pharmacological activity. The isolation and purification were performed by chromatography on silica gel, Sephadex LH-20 and ODS (octadecyl silane) open column. The structures of obtained compounds were elucidated on the basis of physicochemical properties and spectral analysis. Three indole alkaloids and one acridone alkaloid were isolated from chlorofor...
#1Chunjie Zhao (SPU: Shenyang Pharmaceutical University)H-Index: 5
#2Lu Bai (SPU: Shenyang Pharmaceutical University)H-Index: 1
Last. Chunhong Xin (SPU: Shenyang Pharmaceutical University)H-Index: 1
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A method involving the simultaneous extraction and decontamination of 12 organochlorine pesticides (OCPs) and seven heavy metals (HM) from Rehmannia glutinosa Libosch was established using supercritical fluid extraction (SFE). A gas chromatography (GC) method with electron capture detection was employed for the determination of the OCPs. The quantitative determination of active constituents (iridoid glycoside and catalpol) in Rehmannia glutinosa Libosch was detected by high-performance liquid ch...
1 CitationsSource
#1Chunjie Zhao (SPU: Shenyang Pharmaceutical University)H-Index: 5
#2Lu Bai (SPU: Shenyang Pharmaceutical University)H-Index: 1
Last. Chunhong Xin (SPU: Shenyang Pharmaceutical University)H-Index: 1
view all 5 authors...
A method involving depuration of 12 organochlorine pesticides (OCPs) and 7 heavy metals fromEpimedium brevicornum Maxim was developed using supercritical fluid extraction (SPE). The pesticides in the study consisted of α, β-, γ-, and δ-Benzene hexachloride, Pentachloro-nitrobenzene (PCNB), Pentachloroaniline (PCA), Heptachlor (HEPT), Methyl -pentachlorophe-nyl sulfide (MPCPS), pp’-DDE[1,1-dichloro-2, 2-bis (p-chlorophenyl) ethylene], op’-DDT [1,1,1-trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)...
5 CitationsSource