Takako Saeki
Niigata University
Internal medicinePathologyRenal functionRheumatologyImmunologyMembranous nephropathyRetroperitoneal fibrosisPrednisoloneNephritisRheumatoid arthritisAutoimmune pancreatitisKidney diseaseDiseaseKidneyIgG4-related diseaseFibrosisRenal biopsyNephrologyMedicineGastroenterology
100Publications
29H-index
6,578Citations
Publications 100
Newest
#1Takako SaekiH-Index: 29
#2Mitsuhiro Kawano (Kanazawa University)H-Index: 20
Last. Hitoshi Nakashima (Fukuoka University)H-Index: 41
view all 13 authors...
Source
#1Takako SaekiH-Index: 29
#2Tasuku Nagasawa (Tohoku University)H-Index: 8
Last. Mitsuhiro Kawano (Kanazawa University)H-Index: 20
view all 11 authors...
IgG4-related disease (IgG4-RD) is a fibroinflammatory condition that can affect various organs. The kidney is one of the organs most frequently affected and IgG4-related tubulointerstitial nephritis (TIN) is the most dominant feature.1 However, several radiologically characteristic lesions within the kidney have also been shown to be diagnostic for IgG4-RD affecting the kidney, in the setting of definitively diagnosed IgG4-related lesions in extrarenal organs.2 Therefore the term ‘IgG4-related k...
Source
#1Takako SaekiH-Index: 29
#2Mitsuhiro Kawano (Kanazawa University)H-Index: 20
Last. Hitoshi Nakashima (Fukuoka University)H-Index: 41
view all 13 authors...
Background In 2011, the IgG4-related kidney disease (IgG4-RKD) working group of the Japanese Society of Nephrology proposed diagnostic criteria for IgG4-RKD. The aim of the present study was to validate those criteria and develop a revised version. Methods Between April 2012 and May 2019, we retrospectively collected Japanese patients with kidney disease, for whom data on serum IgG4 values and/or immunohistological staining for IgG4 in renal biopsy samples were available. These patients were cla...
1 CitationsSource
#1Yuhei Fujisawa (Kanazawa University)H-Index: 2
#2Ichiro Mizushima (Kanazawa University)H-Index: 12
Last. Mitsuhiro Kawano (Kanazawa University)H-Index: 21
view all 14 authors...
AbstractObjectives: This study investigated the clinical features of IgG4-RKD patients with hypocomplementemia compared with those without it, so as to clarify the factors related to hypocomplement...
1 CitationsSource
#1Takako SaekiH-Index: 29
#2Mitsuhiro Kawano (Kanazawa University)H-Index: 20
Last. Hitoshi Nakashima (Fukuoka University)H-Index: 41
view all 11 authors...
Background: The 2019 ACR/EULAR classification criteria for IgG4-RD have recently been published1). In the criteria, patients with an inclusion criteria score of >20 without exclusion criteria are classified as having IgG4-RD. Objectives: To validate the 2019 ACR/EULAR classification criteria for IgG4-RD in a Japanese kidney disease cohort. Methods: The study involved Japanese patients diagnosed as having kidney disease between April 2012 and May 2019, for whom sufficient clinical information and...
Source
#1Osamu MoritaH-Index: 6
#2Kazuto MiuraH-Index: 1
Last. Naoto Endo (Niigata University)H-Index: 42
view all 13 authors...
AbstractObjectives: To clarify changes in the incidence of cervical lesions in rheumatoid arthritis (RA) patients with advanced treatment and the impact of cervical lesions on the patients’ quality of life (QOL).Methods: Incidence of radiographic cervical lesions in 1333 RA patients in 2015 was compared with that in our 1999 survey. The association between cervical lesions and QOL evaluated using three different patient-based questionnaires was also analyzed.Results: The incidence of atlantoaxia...
2 CitationsSource
#1Takuji Nakamura (Kanazawa Medical University)H-Index: 9
#2Tomomi Satoh-Nakamura (Kanazawa Medical University)H-Index: 2
Last. Hisanori Umehara (Kanazawa Medical University)H-Index: 43
view all 28 authors...
AbstractBackground: IgG4-related disease (IgG4-RD) is characterized by elevated serum IgG4 and tissue infiltration by IgG4-positive plasma cells. The pathogenesis of this disease is not clear. Tran...
Source
#1Akira IguchiH-Index: 6
#2Suguru Yamamoto (Niigata University)H-Index: 19
Last. Ichiei Narita (Niigata University)H-Index: 39
view all 10 authors...
BACKGROUND: In patients with chronic kidney disease (CKD), dysbiosis in the gastrointestinal microbiome is thought to be associated with increased production of uremic toxins, such as indoxyl sulfate (IS) and p-cresyl sulfate (PCS). Sucroferric oxyhydroxide (SFO), an iron-based phosphate binder, may affect the gastrointestinal microbiome and the production of uremic toxins. We aimed to examine whether SFO administration affected distribution of gastrointestinal microbiome and serum uremic toxin ...
3 CitationsSource
#1Zachary S. Wallace (Harvard University)H-Index: 25
#2Ray NadenH-Index: 6
Last. John H. Stone (Harvard University)H-Index: 76
view all 24 authors...
OBJECTIVE: IgG4-related disease (IgG4-RD) can cause fibroinflammatory lesions in nearly any organ. Correlation among clinical, serologic, radiologic, and pathologic data is required for diagnosis. This work was undertaken to develop and validate an international set of classification criteria for IgG4-RD. METHODS: An international multispecialty group of 86 physicians was assembled by the American College of Rheumatology (ACR) and the European League Against Rheumatism (EULAR). Investigators use...
54 CitationsSource
#1Zachary S. Wallace (Harvard University)H-Index: 25
#2Ray Naden (McMaster University)H-Index: 6
Last. John H. Stone (Harvard University)H-Index: 76
view all 20 authors...
IgG4-related disease (IgG4-RD) can cause fibroinflammatory lesions in nearly any organ. Correlation among clinical, serological, radiological and pathological data is required for diagnosis. This work was undertaken to develop and validate an international set of classification criteria for IgG4-RD. An international multispecialty group of 86 physicians was assembled by the American College of Rheumatology (ACR) and the European League Against Rheumatism (EULAR). Investigators used consensus exe...
109 CitationsSource